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Methyl+trans-3-hydroxycyclobutanecarboxylate
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Methyl+trans-3-hydroxycyclobutanecarboxylate
Artikel-Nr:
(BOSSBS-3354R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3354R-CY5
Lokale Artikelnummer::
BOSSBS-3354R-CY5
Beschreibung:
Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation. Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3354R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3354R-A488
Lokale Artikelnummer::
BOSSBS-3354R-A488
Beschreibung:
Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation. Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3354R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3354R-A647
Lokale Artikelnummer::
BOSSBS-3354R-A647
Beschreibung:
Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation. Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11997R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11997R-HRP
Lokale Artikelnummer::
BOSSBS-11997R-HRP
Beschreibung:
DDAH, a dimethylarginine dimethylaminohydrolase, hydrolyzes dimethyl arginine (ADMA) and monomethyl arginine (MMA), both inhibitors of nitric oxide synthases, and may be involved in in-vivo modulation of nitric oxide production (1,2). Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation (3). DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA) (4). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues (1).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2721R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2721R-A488
Lokale Artikelnummer::
BOSSBS-2721R-A488
Beschreibung:
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity). Interacts with MCMBP.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0268R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0268R-A350
Lokale Artikelnummer::
BOSSBS-0268R-A350
Beschreibung:
Neurobeachin binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. It may anchor the kinase to cytoskeletal and/or organelle-associated proteins. Neurobeachin, is also a neuron-specific multidomain protein of 327 kDa with a high-affinity binding site for the type II regulatory subunit of protein kinase A. Neurobeachin is peripherally associated with pleomorphic tubulovesicular endomembranes near the trans sides of Golgi stacks and throughout the cell body and cell processes. It is also found in a subpopulation of synapses, where it is concentrated at the postsynaptic plasma membrane.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0268R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0268R-A555
Lokale Artikelnummer::
BOSSBS-0268R-A555
Beschreibung:
Neurobeachin binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. It may anchor the kinase to cytoskeletal and/or organelle-associated proteins. Neurobeachin, is also a neuron-specific multidomain protein of 327 kDa with a high-affinity binding site for the type II regulatory subunit of protein kinase A. Neurobeachin is peripherally associated with pleomorphic tubulovesicular endomembranes near the trans sides of Golgi stacks and throughout the cell body and cell processes. It is also found in a subpopulation of synapses, where it is concentrated at the postsynaptic plasma membrane.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0268R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0268R
Lokale Artikelnummer::
BOSSBS-0268R
Beschreibung:
Neurobeachin binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. It may anchor the kinase to cytoskeletal and/or organelle-associated proteins. Neurobeachin, is also a neuron-specific multidomain protein of 327 kDa with a high-affinity binding site for the type II regulatory subunit of protein kinase A. Neurobeachin is peripherally associated with pleomorphic tubulovesicular endomembranes near the trans sides of Golgi stacks and throughout the cell body and cell processes. It is also found in a subpopulation of synapses, where it is concentrated at the postsynaptic plasma membrane.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3354R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3354R-A350
Lokale Artikelnummer::
BOSSBS-3354R-A350
Beschreibung:
Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation. Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12071R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12071R-CY5
Lokale Artikelnummer::
BOSSBS-12071R-CY5
Beschreibung:
P2Y purinoceptor 11 (P2Y11) is a 374 amino acid protein belonging to the G-protein coupled receptor one family. P2Y11 is a multi-pass cell membrane protein that acts as a receptor for both ATP and ATD coupled to G proteins. Due to these interactions, P2Y11 is involved in phosphatidylinositol-calcium and adenylyl cyclase pathways. Induced by DMSO and retinoic acid, P2Y11 is highly expressed in spleen tissue. A putative trans-splicing event involving the gene that encodes P2Y11 and an upstream gene encoding PPAN has been found to result in a fusion protein, designated PPAN-P2RY11.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
trans-3,4-Dichlor-β-nitrostyrol
Artikel-Nr:
(SIAL180548-1G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
180548-1G
Lokale Artikelnummer::
SIAL180548-1G
Beschreibung:
(2E,4E)-2,4-Heptadienal, Sigma-Aldrich®
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-11874R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11874R-A680
Lokale Artikelnummer::
BOSSBS-11874R-A680
Beschreibung:
Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T cells Signalling pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11874R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11874R-A647
Lokale Artikelnummer::
BOSSBS-11874R-A647
Beschreibung:
Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T cells signaling pathway.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
The human CD146 gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18, that belongs to the immunoglobulin superfamily and functions as a Ca2 -independent cell adhesion molecule. CD146 expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. CD146 is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Lieferant:
FLUOROCHEM
Beschreibung:
trans-3,3-Dimethyl-1-butenylboronsäure
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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