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Artikel-Nr:
(USBI130262)
Lieferant:
US Biological
Hersteller-Artikelnummer::
130262
Lokale Artikelnummer::
USBI130262
Beschreibung:
Anti-NEDD9 Mouse Monoclonal Antibody [clone: 1B4]
VE:
1 * 100 µG
Lieferant:
Brand
Beschreibung:
Flexible Entladungsröhre mit Rückführventil, PTFE, gewickelt, Länge ca. 800 mm, mit Sicherheitsgriff, für Dispensette® S/S Organic 2,5 +10 ml (nicht geeignet für Flusssäure)
Artikel-Nr:
(BOSSBS-0080R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0080R-A350
Lokale Artikelnummer::
BOSSBS-0080R-A350
Beschreibung:
B lymphocytes marker CD20 is a non glycosylated protein with a molecular weight of 35 or 37 kDa depending on the degree of phosphorylation. Although not a member of the tetraspanin superfamily of cell surface receptors, it crosses the cell membrane four times. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0080R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0080R-A647
Lokale Artikelnummer::
BOSSBS-0080R-A647
Beschreibung:
B lymphocytes marker CD20 is a non glycosylated protein with a molecular weight of 35 or 37 kDa depending on the degree of phosphorylation. Although not a member of the tetraspanin superfamily of cell surface receptors, it crosses the cell membrane four times. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6253R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6253R-A350
Lokale Artikelnummer::
BOSSBS-6253R-A350
Beschreibung:
The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Seven transcript variants encoding six distinct isoforms have been identified for this gene. Additional splice variants have been described but their full-length nature has not been determined. The identified isoforms exhibit a distinct ability to undergo autophosphorylation and to phosphorylate the downstream kinases. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11466R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11466R-CY5
Lokale Artikelnummer::
BOSSBS-11466R-CY5
Beschreibung:
Cell surface protein involved in cell-cell-interactions, exocytosis of secretory granules and regulation of signal transmission. Function is isoform-specific. Alpha-type isoforms have a long N-terminus with six laminin G-like domains and play an important role in synaptic signal transmission. Alpha-type isoforms play a role in the regulation of calcium channel activity and Ca(2+)-triggered neurotransmitter release at synapses and at neuromuscular junctions. They play an important role in Ca(2+)-triggered exocytosis of secretory granules in pituitary gland. They may effect their functions at synapses and in endocrine cells via their interactions with proteins from the exocytotic machinery. Likewise, alpha-type isoforms play a role in regulating the activity of postsynaptic NMDA receptors, a subtype of glutamate-gated ion channels. Both alpha-type and beta-type isoforms may play a role in the formation or maintenance of synaptic junctions via their calcium-dependent interactions (via the extracellular domains) with neuroligin family members, CBLN1 or CBLN2. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Alpha-type isoforms were first identified as receptors for alpha-latrotoxin from spider venom (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5422R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5422R-A555
Lokale Artikelnummer::
BOSSBS-5422R-A555
Beschreibung:
Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. The protein is involved in regulation of ionic conductances and long term synaptic plasticity. It may play an important role in dephosphorylating substrates such as the postsynaptic density associated Ca (2+)/calmodulin dependent protein kinase II.PP1 comprises a catalytic subunit, PPP1CA, PPP1CB or PPP1CC (PP1C gamma), which is folded into its native form by inhibitor 2 and glycogen synthetase kinase 3, and then complexed to one or several targeting or regulatory subunits. PPP1R12A and PPP1R12B mediate binding to myosin. PPP1R3A, PPP1R3B, PPP1R3C and PPP1R3D mediate binding to glycogen.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5422R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5422R-CY5
Lokale Artikelnummer::
BOSSBS-5422R-CY5
Beschreibung:
Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. The protein is involved in regulation of ionic conductances and long term synaptic plasticity. It may play an important role in dephosphorylating substrates such as the postsynaptic density associated Ca (2+)/calmodulin dependent protein kinase II.PP1 comprises a catalytic subunit, PPP1CA, PPP1CB or PPP1CC (PP1C gamma), which is folded into its native form by inhibitor 2 and glycogen synthetase kinase 3, and then complexed to one or several targeting or regulatory subunits. PPP1R12A and PPP1R12B mediate binding to myosin. PPP1R3A, PPP1R3B, PPP1R3C and PPP1R3D mediate binding to glycogen.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13633R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13633R-CY5
