Naphthol+AS-BI-phosphat+Dinatriumsalz
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
3,5-Bis(trifluormethyl)benzamid 97%
Artikel-Nr:
(15139-250MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
15139-250MG
Lokale Artikelnummer::
SUPL15139-250MG
Beschreibung:
Bisphenol F bis(3-chloro-2-hydroxypropyl) ether a additive used during synthesis of organosol resin preventing theremal degradation of polymer. During the removal of hydrochloric acid in organosol resin results in this chlorinated compound.
VE:
1 * 250 mg
Artikel-Nr:
(BOSSBS-13476R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13476R-A350
Lokale Artikelnummer::
BOSSBS-13476R-A350
Beschreibung:
This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572). In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.[provided by RefSeq, May 2010].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13476R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13476R-HRP
Lokale Artikelnummer::
BOSSBS-13476R-HRP
Beschreibung:
This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572). In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.[provided by RefSeq, May 2010].
VE:
1 * 100 µl
Artikel-Nr:
(8.14689.0001)
Lieferant:
Merck
Hersteller-Artikelnummer::
8.14689.0001
Lokale Artikelnummer::
MERC8.14689.0001
Beschreibung:
Platin(II)acetylacetonat zur Synthese, Sigma-Aldrich®
VE:
1 * 1 g
Lieferant:
Alfa Aesar
Beschreibung:
Bis(methylthio)methan ≥99%
Artikel-Nr:
(BOSSBS-12462R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12462R-A750
Lokale Artikelnummer::
BOSSBS-12462R-A750
Beschreibung:
AGPS is a 658 amino acid enzyme that is required for glycerolipid metabolism and ether lipid biosynthesis. localised to the inner aspect of the peroxisomal membrane, AGPS is likely part of a heterotrimeric complex that is also composed of GNPAT and a modified form of GNPAT. Containing one FAD-binding PCMH-type domain, AGPS utilizes FAD as a cofactor in the synthesis of alkyl-glycerone 3-phophate and a long-chain acid anion from 1-acteyl-glyerone 3-phosphate and a long-chain alcohol. Defects in the gene encoding AGPS results in rhizomelic chondrodysplasia punctata type 3, a disease characterised by vertebral disorders, severe mental retardation, cutaneous lesions, cataracts and rhizomelic shortening of the humerus and femur.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11696R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11696R-FITC
Lokale Artikelnummer::
BOSSBS-11696R-FITC
Beschreibung:
The Huntingtin protein contains a polyglutamine region, which leads to Huntingtin’s disease (HD) when the number of glutamine repeats exceeds thirty-five. The mutated Huntingtin protein acts within the nucleus to induce neurodegeneration by a cell-specific apoptotic mechanism. The loss of activity of the Huntingtin protein may be contributed to abnormal interactions between the mutant protein and other associated cellular proteins. Huntingtin interacts with a variety of proteins including HAP1, glyceraldehyde phosphate dehydrogenase (GAPDH), HAP40, Rab5 and HIP1. HAP40 mediates the recruitment of Huntingtin by Rab5 onto early endosomes. Specifically, this complex regulates endosome motility, which may be a key event of the pathogenetic process leading to neurodegeneration in HD.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13507R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13507R-A488
Lokale Artikelnummer::
BOSSBS-13507R-A488
Beschreibung:
G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors and heptahelical receptors, are a protein family which interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates, and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. G protein receptor 84 (GPR84), a member of the GCPR 1 family, is an orphan GCPR expressed in bone marrow, brain, heart, muscle, colon, thymus, spleen, kidney, liver, placenta, intestine, lung and peripheral blood leukocytes. In activated T cells, GPR84 regulates early interleukin-4 (IL-4) gene expression.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8293R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8293R-A555
Lokale Artikelnummer::
BOSSBS-8293R-A555
Beschreibung:
DQX1 (DEAQ box RNA-dependent ATPase 1), also known as FLJ23757, is a 71 amino acid protein that contains one helicase ATP-binding domain and one helicase C-terminal domain. Localized to the nucleus, DQX1 catalyzes the conversion of ATP to ADP and a phosphate. Expressed as three isoforms produced by alternative splicing events, DQX1 is encoded by a gene that maps to human chomosome 2. As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2, including Harlequin icthyosis, sitosterolemia and Alstré°‰ syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8293R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8293R-A647
Lokale Artikelnummer::
BOSSBS-8293R-A647
Beschreibung:
DQX1 (DEAQ box RNA-dependent ATPase 1), also known as FLJ23757, is a 71 amino acid protein that contains one helicase ATP-binding domain and one helicase C-terminal domain. Localized to the nucleus, DQX1 catalyzes the conversion of ATP to ADP and a phosphate. Expressed as three isoforms produced by alternative splicing events, DQX1 is encoded by a gene that maps to human chomosome 2. As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2, including Harlequin icthyosis, sitosterolemia and Alstré°‰ syndrome.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Bis(4-chlorphenyl)sulfon 99%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1,1'-Bis(diphenylphosphino)ferrocen 99%
Artikel-Nr:
(BOSSBS-11708R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11708R-A488
Lokale Artikelnummer::
BOSSBS-11708R-A488
Beschreibung:
ATP13A2 is a 1,180 amino acid multi-pass membrane protein that belongs to the P5 subfamily of ATPases which play an important role in the transportation of inorganic cations. Expressed as multiple alternative spliced isoforms, ATP13A2 functions to catalyze the conversion of ATP to ADP and a free phosphate, thereby participating in the active transport of ions across cellular membranes. Defects in the gene encoding ATP13A2 are the cause of Kufor-Rakeb syndrome (KRS), a rare hereditary type of Parkinson’s disease that exhibits juvenile onset and is characterized by neurodegeneration and dementia. The ATP13A2 gene maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11696R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11696R-A488
Lokale Artikelnummer::
BOSSBS-11696R-A488
Beschreibung:
The Huntingtin protein contains a polyglutamine region, which leads to Huntingtin’s disease (HD) when the number of glutamine repeats exceeds thirty-five. The mutated Huntingtin protein acts within the nucleus to induce neurodegeneration by a cell-specific apoptotic mechanism. The loss of activity of the Huntingtin protein may be contributed to abnormal interactions between the mutant protein and other associated cellular proteins. Huntingtin interacts with a variety of proteins including HAP1, glyceraldehyde phosphate dehydrogenase (GAPDH), HAP40, Rab5 and HIP1. HAP40 mediates the recruitment of Huntingtin by Rab5 onto early endosomes. Specifically, this complex regulates endosome motility, which may be a key event of the pathogenetic process leading to neurodegeneration in HD.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9667R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9667R-FITC
Lokale Artikelnummer::
BOSSBS-9667R-FITC
Beschreibung:
DENND2C is a 928 amino acid protein that contains a dDENN domain, a DENN domain, and a uDENN domain and exists as three isoforms as a result of alternative splicing. The DENND2C protein is thought to target to actin filaments and control Rab9-dependent trafficking of mannose-6-phosphate receptor to lysosomes. The gene encoding DENND2C maps to human chromosome 1, the largest human chromosome which spans about 260 million base pairs and makes up 8% of the human genome. Other notable genes located on chromosome 1 include LMNA, which is associated with the rare aging disease Hutchinson-Gilford progeria, and the MUTYH gene, which is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome.
VE:
1 * 100 µl
Preis auf Anfrage
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