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4\\\\\\\'-Acetylbiphenyl-3-carbonsäure
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4\\\\\\\'-Acetylbiphenyl-3-carbonsäure
Artikel-Nr:
(BOSSBS-12498R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12498R-CY3
Lokale Artikelnummer::
BOSSBS-12498R-CY3
Beschreibung:
Apolipoproteins are protein components of plasma lipoproteins (1). The apolipoprotein L gene family encodes six highly homologous proteins designated apoL-I to -VI, which are associated with large high density type lipoproteins (HDL) (2,3). The human apoL family maps to chromosome 22q12.1-13.1 within a 127,000-bp region (4). ApoL has been characterized as a pancreas specific, 383-amino acid protein that contains a 12-amino acid secretory signal peptide (4). The apoL genes have TATA-less promoters and contain putative sterol regulatory elements, suggesting that transcription of these genes may be coordinated with that of the low density lipoprotein receptor and genes in pathways involving the synthesis of triglycerides and cholesterol (3). ApoL homologs can undergo 10 fold changes in expression during atherosclerotic changes in vascular endothelial cells, which includes the inflammatory reaction of atherosclerotic lesions (5).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5862R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5862R-CY5
Lokale Artikelnummer::
BOSSBS-5862R-CY5
Beschreibung:
ADAMTS (A Disintegrin And Metalloproteinase Domain with Thrombospondin type 1 Modules) is a family of zinc-dependent proteases that are implicated in a variety of normal and pathological conditions, including arthritis and cancer. ADAMTS protein family members contain an amino-terminal propeptide domain, a metalloproteinase domain, a disintegrin-like domain and a carboxy-terminus that contains a varying number of Thrombospondin type 1 (TSP-1) motifs. ADAMTS-L2 (ADAMTS-like protein 2) is a 951 amino acid secreted protein that is highly expressed in lung, kidney and liver. Mutations in the gene encoding ADAMTS are the cause of geleophysic dysplasia, an autosomal recessive disorder characterized by cardiac vavular anomalies, short stature, thick skin and brachydactyly. In individuals affected with geleophysic dysplasia, there is a significant increase in total active TGF-beta 1 and nuclear locations of p-SAMD2 in fibroblasts. Interestingly, ADAMTS-L2 interacts with LTBP-1, a glycoprotein that is part of the platelet-derived TGF-beta 1 complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7121R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7121R
Lokale Artikelnummer::
BOSSBS-7121R
Beschreibung:
The RAD23 gene of Saccharomyces cerevisiae is required for excision-repair of UV damaged DNA (1). RAD23 resembles the other DNA repair genes, RAD2, RAD6, RAD7, RAD18, and RAD54, all of which also exhibit increased transcription in response to DNA damage and during meiosis (2). RAD23 encodes a nuclear protein containing a ubiquitin-like domain required for biological function (3). RAD23 bears a ubiquitin-like domain at its amino terminus and this ubiquitin-like domain affects protein function in a nonproteolytic manner (3). Rad23 is a highly conserved protein involved in nucleotide excision repair (NER) that associates with the proteasome via its amino-terminus (4). Its carboxy-terminal ubiquitin-associated domain is evolutionarily conserved from yeast to humans (4). In addition to a role in DNA repair events in yeast, several lines of evidence indicate that the Rad23 protein may regulate the activity of the 26 S proteasome (5).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12497R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12497R-CY3
Lokale Artikelnummer::
BOSSBS-12497R-CY3
Beschreibung:
Apolipoproteins are protein components of plasma lipoproteins (1). The apolipoprotein C gene family encodes four homologous proteins designated apoC-I to -IV, which specifically modulate the metabolism of triglyceride-rich lipoproteins (2). The human apoC-I gene maps to chromosome 19q13.2 and is expressed primarily in the liver where it is activated when monocytes differentiate into macrophages (3,4). The human apoC-II gene maps to chromosome 19q13.2 and encodes a 79 amino acid single chain protein that is a necessary cofactor for the activation of lipoprotein lipase, the enzyme that hydrolyzes triglycerides in plasma and transfers the fatty acids to tissues (5–7). The human apoC-III gene maps to chromosome 11q23 and encodes a protein that may delay catabolism of triglyceride-rich particles by inhibiting lipoprotein lipase and hepatic lipase (8). The human apoC-IV gene maps to chromosome 19q13.2 and encodes a 127 amino acid protein that is primarily expressed in the liver (9,10).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3983R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3983R-A555
Lokale Artikelnummer::
BOSSBS-3983R-A555
Beschreibung:
Galactokinase is a major enzyme for the metabolism of galactose and its deficiency causes congenital cataracts in the adult population. GALK1 sequence shares the greatest level of conservation, 44.5% identity with that from E. coli and 34.6% amino acid identity with the product of the human GALK2 gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3983R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3983R-A750
Lokale Artikelnummer::
BOSSBS-3983R-A750
Beschreibung:
Galactokinase is a major enzyme for the metabolism of galactose and its deficiency causes congenital cataracts in the adult population. GALK1 sequence shares the greatest level of conservation, 44.5% identity with that from E. coli and 34.6% amino acid identity with the product of the human GALK2 gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3983R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3983R-A680
Lokale Artikelnummer::
BOSSBS-3983R-A680
Beschreibung:
Galactokinase is a major enzyme for the metabolism of galactose and its deficiency causes congenital cataracts in the adult population. GALK1 sequence shares the greatest level of conservation, 44.5% identity with that from E. coli and 34.6% amino acid identity with the product of the human GALK2 gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3919R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3919R-A680
Lokale Artikelnummer::
BOSSBS-3919R-A680
Beschreibung:
STARD5, or START domain containing 5, belongs to a family containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain. STARD5 may be involved in the intracellular transport of sterols or other lipids and may bind cholesterol or other sterols.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3215R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3215R-HRP
Lokale Artikelnummer::
BOSSBS-3215R-HRP
Beschreibung:
HDAC6 is a member of the class II mammalian histone deacetylases. Human HDAC6 is composed of 1215 amino acid residues. It possesses two separate putative catalytic domains. Both catalytic domains are fully functional HDACs and contribute independently to the overall activity of HDAC6 protein. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. The expression of HDAC6 is tightly linked to the state of cell differentiation. HDAC6 may participate in coordinating expression of a group of genes involved in the remodelling of chromatin during cell differentiation.
