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1-Acetyl-2-naphthol
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1-Acetyl-2-naphthol
Artikel-Nr:
(BOSSBS-13536R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13536R-A488
Lokale Artikelnummer::
BOSSBS-13536R-A488
Beschreibung:
G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, PubMed:12711604, PubMed:23589301). Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. May play a role in glucose homeostasis by regulating the secretion of GLP-1, in response to short-chain fatty acids accumulating in the intestine. May also regulate the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake. Finally, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes. In parallel to its role in energy homeostasis, may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, regulating the rapid production of chemokines and cytokines. May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils. In addition to SCFAs, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13536R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13536R-A350
Lokale Artikelnummer::
BOSSBS-13536R-A350
Beschreibung:
G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, PubMed:12711604, PubMed:23589301). Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. May play a role in glucose homeostasis by regulating the secretion of GLP-1, in response to short-chain fatty acids accumulating in the intestine. May also regulate the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake. Finally, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes. In parallel to its role in energy homeostasis, may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, regulating the rapid production of chemokines and cytokines. May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils. In addition to SCFAs, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097).
VE:
1 * 100 µl
Lieferant:
Honeywell Chemicals
Beschreibung:
Alizarin-Komplexon ∼85% zur Erkennung von Fluor, Fluka™
Artikel-Nr:
(PRSI91-253)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-253
Lokale Artikelnummer::
PRSI91-253
Beschreibung:
Uroporphyrinogen decarboxylase (UROD), is an enzyme of the heme biosynthetic pathway which belongs to the uroporphyrinogen decarboxylase family. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. UROD is a homodimeric enzyme that catalyzes the fifth step in heme biosynthesis: the elimination of carboxyl groups from the four acetate side chains of uroporphyrinogen III to yield coproporphyrinogen III. Defects in UROD are the cause of familial porphyria cutanea tarda (FPCT) and hepatoerythropoietic porphyria (HEP).
VE:
1 * 50 µG
Lieferant:
MP Biomedicals
Beschreibung:
Tricine, a zwitterionic buffer, was first prepared by good for use as a buffer for chloroplast reactions. It is structurally similar to Tris, but is much less inhibitory at high concentrations. The name tricine comes from tris and glycine from which it was derived.
Artikel-Nr:
(BOSSBS-13536R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13536R-A680
Lokale Artikelnummer::
BOSSBS-13536R-A680
Beschreibung:
G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, PubMed:12711604, PubMed:23589301). Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. May play a role in glucose homeostasis by regulating the secretion of GLP-1, in response to short-chain fatty acids accumulating in the intestine. May also regulate the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake. Finally, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes. In parallel to its role in energy homeostasis, may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, regulating the rapid production of chemokines and cytokines. May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils. In addition to SCFAs, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097).
VE:
1 * 100 µl
Lieferant:
3M
Beschreibung:
Das nahezu unsichtbare Klebeband aus Zelluloseazetat ist ein essentielles Hilfsmittel im Büro, Zuhause oder im Labor. Ideal zum Reparieren und Versiegeln von Papier.
Lieferant:
Edwin Mraz Kunststoff-Erzeugnisse GmbH
Beschreibung:
PE, yellow coloured.
Artikel-Nr:
(PRSI92-376)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-376
Lokale Artikelnummer::
PRSI92-376
Beschreibung:
Matrix metallopeptidase 9 (MMP-9) is an enzyme encoded by the MMP9 gene. This protein, which is produced by normal alveolar macrophages and granulocytes, can be activated by 4-aminophenylmercuric acetate and phorbol ester and up-regulated by ARHGEF4, SPATA13 and APC via the JNK signalling pathway in colorectal tumour cells. MMP-9 is involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, angiogenesis, bone development, wound healling, cell migration, learning and memory, as well as in pathological processes, such as arthritis, intracerebral hemorrhage, and metastasis.
VE:
1 * 50 µG
Artikel-Nr:
(DALL1008112)
Lieferant:
HONEYWELL SAFETY
Hersteller-Artikelnummer::
1008112
Lokale Artikelnummer::
DALL1008112
Beschreibung:
Die schlagfeste Polycarbonat-Sichtscheibe bietet einen hervorragenden Schutz gegen fliegende Teilchen, grobe Stäube, Flüssigkeitsspritzer und -nebel.
VE:
1 * 1 ST
Artikel-Nr:
(SIAL374067-25G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
374067-25G
Lokale Artikelnummer::
SIAL374067-25G
Beschreibung:
Natriumchlordifluoracetat, Sigma-Aldrich®
VE:
1 * 25 g
Lieferant:
Bernd Kraft
Beschreibung:
pH Buffer solution, Acetat, pH-Wert: 5,50, Referenztemperatur: 20 °C, Farblos, Plastikflasche
Artikel-Nr:
(573100-100)
Lieferant:
Merck Millipore (Calbiochem)
Hersteller-Artikelnummer::
573100-100
Lokale Artikelnummer::
CALB573100-100
Beschreibung:
A useful agent for introducing thiol groups, in protected form, into various proteins. Reacts with primary amines to add protected sulfhydryl groups. When treated with hydroxylamine, yields a free sulfhydryl group that can be conjugated to maleimide-modified proteins.
VE:
1 * 100 mg
Lieferant:
MP Biomedicals
Beschreibung:
Electrophoresis Grade
Heavy metals (as Pb): 20 ppm
Used for preparation of Tris-glycine buffers.
Artikel-Nr:
(SPCME1040-500GM)
Lieferant:
Spectrum Chemical
Hersteller-Artikelnummer::
E1040-500GM
Lokale Artikelnummer::
SPCME1040-500GM
Beschreibung:
(Ethylenedinitrilo)tetraacetic Acid, Powder, Reagent, ACS, is generally abbreviated as EDTA, a colorless, water soluble aminopolycarboxylic acid and solid. It is used by many industries and in the laboratory for applications ranging from a sequestering agent to chelation therapy. As an ACS grade Reagent, this Spectrum Chemical manufactured compound is used as the quality standard against which other substances are graded and has met the toughest regulatory standards for quality and pureness.
VE:
1 * 500 g
Lieferant:
FLUOROCHEM
Beschreibung:
(±)-4-(Trifluormethyl)mandelsäure
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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