4-Oxohexahydrocyclopenta[c]pyrrole-2-carboxylic+acid+tert-butyl+e
Lieferant:
FLUOROCHEM
Beschreibung:
(E)-1-Penten-1,2-diboronsäurebis(pinakol)ester
Lieferant:
Alfa Aesar
Beschreibung:
Methylcholat ≥98%
Artikel-Nr:
(BLDPBD99199-100MG)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD99199-100MG
Lokale Artikelnummer::
BLDPBD99199-100MG
Beschreibung:
4-Methylumbelliferyl-alpha-D-galactopyranoside 98%
VE:
1 * 100 mg
Lieferant:
Sigma-Aldrich
Beschreibung:
EEDQ (Ethyl-N-(2-ethoxy-1,2-dihydrochinolin)carboxylat), Sigma-Aldrich®
Lieferant:
Biotium
Beschreibung:
This MAb reacts with an N-terminal epitope (aa 16-25) of both wild type and mutated p53. Mutation and/or allelic loss of p53 is one of the causes of a variety of mesenchymal and epithelial tumors. If it occurs in the germ line, such tumors run in families. In most transformed and tumor cells the concentration of p53 is increased 51000 fold over the minute concentrations (1000 molecules cell) in normal cells, principally due to the increased half-life (4 h) compared to that of the wild-type (20 min). p53 Localizes in the nucleus, but is detectable at the plasma membrane during mitosis and when certain mutations modulate cytoplasmic/nuclear distribution. Mutations arise with an average frequency of 70% but incidence varies from zero in carcinoid lung tumors to 97% in primary melanomas. High concentrations of p53 protein are transiently expressed in human epidermis and superficial dermal fibroblasts following mild ultraviolet irradiation. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia.
Lieferant:
Merck
Beschreibung:
EMSURE® grade solvents are suitable for a broad spectrum of classical lab applications, and are frequently used in regulated and highly demanding lab applications. EMSURE® provides worldwide best and most extensive product specifications. We declare our EMSURE® range to be in compliance with the ACS, with the reagent part of the European Pharmacopoeia (Reag. Ph Eur) and also with the ISO standards.
Artikel-Nr:
(MILLZSR240RXT0)
Lieferant:
Merck
Hersteller-Artikelnummer::
ZSR240RXT0
Lokale Artikelnummer::
MILLZSR240RXT0
Beschreibung:
Das Milli-Q® SR 240-Wasserreinigungssystem liefert reines Umkehrosmosewasser (RO) an einen mobilen SQ Switch 3,5-l-Tank. Es kann mit einem Schwerkraftventil (optional) ausgestattet werden, um reines RO-Wasser direkt aus dem SQ Switch-Tanksockel abzugeben.
VE:
1 * 1 ST
New Product
Artikel-Nr:
(BOSSBS-12478R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12478R-A647
Lokale Artikelnummer::
BOSSBS-12478R-A647
Beschreibung:
The Annexins constitute a family of structurally-related, relatively abundant proteins that exhibit Ca2+-dependent binding to phospholipids. Annexins function in multiple aspects of cell biology including regulation of membrane trafficking, transmembrane channel activity, inhibition of phospholipase A2, inhibition of coagulation and mediation of cell-matrix interactions. Annexin A13 is considered the original progenitor of the 12 members of vertebrate Annexins. The expression of Annexin A13 is highly tissue-specific, being expressed only in intestinal and kidney epithelial cells. This expression is associated with a highly differentiated intracellular transport function. Two alternative splicing isoforms of Annexin A13 exist, both of which bind to rafts.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15126R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15126R-FITC
Lokale Artikelnummer::
BOSSBS-15126R-FITC
Beschreibung:
The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukemias. C21orf59, also known as C21orf48, is a 290 amino acid protein and its gene product has been provisionally designated C21orf59 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12302R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12302R-A680
Lokale Artikelnummer::
BOSSBS-12302R-A680
Beschreibung:
PHC1 is a 1004 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex. Specifically, the PcG PRC1 complex modifies histones, remodels chromatin and mediates monoubiquination of Histone H2A. Other constituent proteins involved in the PcG PRC1 complex are Mel-18, Bmi-1, M33, MPc2, MPc3, RING1, Ring1b, as well as several others. Existing as a homodimer, PHC1 contains one FCS-type zinc finger and a SAM (sterile alpha motif) domain. PHC1 is encoded by a gene located on human chromosome 12, which encodes over 1100 genes and comprises approximately 4.5% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11098R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11098R-A647
Lokale Artikelnummer::
BOSSBS-11098R-A647
Beschreibung:
Neuroligins are a family of plasma membrane proteins that possess an N-terminal hydrophobic domain, a large esterase homology domain, a single transmembrane region, a short cytoplasmic domain, and an EF-hand binding domain (1,2). Members of the neuroligin family include Neuroligin 1, Neuroligin 2 and Neuroligin 3. Neuroligins are expressed in excitatory neuronal synaptic clefts. Neuroligins play a role in the formation and remodeling of CNS synapses by binding to b-neurexins, a family of neuronal cell surface proteins. Neuroexin 1b binds to the EF-hand domain of Neuroligin 1 and requires calcium ion. Neuroligins also bind to PSD-95, which may recruit ion channels and neurotransmitter receptors to the synapses.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10742R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10742R-A680
Lokale Artikelnummer::
BOSSBS-10742R-A680
Beschreibung:
Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-dependent. Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). Also converts lyso-PAF to 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine (PC), a major component of cell membranes and a PAF precursor. Under resting conditions, acyltransferase activity is preferred. Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases. Also catalyses the conversion of 1-acyl-sn-glycero-3-phosphocholine to 1,2-diacyl-sn-glycero-3-phosphocholine.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15126R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15126R-A750
Lokale Artikelnummer::
BOSSBS-15126R-A750
Beschreibung:
The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukemias. C21orf59, also known as C21orf48, is a 290 amino acid protein and its gene product has been provisionally designated C21orf59 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11098R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11098R-HRP
Lokale Artikelnummer::
BOSSBS-11098R-HRP
Beschreibung:
Neuroligins are a family of plasma membrane proteins that possess an N-terminal hydrophobic domain, a large esterase homology domain, a single transmembrane region, a short cytoplasmic domain, and an EF-hand binding domain (1,2). Members of the neuroligin family include Neuroligin 1, Neuroligin 2 and Neuroligin 3. Neuroligins are expressed in excitatory neuronal synaptic clefts. Neuroligins play a role in the formation and remodeling of CNS synapses by binding to b-neurexins, a family of neuronal cell surface proteins. Neuroexin 1b binds to the EF-hand domain of Neuroligin 1 and requires calcium ion. Neuroligins also bind to PSD-95, which may recruit ion channels and neurotransmitter receptors to the synapses.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12302R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12302R-A750
Lokale Artikelnummer::
BOSSBS-12302R-A750
Beschreibung:
PHC1 is a 1004 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex. Specifically, the PcG PRC1 complex modifies histones, remodels chromatin and mediates monoubiquination of Histone H2A. Other constituent proteins involved in the PcG PRC1 complex are Mel-18, Bmi-1, M33, MPc2, MPc3, RING1, Ring1b, as well as several others. Existing as a homodimer, PHC1 contains one FCS-type zinc finger and a SAM (sterile alpha motif) domain. PHC1 is encoded by a gene located on human chromosome 12, which encodes over 1100 genes and comprises approximately 4.5% of the human genome.
VE:
1 * 100 µl
Preis auf Anfrage
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