Horizontal+Gel+Electrophoresis+Systems
Artikel-Nr:
(BOSSBS-5789R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5789R
Lokale Artikelnummer::
BOSSBS-5789R
Beschreibung:
Zn(2+) acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6092R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6092R
Lokale Artikelnummer::
BOSSBS-6092R
Beschreibung:
RHOBTB1 is a member of the Rho family of the small GTPase superfamily. Is made of a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. Plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6349R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6349R-CY3
Lokale Artikelnummer::
BOSSBS-6349R-CY3
Beschreibung:
May be involved in the regulation of cell-cell interactions or in synatogenesis during the maturation of the nervous system. NERP peptides are involved in the control of body fluid homeostasis by regulating vasopressin release. Antimicrobial peptide VGF[554-577]: Has bactericidal activity against M. luteus, and antifungal activity against P. Pastoris.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6092R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6092R-CY7
Lokale Artikelnummer::
BOSSBS-6092R-CY7
Beschreibung:
RHOBTB1 is a member of the Rho family of the small GTPase superfamily. Is made of a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. Plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system.
VE:
1 * 100 µl
Lieferant:
S.C.A.T.
Beschreibung:
SafetyCaps wurden für die sichere Entnahme von Lösungsmitteln bei der Arbeit mit HPLC/UHPLC-Systemen entwickelt.
Artikel-Nr:
(BOSSBS-9632R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9632R-A555
Lokale Artikelnummer::
BOSSBS-9632R-A555
Beschreibung:
PDZD9 (PDZ domain containing 9) is a 264 amino acid protein that contains one PDZ (DHR) domain and participates in protein binding. Conserved in chimpanzee, dog, cow, mouse and rat, PDZD9 exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 16p12.1. Chromosome 16 encodes over 900 genes, approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. Giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth, and the rare disorder Rubinstein-Taybi syndrome, characterized by mental retardation and predisposition to tumor growth and white blood cell neoplasias, are associated with chromosome 16. Crohn's disease, a gastrointestinal inflammatory condition, and systemic lupus erythematosis are also associated with chromosome 16.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12056R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12056R-A350
Lokale Artikelnummer::
BOSSBS-12056R-A350
Beschreibung:
Serotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it is predominantly expressed in the gut, platelets and central nervous system (CNS). In the CNS, serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors. SR-3 is a ligand-gated ion channel, whereas all other known serotonin receptor subtypes are G protein-coupled receptors. SR-4 mediates widespread effects in central and peripheral nervous systems. SR-7 belongs to the superfamily of G protein-coupled receptors. The gene which encodes SR-7 maps to human chromosome 10q21-q24.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8411R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8411R-HRP
Lokale Artikelnummer::
BOSSBS-8411R-HRP
Beschreibung:
Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins that may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. GAPR-1 (Golgi-associated plant pathogenesis-related protein 1), also known as GLIPR2, is a 154 amino acid lipid anchor protein belonging to the CRISP family. GAPR-1 also shares similarity with the pathogenesis-related protein (PR) superfamily, and may play an important role in the immune system. Existing as a homodimer, GAPR-1 is highly expressed in lung and peripheral leukocytes with minor expression in liver and kidney. Containing a conserved sperm-coating protein (SCP) domain, GAPR-1 binds to negatively charged lipids and may be involved in the differentiation of epithelial cells into mesenchymal cells. Increased expression of GAPR-1 in kidney may contribute to the development of fibrosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8411R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8411R-FITC
Lokale Artikelnummer::
BOSSBS-8411R-FITC
Beschreibung:
Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins that may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. GAPR-1 (Golgi-associated plant pathogenesis-related protein 1), also known as GLIPR2, is a 154 amino acid lipid anchor protein belonging to the CRISP family. GAPR-1 also shares similarity with the pathogenesis-related protein (PR) superfamily, and may play an important role in the immune system. Existing as a homodimer, GAPR-1 is highly expressed in lung and peripheral leukocytes with minor expression in liver and kidney. Containing a conserved sperm-coating protein (SCP) domain, GAPR-1 binds to negatively charged lipids and may be involved in the differentiation of epithelial cells into mesenchymal cells. Increased expression of GAPR-1 in kidney may contribute to the development of fibrosis.
