Sie suchten nach: DISCOVERY+LABWARE

Lieferant: ALLTECH GRACE DISCOVERY SCIENC

Beschreibung: Justierbarer Kolben für 5 g (12 ml Kartusche)

Lieferant: Agilent

Beschreibung: AdvanceBio RP-mAb columns are designed to optimise the performance of intact and reduced mAb analysis when analysing monoclonal antibodies for biopharma discovery, development, and QA/QC applications.

Lieferant: Thermo Fisher Scientific

Beschreibung: Acclaim™ PepMap™ C18 columns are ideal for high-resolution analysis of tryptic, natural, and synthetic peptides. The columns are often applied for LC-MS/MS peptide mapping for protein identification, biomarker discovery, and systems biology. Due to their high loading capacity, the columns are suitable for the analysis of low abundant peptides in complex proteomics samples.

Artikel-Nr: (PRSI92-536)

Lieferant: ProSci Inc.

Hersteller-Artikelnummer:: 92-536

Lokale Artikelnummer:: PRSI92-536

Beschreibung: Pentraxin 2 (PTX2), also known as Serum amyloid P (SAP), is a highly conserved, naturally circulating plasma protein and a soluble pattern recognition receptor of the innate immune system. The unique binding activities indicated that it may play an important role in the removal of damaged tissue. PTX2 belongs to the pentraxin family, is universally present in amyloid deposits. Mouse with targeted deletion of the PTX2 gene shows retarded and reduced induction of experimental reactive systemic (AA type) amyloidosis confirmed that it does indeed contribute to pathogenesis of amyloidosis and is a valid therapeutic target. In recent discovery, PTX2 can be used as a powerful antifibrotic agent to regulate certain monocyte differentiation states.

VE: 1 * 50 µG

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Lieferant: Spectrum Chemical

Beschreibung: Spectrum Chemical bioCERTIFIED™ products are uniquely suited for bioprocessing by biopharmaceutical manufacturers. From drug discovery to pilot and scale-up to production, bioCERTIFIED™ products help simplify and standardize bioprocessing by ensuring consistent raw material quality.

Artikel-Nr: (PRSI47-180)

Lieferant: ProSci Inc.

Hersteller-Artikelnummer:: 47-180

Lokale Artikelnummer:: PRSI47-180

Beschreibung: Epithelium-specific gene regulation plays acritical role during embryogenesis, and the epithelial cell lineage is the first differentiated cell type to appear afterfertilization. Until recently, very few epithelial cell-restricted transcription factors had been described. Members of the ets transcription factor/oncogene family havebeen implicated in human carcinogenesis following the discovery of several distinctchromosomal translocations involving members of the ets family in different types of cancer. ets factors play key roles intranscriptional control of stringently regulated genes, such as genes involved intissue development, differentiation,angiogenesis, cell cycle control and cellproliferation. ESE-1 is the first member of the ets family that was found to be exclusively expressed and inducible inepithelial cells.

VE: 1 * 100 µG

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Artikel-Nr: (PRSI90-527)

Lieferant: ProSci Inc.

Hersteller-Artikelnummer:: 90-527

Lokale Artikelnummer:: PRSI90-527

Beschreibung: IL-24 is a cytokine belonging to the IL-10 family of cytokines that signals through two heterodimeric receptors: IL-20R1/IL-20R2 and IL-22R1/IL-20R2. This interleukin is also known as melanoma differentiation-associated 7 (mda-7) due to its discovery as a tumour suppressing protein. IL-24 appears to control cell survival and proliferation by inducing rapid activation of particular transcription factors called STAT1 and STAT3. It is predominantly released by activated monocytes, macrophages and T helper 2 (Th2) cells and acts on non-haematopoietic tissues such as skin, lung and reproductive tissues. IL-24 performs important roles in wound healing, psoriasis and cancer. IL-24 has antiproliferative properties is inhibiting angiogenesis and may contribute to terminal cell differentiation.

VE: 1 * 25 µG

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Artikel-Nr: (BINH1001298)

Lieferant: Binhold, Paul Lehrmittel

Hersteller-Artikelnummer:: 1001298

Lokale Artikelnummer:: BINH1001298

Beschreibung: The KNM-ER 406, Omo L. 7a-125 skull model is the finest casting produced from scientifically made copies of specimens. This unique KNM-ER 406, Omo L. 7a-125 replica is supplemented by having it displayed on a pedestal that contains a relief map of the geographical area where the skull specimen was found. This KNM-ER 406, Omo L. 7a-125 skull model is a high-quality casting of a reconstruction of the Kalvarium skull (KMN-ER 406) with a partial mandible (Omo L. 7a-125). The Kalvarium skull is approximately 1,7 million years old and was discovered at Lake Rudolph (now called Lake Turkana) in 1970. The partial mandible comes from a different dig but is clearly from the same species. The classification of the species that this skull comes from has not yet been indisputably clarified. Discussions continue as to whether the anatomical features of this skull specimen points to classification as an Australopithecus boisei or a Paranthropus boisei. Example of a pre-human hominid. Discovered at: Lake Turkana, formerly Lake Rudolph Discovery: 1970 Age: about 1,7 million years This KNM-ER 406, Omo L. 7a-125 skull replica is a great tool for teaching and learning the anatomy of early huminid species.

