5-Chloro-1,6-naphthyridine
Artikel-Nr:
(BOSSBS-13248R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13248R-CY5
Lokale Artikelnummer::
BOSSBS-13248R-CY5
Beschreibung:
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1). Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e., adenylyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, Beta and Gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively (2-5). Most interest in G proteins has been focused on their a subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of G alpha subunits have been identified; these include Gs, Gi, Gq and Ga 12/13 (3,4). The Gi class comprises all the known a subunits that are susceptible to pertussis toxin modifications, including Ga i-1, Ga i-2, Ga i-3, Ga o, Ga t1, Ga t2, Ga z and Ga gust (4). Of these, the three Ga i subtypes function to open atrial potassium channels (6). Ga 16 is a member of the Gq subfamily and is expressed specifically in hematopoietic cells (7).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13248R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13248R-HRP
Lokale Artikelnummer::
BOSSBS-13248R-HRP
Beschreibung:
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1). Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e., adenylyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, Beta and Gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively (2-5). Most interest in G proteins has been focused on their a subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of G alpha subunits have been identified; these include Gs, Gi, Gq and Ga 12/13 (3,4). The Gi class comprises all the known a subunits that are susceptible to pertussis toxin modifications, including Ga i-1, Ga i-2, Ga i-3, Ga o, Ga t1, Ga t2, Ga z and Ga gust (4). Of these, the three Ga i subtypes function to open atrial potassium channels (6). Ga 16 is a member of the Gq subfamily and is expressed specifically in hematopoietic cells (7).
VE:
1 * 100 µl
Artikel-Nr:
(NALG322002-9125)
Lieferant:
Thermo Fisher Scientific
Hersteller-Artikelnummer::
322002-9125
Lokale Artikelnummer::
NALG322002-9125
Beschreibung:
Perform many small-volume applications with Thermo Scientific™ Nalgene™ HDPE diagnostic bottles with closure. These bottles are ideal for use in test kits, sample storage and shipping of small-volume, valuable reagents. They come packed in rigid trays for easy handling.
VE:
1 * 1.328 ST
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Artikel-Nr:
(181-3135)
Lieferant:
KNF
Hersteller-Artikelnummer::
N816.3KT.18
Lokale Artikelnummer::
KNFAN816.3KT.18
Beschreibung:
Ein- oder zweiköpfige trockenlaufende Membranpumpen für vielfältige Anwendungen in Laboratorien. Sie fördern und evakuieren unverfälscht, d.h. die Medien werden nicht verunreinigt. Die Pumpe ist mit einer PTFE-beschichteten Membran mit patentierter Spannungsoptimierung ausgestattet, wodurch die Baugröße der Pumpe verringert und die Lebensdauer der Membran verlängert wird, und ist ideal für aggressive/korrosive Gase und Dämpfe.
VE:
1 * 1 ST
Artikel-Nr:
(APOSOR0875-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR0875-1G
Lokale Artikelnummer::
APOSOR0875-1G
Beschreibung:
Ethyl-4-hydroxy-2-(methylthio)pyrimidine-5-carboxylate
VE:
1 * 1 g
Artikel-Nr:
(APOSOR110045-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR110045-1G
Lokale Artikelnummer::
APOSOR110045-1G
Beschreibung:
Ethyl 2-amino-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate
VE:
1 * 1 g
Lieferant:
Alfa Aesar
Beschreibung:
2-Formylphenylboronsäure ≥97%
Artikel-Nr:
(BOSSBS-2412R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2412R-A750
Lokale Artikelnummer::
BOSSBS-2412R-A750
Beschreibung:
MPG (N-methylpurine DNA glycosylase, or 3-methyladenine (3MeA) DNA glycosylase) repairs the 3MeA lethal lesion blocking DNA replication in Escherichia coli. Analysis of human cDNA libraries found a cDNA that would hybridise to human genomic DNA but not to E. coli or yeast DNA. This MPG gene has been mapped to human chromosome 16 by analysis of a panel of DNAs from mouse/human and hamster/human hybrid cell lines.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2412R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2412R-A488
Lokale Artikelnummer::
BOSSBS-2412R-A488
Beschreibung:
MPG (N-methylpurine DNA glycosylase, or 3-methyladenine (3MeA) DNA glycosylase) repairs the 3MeA lethal lesion blocking DNA replication in Escherichia coli. Analysis of human cDNA libraries found a cDNA that would hybridize to human genomic DNA but not to E. coli or yeast DNA. This MPG gene has been mapped to human chromosome 16 by analysis of a panel of DNAs from mouse/human and hamster/human hybrid cell lines.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2412R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2412R-A555
Lokale Artikelnummer::
BOSSBS-2412R-A555
Beschreibung:
MPG (N-methylpurine DNA glycosylase, or 3-methyladenine (3MeA) DNA glycosylase) repairs the 3MeA lethal lesion blocking DNA replication in Escherichia coli. Analysis of human cDNA libraries found a cDNA that would hybridize to human genomic DNA but not to E. coli or yeast DNA. This MPG gene has been mapped to human chromosome 16 by analysis of a panel of DNAs from mouse/human and hamster/human hybrid cell lines.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1966R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1966R-CY5.5
Lokale Artikelnummer::
BOSSBS-1966R-CY5.5
Beschreibung:
May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-|-Gln-15' and insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1966R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1966R-CY5
Lokale Artikelnummer::
BOSSBS-1966R-CY5
Beschreibung:
May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-|-Gln-15' and insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines.
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
1,6-Diisocyanatohexan, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-8878R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8878R-CY7
Lokale Artikelnummer::
BOSSBS-8878R-CY7
Beschreibung:
Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
VE:
1 * 100 µl
Artikel-Nr:
(SIAL240117-50G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
240117-50G
Lokale Artikelnummer::
SIAL240117-50G
Beschreibung:
1,6-Hexandiol, Sigma-Aldrich®
VE:
1 * 50 g
Lieferant:
Alfa Aesar
Beschreibung:
Bis(triphenylphosphin)nickel(II)chlorid ≥98%
Preis auf Anfrage
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