Lokale Artikelnummer::
BOSSBS-13633R-CY5
Beschreibung:
The downstream of kinase family (Dok1-7) are members of a class of “docking†proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Based on their similarities, the Dok family of proteins can be divided into three subgroups: Dok-1/2/3, Dok-4/5/6 and Dok-7. Through its interaction with muscle-specific receptor kinase (MuSK), Dok-7 is crucial for neuromuscular synaptogenesis and for MuSK activation. Mice lacking Dok-7 do not form neuromuscular synapses nor acetylcholine receptor clusters. Mutations in the Dok-7 gene can cause congenital myasthenic syndromes (CMA) — recessively inherited disorders characterized by muscle weakness.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13715R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13715R-A680
Lokale Artikelnummer::
BOSSBS-13715R-A680
Beschreibung:
The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morpho-genesis (1-4). Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity (5,6). The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including catenin b, to regulate cadherin function (7). BR-cadherin (for brain-cadherin, also designated cadherin-12 or N-cadherin 2) is expressed specifically in neurons in the central nervous system and is thought to be involved in neuronal development (8).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13633R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13633R
Lokale Artikelnummer::
BOSSBS-13633R
Beschreibung:
The downstream of kinase family (Dok1-7) are members of a class of “docking†proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Based on their similarities, the Dok family of proteins can be divided into three subgroups: Dok-1/2/3, Dok-4/5/6 and Dok-7. Through its interaction with muscle-specific receptor kinase (MuSK), Dok-7 is crucial for neuromuscular synaptogenesis and for MuSK activation. Mice lacking Dok-7 do not form neuromuscular synapses nor acetylcholine receptor clusters. Mutations in the Dok-7 gene can cause congenital myasthenic syndromes (CMA) — recessively inherited disorders characterized by muscle weakness.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9441R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9441R-A750
Lokale Artikelnummer::
BOSSBS-9441R-A750
Beschreibung:
The downstream regulatory element, DRE, acts as a location-dependent gene silencer. DREAM (for DRE-antagonist modulator) is a Ca²⁺ regulated transcriptional repressor that specifically binds to the DRE. DREAM regulates transcription of prodynorphin and c-Fos genes and shows 99% nucleotide homology to the Kv channel-interacting proteins (KChIPs). KChIP family members include KChIP1, which is expressed in brain, KChIP2, which is expressed in heart, brain, and lung, KChIP3 (also designated calsenilin), which is expressed in brain and testis and KChIP4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9441R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9441R-A680
Lokale Artikelnummer::
BOSSBS-9441R-A680
Beschreibung:
The downstream regulatory element, DRE, acts as a location-dependent gene silencer. DREAM (for DRE-antagonist modulator) is a Ca²⁺ regulated transcriptional repressor that specifically binds to the DRE. DREAM regulates transcription of prodynorphin and c-Fos genes and shows 99% nucleotide homology to the Kv channel-interacting proteins (KChIPs). KChIP family members include KChIP1, which is expressed in brain, KChIP2, which is expressed in heart, brain, and lung, KChIP3 (also designated calsenilin), which is expressed in brain and testis and KChIP4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6516R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6516R-CY5
Lokale Artikelnummer::
BOSSBS-6516R-CY5
Beschreibung:
The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10757R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10757R-A750
Lokale Artikelnummer::
BOSSBS-10757R-A750
Beschreibung:
Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src Signalling pathways. May be involved in neuronal NGF-dependent Ca²⁺ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalisation and recycling of mu-type opioid receptor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6516R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6516R-A488
Lokale Artikelnummer::
BOSSBS-6516R-A488
Beschreibung:
The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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