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L(-)-Glutathion+(oxidierte+Form)
Artikel-Nr:
(BOSSBS-1398R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1398R-A647
Lokale Artikelnummer::
BOSSBS-1398R-A647
Beschreibung:
Stimulates transcription. Binds to purine-rich DNA sequences. Can form a ternary complex with the serum response factor and the ETS and SRF motifs of the fos serum response element.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7166R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7166R-A488
Lokale Artikelnummer::
BOSSBS-7166R-A488
Beschreibung:
Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7166R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7166R-A750
Lokale Artikelnummer::
BOSSBS-7166R-A750
Beschreibung:
Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11364R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11364R-CY7
Lokale Artikelnummer::
BOSSBS-11364R-CY7
Beschreibung:
The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13340R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13340R-A350
Lokale Artikelnummer::
BOSSBS-13340R-A350
Beschreibung:
Members of the mTERF family, including MTERF, MTERFD1, MTERFD2 and MTERFD3, are mitochondrial proteins that are believed to be transcription termination factors. MTERF (mitochondrial transcription termination factor 1) is composed of 399 amino acids and contains three leucine zippers that form a three-stranded coiled-coil that binds to DNA. It has been suggested that only the phosphorylated form of MTERF has transcription termination activity. MTERFD1 is also thought to act as a mitochondrial transcription regulator and is expressed as two isoforms produced by alternative splicing. MTERFD3 is believed to be involved in cell cycle regulation and cell growth by modulating mitochondrial transcription. MTERFD3 is expressed in heart, skeletal muscle, pancreas and liver.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5919R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5919R-A647
Lokale Artikelnummer::
BOSSBS-5919R-A647
Beschreibung:
Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorgenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9585R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9585R-CY3
Lokale Artikelnummer::
BOSSBS-9585R-CY3
Beschreibung:
Crystallins are water soluble structural proteins found in the vertebrate eye. Mammalian crystallins are classified in three forms, designated α, β and γ. Crystallins, as the principal components of the lens, function to increase the refractive index of the eye during accommodation by forming high-molecular weight aggregates which maintain transparency. γS-crystallin (Gamma-crystallin S), also known as Beta-crystallin S, is a 178 amino acid protein that exists as a monomer which does not aggregate. γS-crystallin contains a two-domain beta structure and belongs to the beta/gamma-crystallin gene family mapping to human chromosome 3. γS-crystallin has been linked to congenital cataract development, a disorder signified by increasing levels of lens opacity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5027R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5027R-HRP
Lokale Artikelnummer::
BOSSBS-5027R-HRP
Beschreibung:
Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity). In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11364R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11364R-CY5
Lokale Artikelnummer::
BOSSBS-11364R-CY5
Beschreibung:
The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5919R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5919R-HRP
Lokale Artikelnummer::
BOSSBS-5919R-HRP
Beschreibung:
Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorgenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5981R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5981R-CY5
Lokale Artikelnummer::
BOSSBS-5981R-CY5
Beschreibung:
p107 is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12033R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12033R
Lokale Artikelnummer::
BOSSBS-12033R
Beschreibung:
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of the structurally related subunits GluR-1 to -7, KA1 and KA2. KA1 (also designated EEA1) and KA2 (also designated EEA2) form heteromeric receptors with GluR subunits when coexpressed, forming ion channels with various properties. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11621R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11621R
Lokale Artikelnummer::
BOSSBS-11621R
Beschreibung:
The family of guanylin regulatory peptides, including guanylin and uroguanylin, are strongly expressed in intestinal mucosa and regulate intestinal fluid secretion during digestion. Guanylins are also involved in acid neutralization and the regulation of membrane-bound guanylate cyclase signaling molecules. Guanylin and uroguanylin are secreted primarily in the stomach, intestine, and colon. Guanylin is also detected in plasma. Guanylin is an endogenous activator of intestinal guanylate cyclase. It stimulates intestinal guanylate cyclase through the same receptor binding region as the heat-stable enterotoxins. Gut enterochromaffin cells synthesize guanylin to be a prohormone of 115 amino acids which is then is processed to the molecular form of 94 amino acids. This 10kDa form is found circulating in the blood.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4184R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4184R
Lokale Artikelnummer::
BOSSBS-4184R
Beschreibung:
p107 is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Lieferant:
Biosensis
Beschreibung:
The Biosensis ApoE/Aβ Complex ELISA kit is a sandwich ELISA that allows the preferential measurement of ApoE/Aβ complexes. This kit consists of a pre-coated mouse monoclonal anti-Aβ capture antibody, a highly validated ApoE/Aβ complex standard that is pre-formed, lyophilised and ready for reconstitution, a biotinylated ApoE detection antibody, and horseradish peroxidase (HRP)-conjugated streptavidin and detection reagent. The addition of a substrate (3,3’,5,5’-tetramethylbenzidine, TMB) yields a coloured reaction product which is directly proportional to the level of ApoE/Aβ complex present in samples and protein standards. Importantly, a well-characteriaed and unique ApoE/Aβ complex is included as a standard. This complex is pre-formed and lyophilised, requiring only reconstitution with assay diluent prior to use.
Artikel-Nr:
(90008.)
Lieferant:
Biotium
Hersteller-Artikelnummer::
90008
Lokale Artikelnummer::
BTIU90008
Beschreibung:
Free acid form of 6-TAMRA (6-carboxytetramethylrhodamine) single isomer. 6-Carboxytetramethylrhodamine, triethylammonium salt is a single isomer rhodamine dye. The 6-carboxy group can be activated to succinimidyl ester or mixed anhydride for coupling with amines using standard methods.
VE:
1 * 10 mg
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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