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR2235-250MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR2235-250MG
Lokale Artikelnummer::
APOSOR2235-250MG
Beschreibung:
(2S,4R)-4-Aminopyrrolidine-2-carboxylic acid, 4-BOC, N1-FMOC protected 97%
VE:
1 * 250 mg
Artikel-Nr:
(ACRO444580010)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
444580010
Lokale Artikelnummer::
ACRO444580010
Beschreibung:
2-Aminopyridine-4-boronic acid pinacol ester 97%
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-9015R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9015R-CY5.5
Lokale Artikelnummer::
BOSSBS-9015R-CY5.5
Beschreibung:
The EF-hand domain is a twelve amino acid loop motif that is commonly found in proteins that participate in calcium-binding events within the cell. EF-hand domains generally exist in a pair that, together, form a stable four-helix bundle that enables the binding of calcium ions. Swiprosin-2, also known as EFHD1 (EF-hand domain-containing protein D1), SWS2, PP3051 or MST133, is a 239 amino acid protein that contains two EF-hand domains and is expressed in a wide variety of tissues, including brain, liver, heart, kidney, testis, ovaries and spleen. Expression of Swiprosin-2, a possible calcium-binding protein, is upregulated during neuronal differentiation, suggesting a role for Swiprosin-2 in brain development and maturation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8237R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8237R-CY5.5
Lokale Artikelnummer::
BOSSBS-8237R-CY5.5
Beschreibung:
FERM domains are roughly 150 amino acids in length and are found in a number of cytoskeletal-associated proteins such as Ezrin, Radixin, Moesin and 4.1 (erythrocyte membrane protein band 4.1), where they provide a link between cytoskeletal signals and membrane dynamics. FRMD5 (FERM domain-containing protein 5) is a 570 amino acid single-pass membrane protein that contains one FERM domain and exists as two alternatively spliced isoforms. The gene encoding FRMD5 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8421R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8421R-A488
Lokale Artikelnummer::
BOSSBS-8421R-A488
Beschreibung:
BOLA1 (BolA-like protein 1), also known as CGI-143, is a member of the BolA/yrbA family of proteins. Members of this family are homologs of the Escherichia coli protein, BolA. BolA-like proteins are evolutionarily conserved from prokaryotes to eukaryotes and are believed to play a role in cell-cycle regulation or cell proliferation possibly via some sort of transcription regulation of other genes. In addition, BolA-like proteins may contain nucleic-acid binding properties, as is suggested by a fold structure that is similar to the KH-fold, a motif known to participate in nucleic-acid binding. Characteristic of BolA-like proteins which typically consist of approximately 100 amino acids, BOLA1 is a 137 amino acid protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9015R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9015R-A555
Lokale Artikelnummer::
BOSSBS-9015R-A555
Beschreibung:
The EF-hand domain is a twelve amino acid loop motif that is commonly found in proteins that participate in calcium-binding events within the cell. EF-hand domains generally exist in a pair that, together, form a stable four-helix bundle that enables the binding of calcium ions. Swiprosin-2, also known as EFHD1 (EF-hand domain-containing protein D1), SWS2, PP3051 or MST133, is a 239 amino acid protein that contains two EF-hand domains and is expressed in a wide variety of tissues, including brain, liver, heart, kidney, testis, ovaries and spleen. Expression of Swiprosin-2, a possible calcium-binding protein, is upregulated during neuronal differentiation, suggesting a role for Swiprosin-2 in brain development and maturation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13718R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13718R-HRP
Lokale Artikelnummer::
BOSSBS-13718R-HRP
Beschreibung:
Cadherins comprise a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino-terminus, which is characterised by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy-terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. Cadherin-26 is a 852 amino acid single-pass transmembrane protein containing 4 cadherin domains through which it interacts with other cadherins in a homophilic manner. There are 4 named isoforms of cadherin-26 that are produced as a result of alternative spicing events.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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