VE:
1 * 100 µl
Lieferant:
ENTEGRIS
Beschreibung:
Available compliant to SEMI Standard F57-0312, the specification for polymer components used in ultrapure water and liquid chemical distribution systems. All wetted parts are molded PFA providing chemical resistance suitable for use in high purity, high corrosive chemical handling applications.
Lieferant:
ENTEGRIS
Beschreibung:
Available compliant to SEMI Standard F57-0312, the specification for polymer components used in ultrapure water and liquid chemical distribution systems. Higher performance with greater back (outlet) pressure capability. All wetted parts are molded PFA providing chemical resistance suitable for use in high purity, high corrosive chemical handling applications.
Artikel-Nr:
(BOSSBS-10332R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10332R-CY7
Lokale Artikelnummer::
BOSSBS-10332R-CY7
Beschreibung:
This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. Nerve growth factor (NGF) is a peptide that plays a key role in the differentiation and survival of neurons in the peripheral nervous system (PNS) and the central nervous system (CNS). VGF is a peptide synthesized and secreted by neurons and is upregulated by NGF in the PC12 cell line. VGF is widely expressed in both the PNS and CNS, but is especially abundant in the adult hypothalamus. VGF plays an essential role in how the brain regulates energy expenditure and body weight. Its expression is rapidly induced by injury, the circadian clock, and neuronal activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12333R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12333R-A750
Lokale Artikelnummer::
BOSSBS-12333R-A750
Beschreibung:
ERMAP is a single-pass type one membrane protein that belongs to the immunoglobulin superfamily. Expressed in cord blood, fetal liver and adult bone marrow, ERMAP is thought to function as a cell adhesion molecule in erythroid cells and is responsible for expression of the Scianna/Radin (Sc/Rd) blood group antigen system. The Sc/Rd system is comprised of seven antigens that are present on the surface of red blood cells and have a variety of functions ranging from protein transport to cell adhesion. These seven blood antigens can differ in their expression within a population and may sometimes differ between mother and child. A fetus expressing different blood antigens than its mother may cause the mother to produce against the fetal blood. This condition is known as hemolytic disease of the newborn (HDN) and is characterised by jaundice, anemia and in some cases, infant death.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5220R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5220R-A750
Lokale Artikelnummer::
BOSSBS-5220R-A750
Beschreibung:
BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants (alpha and beta) produced by alternate splicing, differ in their C-terminal ends. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability. It appears to function in a feedback loop system with caspases. BCL2 inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF1). It can form homodimers, and heterodimers with BAX, BAD, BAK and BclX(L). Heterodimerization with BAX requires intact BH1 and BH2 domains, and is necessary for anti-apoptotic activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2425R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2425R-FITC
Lokale Artikelnummer::
BOSSBS-2425R-FITC
Beschreibung:
Apelin is a neuropeptide expressed in the supraoptic and paraventricular nuclei and is an endogenous ligand for APJ, a G protein-coupled orphan receptor which is an alternative coreceptor with CD4 for HIV-1. Apelin and APJ are ubiquitously expressed in peripheral tissues, with highest levels reported for heart and lungs, as well several regions within the central nervous system. The actions of apelin remain largely unknown: Apelin inhibits HIV-1 entry in cells coexpressing CD4 and APJ; the oral intake of Apelin in colostrum and breast milk could have a role in the modulation of the immune responses in neonates; more recent studies have also indicated a role for Apelin in the central control of body fluid homeostasis, by influencing AVP release and drinking behavior. In the cardiovascular system several actions of Apelin have been described, including endothelium-dependent vasodilatation, vasoconstriction through direct action on smooth muscle and positive inotropism.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10332R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10332R
Lokale Artikelnummer::
BOSSBS-10332R
Beschreibung:
This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. Nerve growth factor (NGF) is a peptide that plays a key role in the differentiation and survival of neurons in the peripheral nervous system (PNS) and the central nervous system (CNS). VGF is a peptide synthesized and secreted by neurons and is upregulated by NGF in the PC12 cell line. VGF is widely expressed in both the PNS and CNS, but is especially abundant in the adult hypothalamus. VGF plays an essential role in how the brain regulates energy expenditure and body weight. Its expression is rapidly induced by injury, the circadian clock, and neuronal activity.
VE:
1 * 100 µl
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