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K+LINE+LOGISTIS+(USA)+INC
Lieferant:
VWR Collection
Beschreibung:
Die VWR®-PPE-Kollektion Made in USA wurde nun mit SMS Laborkitteln erweitert.
Artikel-Nr:
(PRSI91-838)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-838
Lokale Artikelnummer::
PRSI91-838
Beschreibung:
ADAM DEC1 protein is expressed highly in the small intestine and appendix, moderately in lymph node, mucosal lining of the colon, thymus, spleen and very weakly in the bone marrow. ADAM DEC1 is induced during DC maturation and up-regulated in response to T-cell signals. It may play an important role in the control of the immune response and during pregnancy.
VE:
1 * 0,05 mg
New Product
Lieferant:
ProSci Inc.
Beschreibung:
CX3CR1 Antibody: CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, murine, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration and adhesion. CX3CR1 is expressed in a variety of human tissues and cell lines.
Artikel-Nr:
(PRSI96-089)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-089
Lokale Artikelnummer::
PRSI96-089
Beschreibung:
CD40 is also known as TNFRSF5, Bp50, CDW40, MGC9013, TNFRSF5 and p50, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins, and plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects. CD40 contains 4 cysteine-rich repeats in the extracellular domain, and is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines. The extracellular domain has the cysteinerich repeat regions, which are characteristic for many of the receptors of the TNF superfamily. Interaction of CD40 with its ligand, CD40L, leads to aggregation of CD40 molecules,which in turn interact with cytoplasmic components to initiate signaling pathways. Early studies on the CD40-CD40L system revealed its role in humoral immunity. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3), an autosomal recessive disorder characterized by an inability of B cells to undergo isotype switching, as well as an inability to mount an antibody-specific immune response, and a lack of germinal center formation.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(PRSI32-129)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
32-129
Lokale Artikelnummer::
PRSI32-129
Beschreibung:
The CD19 antigen (95 kDa) is expressed from the earliest stage of B progenitor development, on all peripheral B cells including germinal centre B cells, and all B cell lines and B cell leukaemia tested. T cell and monocytic cell lines are negative and the antigen is lost on B cell maturation to plasma cells. The antigen is a type I integral membrane glycoprotein whose in vitro inhibition will influence B cell activation and proliferation.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI28-402)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-402
Lokale Artikelnummer::
PRSI28-402
Beschreibung:
The ZNF2 gene is part of a sub-family of structurally related finger protein genes. Members of this sub-family are expressed as multiple transcripts in several cell lines.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI28-748)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-748
Lokale Artikelnummer::
PRSI28-748
Beschreibung:
KLF2/Lung Kruppel-like factor (LKLF) functions as a negative regulator of adipocyte differentiation. KLF2 is highly expressed in adipose tissue, and studies in cell lines and primary cells demonstrate that KLF2 is expressed in preadipocytes but not mature adipocytes.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI28-987)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-987
Lokale Artikelnummer::
PRSI28-987
Beschreibung:
RYBP contains 1 RanBP2-type zinc finger. RYBP may be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1. In tumor cell lines, it may induce apoptosis.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI28-031)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-031
Lokale Artikelnummer::
PRSI28-031
Beschreibung:
ASH2L plays a role in hematopoiesis and is associated with some special kinds of leukemia. The amount of ASH2L transcripts is extremely high in fetal liver, testis, and leukemia cell lines with erythroid and megakaryocytic potential.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI29-998)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-998
Lokale Artikelnummer::
PRSI29-998
Beschreibung:
GPNMB is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential.The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI33-481)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-481
Lokale Artikelnummer::
PRSI33-481
Beschreibung:
Recognises a protein of 74 kDa, identified as CD84 (Workshop V; Code A085, C057). It is expressed on mature B cells and on B-cell lines, including pre-B-cell lines, but not on plasma cell lines. Immunohistochemical studies demonstrated that CD84 strongly expressed on tissues macrophages. CD84 is also highly expressed on platelets and, at low levels on peripheral blood T cells. It is a highly N-glycosylated protein and belongs to immunoglobulin superfamily. It may play a role in leukocyte activation.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI79-745)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-745
Lokale Artikelnummer::
PRSI79-745
Beschreibung:
Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI28-706)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-706
Lokale Artikelnummer::
PRSI28-706
Beschreibung:
TRF3 is a nuclear protein that is present in all human and mouse tissues and cell lines examined.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI29-806)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-806
Lokale Artikelnummer::
PRSI29-806
Beschreibung:
Forkhead-box (FOX) transcription factors are implicated in carcinogenesis through gene amplification, retroviral integration, or chromosomal translocation. Human FOXN6 mRNA was expressed in breast cancer cell line and primary breast cancer.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI34-048)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
34-048
Lokale Artikelnummer::
PRSI34-048
Beschreibung:
EpCAM may act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. [UniProt].
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI26-962)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-962
Lokale Artikelnummer::
PRSI26-962
Beschreibung:
PDLIM3 contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, PDLIM3 has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle.
VE:
1 * 50 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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