VE: 1 * 1 ST

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 This is a MarketSource item. Additional charges may apply

Artikel-Nr: (PRSI47-131)

Lieferant: ProSci Inc.

Hersteller-Artikelnummer:: 47-131

Lokale Artikelnummer:: PRSI47-131

Beschreibung: Epithelium-specific gene regulation plays acritical role during embryogenesis, and the epithelial cell lineage is the first differentiated cell type to appear after fertilization. Until recently, very few epithelial cell-restricted transcription factors had been described. Members of the ets transcription factor/oncogene family have been implicated in human carcinogenesis following the discovery of several distinctchromosomal translocations involving members of the ets family in different types of cancer. ets factors play key roles intranscriptional control of stringently regulated genes, such as genes involved in tissue development, differentiation,angiogenesis, cell cycle control and cellproliferation. ESE-1 is the first member ofthe ets family that was found to be exclusively expressed and inducible inepithelial cells.

VE: 1 * 100 µG

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Lieferant: ALLTECH GRACE DISCOVERY SCIENC

Beschreibung: Für eine maximale Leistung der heutigen Flash-Instrumente sind die GraceResolv™ Kartuschen mit Davisil® Qualitäts-Kieselsäure gepackt.

Artikel-Nr: (PRSI49-549)

Lieferant: ProSci Inc.

Hersteller-Artikelnummer:: 49-549

Lokale Artikelnummer:: PRSI49-549

Beschreibung: Since their discovery in the early 1990's, the peroxisome proliferator activated receptors (PPARs) have attracted significant attention. This is primarily because PPARs serve as receptors for two very important classes of drugs: the hypolipidemic fibrates and the insulin sensitizing thiazolidinediones. Peroxisome proliferators are non-genotoxic carcinogens that are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family termed PPARs. Nuclear hormone receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate ligand. Upon binding fatty acids or hypolipidemic drugs, PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate the expression of target genes. There are 3 known subtypes of PPARs: PPAR-alpha, PPAR-delta and PPAR-gamma. Mostly target genes are involved in the catabolism of fatty acids. Conversely, PPAR-gamma is activated by peroxisome proliferators such as prostaglandins, leukotrienes and anti-diabetic thiazolidinediones and affects the expression of genes involved in the storage of the fatty acids. PPAR-gamma may also be involved in adipocyte differentiation. It has also been shown that PPARs can induce transcription of acyl coenzyme A oxidase and cytochrome P450 through interaction with specific response elements.

VE: 1 * 50 µG

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Artikel-Nr: (521-4059)

Lieferant: BECKMAN COULTER

Hersteller-Artikelnummer:: 368914

Lokale Artikelnummer:: BECM368914

Beschreibung: LABWARE PKG MIKROPLATTENTRGER KIT 1 * 1 ST

VE: 1 * 1 ST

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Artikel-Nr: (521-4056)

Lieferant: BECKMAN COULTER

Hersteller-Artikelnummer:: 368732

Lokale Artikelnummer:: BECM368732

Beschreibung: LABWARE KIT, JS-5.0 1 * 1 ST

VE: 1 * 1 ST

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Artikel-Nr: (521-4091)

Lieferant: BECKMAN COULTER

Hersteller-Artikelnummer:: 392574

Lokale Artikelnummer:: BECM392574

Beschreibung: LABORGERTESATZ, 8.1/9.1K 1 * 1 ST

VE: 1 * 1 ST

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Artikel-Nr: (65740-U)

Lieferant: Sigma-Aldrich

Hersteller-Artikelnummer:: 65740-U

Lokale Artikelnummer:: SUPL65740-U

Beschreibung: ZR-PS 3UM 5CM X 4.6MM DISCOVERY 1 * 1 Pack.

VE: 1 * 1 Pack.

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Artikel-Nr: (65725-U)

Lieferant: Sigma-Aldrich

Hersteller-Artikelnummer:: 65725-U

Lokale Artikelnummer:: SUPL65725-U

Beschreibung: ZR-CARBON 3UM 5CM X 2.1MM DISCOVERY 1 * 1 Pack.

VE: 1 * 1 Pack.

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