Doxycycline+monohydrate
Lieferant:
Alfa Aesar
Beschreibung:
Acetylene containing reagent with PEG spacer and carboxyl reactivity.
Lieferant:
COMBI-BLOCKS
Beschreibung:
4-Brom-3,5-dimethyl-1-(2-tetrahydropyranyl)-1H-pyrazol
Artikel-Nr:
(ABCRAB106199.0005)
Lieferant:
ABCR
Hersteller-Artikelnummer::
AB106199.0005
Lokale Artikelnummer::
ABCRAB106199.0005
Beschreibung:
Tris(2,2,6,6-tetramethyl-3,5-heptandionato-O,O')europium(III)
VE:
1 * 5 g
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Artikel-Nr:
(BOSSBS-2423R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2423R-A750
Lokale Artikelnummer::
BOSSBS-2423R-A750
Beschreibung:
This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterised by muscle hypertrophy and decreased fat mass.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12259R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12259R-A555
Lokale Artikelnummer::
BOSSBS-12259R-A555
Beschreibung:
Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which are essential interfaces for biological recognition processes. Fucosyltransferases (FucTs) catalyze the covalent association of fucose to different positional linkages on sugar acceptor molecules. The carbohydrate moieties that are generated are covalently attached to cell surfaces and are necessary to ensure a surface contour that satisfies a variety of physiological roles. FucT-XI is a 492 amino acid single-pass type II membrane protein that belongs to the glycosyltransferase 10 family. Localizing to Golgi apparatus, FucT-XI may act as a fucosyltransferase and exists as two alternatively spliced isoforms. The gene encoding FucT-XI maps to mouse chromosome 14 A3.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 36 kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). About 40% of breast carcinomas are positive for Cyclin D1. Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
Artikel-Nr:
(BOSSBS-12259R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12259R-A647
Lokale Artikelnummer::
BOSSBS-12259R-A647
Beschreibung:
Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which are essential interfaces for biological recognition processes. Fucosyltransferases (FucTs) catalyze the covalent association of fucose to different positional linkages on sugar acceptor molecules. The carbohydrate moieties that are generated are covalently attached to cell surfaces and are necessary to ensure a surface contour that satisfies a variety of physiological roles. FucT-XI is a 492 amino acid single-pass type II membrane protein that belongs to the glycosyltransferase 10 family. Localizing to Golgi apparatus, FucT-XI may act as a fucosyltransferase and exists as two alternatively spliced isoforms. The gene encoding FucT-XI maps to mouse chromosome 14 A3.
VE:
1 * 100 µl
Artikel-Nr:
(PIER22331)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
22331
Lokale Artikelnummer::
PIER22331
Beschreibung:
Thermo Scientific Pierce BMB is a mid-length, maleimide crosslinker for covalent, irreversible conjugation between sulfhydryl groups (e.g., protein or peptide cysteines).
VE:
1 * 50 mg
Artikel-Nr:
(BOSSBS-4296R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4296R-CY7
Lokale Artikelnummer::
BOSSBS-4296R-CY7
Beschreibung:
One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction (By similarity). As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4296R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4296R-CY5
Lokale Artikelnummer::
BOSSBS-4296R-CY5
Beschreibung:
One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction (By similarity). As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15165R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15165R-CY3
Lokale Artikelnummer::
BOSSBS-15165R-CY3
Beschreibung:
C3orf14 (chromosome 3 open reading frame 14), also known as HT021, is a 128 amino acid protein that is encoded by a gene mapping to human chromosome 3p14.2. Chromosome 3 is made up of approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13300R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13300R
Lokale Artikelnummer::
BOSSBS-13300R
Beschreibung:
GBE1 is a 702 amino acid protein that is expressed at high levels in muscle and liver and is involved in glycogen biosynthesis. Existing as a monomer, GBE1 catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on a neighboring glycogen chain and, via this catalytic activity, plays an essential role in glycogen accumulation. Defects in the gene encoding GBE1 are the cause of glycogen storage disease type 4 (GSD4) and adult polyglucosan body disease (APBD), the first of which is a metabolic disorder that is associated with the accumulation of polysaccharides and is characterized by liver disease during childhood. Unlike GSD4, APBD is a late-onset disorder that affects the central and peripheral nervous systems and is characterized by cognitive impairment, pyramidal tetraparesis and peripheral neuropathy.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
3,5-Di-tert-butyl-4-hydroxybenzonitril
Artikel-Nr:
(APOSBISN0034-5MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
BISN0034-5MG
Lokale Artikelnummer::
APOSBISN0034-5MG
Beschreibung:
AZD0156 is a potent and selective inhibitors of ATM kinase, with potential chemo-/radio-sensitizing and antineoplastic activities.
VE:
1 * 5 mg
Artikel-Nr:
(FLUO023008-1G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
023008-1G
Lokale Artikelnummer::
FLUO023008-1G
Beschreibung:
Ethyl(3,5-dimethyl-4-methoxybenzoyl)formiat
VE:
1 * 1 g
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Lieferant:
Sigma-Aldrich
Beschreibung:
3,6-Dimethyl-1,4-dioxan-2,5-dion, Sigma-Aldrich®
Preis auf Anfrage
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