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3-(3-Hydroxy-phenyl)-acrylic+acid+ethyl+ester
Artikel-Nr:
(PRSI96-167)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-167
Lokale Artikelnummer::
PRSI96-167
Beschreibung:
CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.
VE:
1 * 100 µG
Artikel-Nr:
(STMC100-1394)
Lieferant:
Stemcell Technologies
Hersteller-Artikelnummer::
100-1394
Lokale Artikelnummer::
STMC100-1394
Beschreibung:
Stimulating T cells with HPV16 (E7) Peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. HPV16 (E7) Peptide pool is a lyophilised mixture of 22 peptides from protein E7 of human papillomavirus type 16 (HPV16) consisting of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 98 on protein E7. E7 is an oncoprotein that binds and mediates degradation of the retinoblastoma tumor suppressor protein pRB (Gonzalez <i>et al.</i>). E7 together with E6 demonstrated the ability to immortalize human keratinocytes in vitro, which likely has significance for HPVs oncogenic potential (Hawley-Nelson <i>et al.</i>). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
VE:
1 * 1 LE
New Product
 This is a MarketSource item. Additional charges may apply
Lieferant:
LAUDA
Beschreibung:
Brückenthermostate mit einfachem Sensorbedienfeld und variabler Varioflex-Pumpe; Die Modelle PB besitzen eine Druck-/Saugpumpe. Die Modelle PBD sind mit einer stärkeren Druckpumpe mit 8 wählbaren, auf den jeweiligen Leistungsbedarf anpassbaren Stufen bis 1,1 bar und einer Pumpleistung (Druck) von maximal 32 L/min ausgestattet und ermöglichen die Temperierung von tieferen Bädern bis 320 mm. Teleskopstange für Bäder mit einer Breite von 310 bis 550 mm, ergonomischer Griff und rückseitige und seitliche Pumpenanschlüsse.
Artikel-Nr:
(HONC443808-20L)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
443808-20L
Lokale Artikelnummer::
HONC443808-20L
Beschreibung:
ACS GENERAL USE SOLVENTS
VE:
1 * 20 L
Artikel-Nr:
(PRSI92-441)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-441
Lokale Artikelnummer::
PRSI92-441
Beschreibung:
Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. The p19 subunit has homology to the p35 subunit of IL-12, as well as to other single chain cytokines such as IL-6 and IL-11. The p40 subunit is homologous to the extracellular domains of the hematopoietic cytokine receptors. Although p19 is expressed by activated macrophages, dendritic cells, T cells, and endothelial cells, only activated macrophages and dendritic cells express p40 concurrently to produce IL-23. IL-23 has biological activities that are similar to, but distinct from IL-12. Both IL-12 and IL-23 induce proliferation and IFN-gamma production by human T cells. While IL-12 acts on both naive and memory human T cells, the effects of IL-23 is restricted to memory T cells.
VE:
1 * 50 µG
Artikel-Nr:
(SIAL17480-25G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
17480-25G
Lokale Artikelnummer::
SIAL17480-25G
Beschreibung:
Bromkresolgrün Natriumsalz, Sigma-Aldrich®
VE:
1 * 25 g
Artikel-Nr:
(STMC100-1397)
Lieferant:
Stemcell Technologies
Hersteller-Artikelnummer::
100-1397
Lokale Artikelnummer::
STMC100-1397
Beschreibung:
Stimulating T cells with HPV18 (L2) peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. A lyophilised mixture of 113 peptides from minor capsid protein L2 of human papillomavirus type 18 (HPV18), HPV18 (L2) peptide pool consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 462 on L2. With two nuclear localization signals, L2 may enter the nuclei of host cells via several import pathways mediated by Kap α2β1 heterodimers, Kap β2, and Kap β (Klucevsek <i>et al.</i>). L2 can also assemble into virus-like particles, and may have a role in encapsidation (Stauffer <i>et al.</i>). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
VE:
1 * 1 LE
New Product
This is a MarketSource item. Additional charges may apply
Lieferant:
Honeywell Chemicals
Beschreibung:
tert-Butylmethylether ≥99,5% (durch GC), Puriss. p.a., Riedel-de Haën™
Lieferant:
Honeywell Chemicals
Beschreibung:
tert-Butylmethylether ≥99,8%, CHROMASOLV™ für die HPLC, Riedel-de Haën™
Artikel-Nr:
(STMC100-1409)
Lieferant:
Stemcell Technologies
Hersteller-Artikelnummer::
100-1409
Lokale Artikelnummer::
STMC100-1409
Beschreibung:
Stimulating T cells with VZV (IE63) peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. VZV (IE63) peptide pool is a lyophilised mixture of 67 peptides from the transcriptional regulator ICP22 homolog (IE63) of Varicella-zoster virus (VZV; strain Oka vaccine), and consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 278 on IE63. Expressed during VZV latency and reactivation (Lungu <i>et al.</i>), IE63 demonstrates repressive activity in both the cytoplasm and nucleus of infected cells (Bontems <i>et al.</i>). Host interferon alpha (IFN-α) activity is inhibited by VZV IE63, which likely contributes to VZV pathogenesis (Ambagala and Cohen). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
VE:
1 * 1 LE
New Product
This is a MarketSource item. Additional charges may apply
Lieferant:
Sigma-Aldrich
Beschreibung:
di-Kaliumhydrogenphosphat 1 mol/l in wässriger Lösung, Sigma-Aldrich®
Artikel-Nr:
(UPTIUP15426D)
Lieferant:
Uptima
Hersteller-Artikelnummer::
UP15426D
Lokale Artikelnummer::
UPTIUP15426D
Beschreibung:
3,3',5,5'-Tetramethylbenzidin (TMB), Pulver, ultrarein
VE:
1 * 1 g
Artikel-Nr:
(STMC100-1398)
Lieferant:
Stemcell Technologies
Hersteller-Artikelnummer::
100-1398
Lokale Artikelnummer::
STMC100-1398
Beschreibung:
Stimulating T cells with BKV (LT) Peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. BKV Peptide pool is a lyophilised mixture of 171 peptides from the Large T (LT) antigen of BK polyomavirus (BKV), and consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 695 on LT antigen. LT antigen is an early viral protein (Low <i>et al.</i>) that contributes to the transformation and maintenance of host cells (Nakshatri <i>et al.</i>). It has been found to bind to a subset of tumor suppressor proteins (Harris <i>et al.</i>), and its co-expression with p53 has been observed in polyomavirus-associated nephropathy (Seemayer <i>et al.</i>). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
VE:
1 * 1 LE
New Product
This is a MarketSource item. Additional charges may apply
Lieferant:
SARSTEDT
Beschreibung:
The blood gas Monovette® is available in 1 ml and 2 ml options for venous and arterial blood collection.
Artikel-Nr:
(PRSI25-504)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-504
Lokale Artikelnummer::
PRSI25-504
Beschreibung:
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC5, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants have been described for HOXC5. The transcript variant which includes the shared exon apparently doesn't encode a protein. The protein-coding transcript variant contains gene-specific exons only.This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC5, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants have been described for HOXC5. The transcript variant which includes the shared exon apparently doesn't encode a protein. The protein-coding transcript variant contains gene-specific exons only.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI96-171)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-171
Lokale Artikelnummer::
PRSI96-171
Beschreibung:
CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.
VE:
1 * 100 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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