Horizontal+Gel+Electrophoresis+Systems
Artikel-Nr:
(BOSSBS-11963R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11963R-CY3
Lokale Artikelnummer::
BOSSBS-11963R-CY3
Beschreibung:
There are three SorCS genes that have diverse, partially overlapping functions in the central nervous system. In the developing and mature central nervous system, SorCS1, SorCS2 and SorCS3 genes are expressed in a combinatorial, non-overlapping pattern. SorCS proteins show homology to the mosaic receptor SorLA and the neurotensin receptor sortilin, based on a common VPS10 domain, which is the hallmark of the SorCS receptor family. SorCS2 (sortilin-related VPS10 domain containing receptor 2) is a 1,150 amino acid single-pass type I membrane protein that is highly expressed in brain and kidney. Containing six BNR repeats and a single PKD domain, SorCS2 is encoded by a gene that maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12056R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12056R-CY3
Lokale Artikelnummer::
BOSSBS-12056R-CY3
Beschreibung:
Serotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it is predominantly expressed in the gut, platelets and central nervous system (CNS). In the CNS, serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors. SR-3 is a ligand-gated ion channel, whereas all other known serotonin receptor subtypes are G protein-coupled receptors. SR-4 mediates widespread effects in central and peripheral nervous systems. SR-7 belongs to the superfamily of G protein-coupled receptors. The gene which encodes SR-7 maps to human chromosome 10q21-q24.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12056R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12056R-CY7
Lokale Artikelnummer::
BOSSBS-12056R-CY7
Beschreibung:
Serotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it is predominantly expressed in the gut, platelets and central nervous system (CNS). In the CNS, serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors. SR-3 is a ligand-gated ion channel, whereas all other known serotonin receptor subtypes are G protein-coupled receptors. SR-4 mediates widespread effects in central and peripheral nervous systems. SR-7 belongs to the superfamily of G protein-coupled receptors. The gene which encodes SR-7 maps to human chromosome 10q21-q24.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9632R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9632R-CY5
Lokale Artikelnummer::
BOSSBS-9632R-CY5
Beschreibung:
PDZD9 (PDZ domain containing 9) is a 264 amino acid protein that contains one PDZ (DHR) domain and participates in protein binding. Conserved in chimpanzee, dog, cow, mouse and rat, PDZD9 exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 16p12.1. Chromosome 16 encodes over 900 genes, approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. Giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth, and the rare disorder Rubinstein-Taybi syndrome, characterized by mental retardation and predisposition to tumor growth and white blood cell neoplasias, are associated with chromosome 16. Crohn's disease, a gastrointestinal inflammatory condition, and systemic lupus erythematosis are also associated with chromosome 16.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1206R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1206R-A647
Lokale Artikelnummer::
BOSSBS-1206R-A647
Beschreibung:
Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1206R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1206R-A750
Lokale Artikelnummer::
BOSSBS-1206R-A750
Beschreibung:
Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2366R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2366R-A647
Lokale Artikelnummer::
BOSSBS-2366R-A647
Beschreibung:
The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates. Involved in bile acid synthesis.
VE:
1 * 100 µl
Lieferant:
Merck
Beschreibung:
Histosec® pastilles (without DMSO) is an embedding medium for histology of samples of human origin. It is a paraffin enriched with polymers, also available with the addition of DMSO (dimethyl sulfoxide). DMSO increases the rate of penetration of paraffin and provides additional preservation of the tissue structures. Its melting range is between 56 - 58 °C and, within this range any specimen can be processed without fear of damage irrespective of the method used.
In most clinical laboratories the paraffinization is performed with an automated embedding system and is performed directly after the histoprocessing.
Lieferant:
Avantor Fluid Handling
Beschreibung:
Leistungsstarke, wartungsarme Antriebe sind vielseitig und kostengünstig.
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Artikel-Nr:
(BOSSBS-5220R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5220R-CY7
Lokale Artikelnummer::
BOSSBS-5220R-CY7
Beschreibung:
BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants (alpha and beta) produced by alternate splicing, differ in their C-terminal ends. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability. It appears to function in a feedback loop system with caspases. BCL2 inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF1). It can form homodimers, and heterodimers with BAX, BAD, BAK and BclX(L). Heterodimerization with BAX requires intact BH1 and BH2 domains, and is necessary for anti-apoptotic activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11890R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11890R
Lokale Artikelnummer::
BOSSBS-11890R
Beschreibung:
Monoamine oxidase A and B catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine. MAOB preferentially degrades benzylamine and phenylethylamine
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12548R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12548R-CY7
Lokale Artikelnummer::
BOSSBS-12548R-CY7
Beschreibung:
Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(630-3561)
Lieferant:
DISCOVER ECHO
Hersteller-Artikelnummer::
ECCG2230
Lokale Artikelnummer::
ECHLECCG2230
Beschreibung:
Bildgebung und Analyse lebender Zellen in Echtzeit innerhalb des Inkubators.
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-12333R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12333R
Lokale Artikelnummer::
BOSSBS-12333R
Beschreibung:
ERMAP is a single-pass type one membrane protein that belongs to the immunoglobulin superfamily. Expressed in cord blood, fetal liver and adult bone marrow, ERMAP is thought to function as a cell adhesion molecule in erythroid cells and is responsible for expression of the Scianna/Radin (Sc/Rd) blood group antigen system. The Sc/Rd system is comprised of seven antigens that are present on the surface of red blood cells and have a variety of functions ranging from protein transport to cell adhesion. These seven blood antigens can differ in their expression within a population and may sometimes differ between mother and child. A fetus expressing different blood antigens than its mother may cause the mother to produce against the fetal blood. This condition is known as hemolytic disease of the newborn (HDN) and is characterized by jaundice, anemia and in some cases, infant death.
VE:
1 * 100 µl
Artikel-Nr:
(93638-50MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
93638-50MG
Lokale Artikelnummer::
SUPL93638-50MG
Beschreibung:
Ethirimol ist das Ethylaminoisomer von Dimethirimol, das zu einer Gruppe von Pyrimidinfungiziden gehört. Dieses systemische Fungizid wirkt durch Hemmung der Nukleinsäuresynthese und wird als Saatgutbehandlung zur Bekämpfung von Mehltau in Sommergerste und Weizen eingesetzt. Ethirimol ist gemäß Verordnung (EG) Nr. 1107/2009 nicht zur Verwendung in der Europäischen Union (EU) zugelassen. Für Produkte pflanzlichen und tierischen Ursprungs gilt jedoch gemäß Verordnung (EU) 2021/1531 ein standardmäßiger Rückstandshöchstgehalt (MRL) von 0,01 bis 2 mg/kg. Ethirimol muss im mehrjährigen Kontrollprogramm für Pestizidrückstände (MACP) überwacht werden, das innerhalb der EU und der EFTA in/auf Produkten pflanzlichen Ursprungs durchgeführt wird.
VE:
1 * 50 mg
Lieferant:
S.C.A.T.
Beschreibung:
Die HPLC Versorgungs-Sets, V2.0 sind preisgünstige Gerätekombinationen zur kontaminationsfreien Versorgung von HPLC-Anlagen mit Lösungsmitteln. Die Sets bestehen jeweils aus einer Laborflasche mit GL 45-Gewinde, einer SCAT Safety Cap sowie passenden Kapillaren, Saugfiltern und Belüftungsventilen.
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