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Sulbactam+sodium
Artikel-Nr:
(BOSSBS-12313R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12313R
Lokale Artikelnummer::
BOSSBS-12313R
Beschreibung:
The PHEX a 749 amino acid protein that putatively consists of an intracellular, transmembrane and extracellular domain. PHEX mutations have been observed in 60-80% of hypophosphatemic rickets patients. The PHEX protein, which is a single-pass membrane protein, is also designated HYP, X-linked hypophosphatemia protein or metalloendopeptidase homolog PEX. PHEX plays an active role in bone and dentin mineralization and renal phosphate re-absorption. X-linked hypophosphatemic rickets, also designated HYP, is an X-linked dominant disorder characterized by impaired phosphate uptake in the kidney, which is likely to be caused by abnormal regulation of sodium phosphate cotransport in the proximal tubules. Clinical manifestations include skeletal deformities, growth failure, craniosynostosis, paravertebral calcifications, pseudofractures in lower extremities, and muscular hypotonia with onset in early childhood.
VE:
1 * 100 µl
Artikel-Nr:
(J60887.MC)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
J60887.MC
Lokale Artikelnummer::
ALFAJ60887.MC
Beschreibung:
Dantrolene sodium salt
VE:
1 * 100 mg
Lieferant:
MP Biomedicals
Beschreibung:
Sodium Valproate is reported to cause inositol depletion, activate the ERK pathway, inhibit GSK-3α and GSK-3β. Valproic Acid has been reported to be a potent inhibitor of HDAC (histone deacetylase) in vitro (IC50 = 400 μM for HDAC1), thereby relieving HDAC-dependent transcriptional repression and causes the hyperacetylation of histones in cultured cells.
Artikel-Nr:
(BOSSBS-12313R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12313R-A647
Lokale Artikelnummer::
BOSSBS-12313R-A647
Beschreibung:
The PHEX a 749 amino acid protein that putatively consists of an intracellular, transmembrane and extracellular domain. PHEX mutations have been observed in 60-80% of hypophosphatemic rickets patients. The PHEX protein, which is a single-pass membrane protein, is also designated HYP, X-linked hypophosphatemia protein or metalloendopeptidase homolog PEX. PHEX plays an active role in bone and dentin mineralization and renal phosphate re-absorption. X-linked hypophosphatemic rickets, also designated HYP, is an X-linked dominant disorder characterized by impaired phosphate uptake in the kidney, which is likely to be caused by abnormal regulation of sodium phosphate cotransport in the proximal tubules. Clinical manifestations include skeletal deformities, growth failure, craniosynostosis, paravertebral calcifications, pseudofractures in lower extremities, and muscular hypotonia with onset in early childhood.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12313R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12313R-HRP
Lokale Artikelnummer::
BOSSBS-12313R-HRP
Beschreibung:
The PHEX a 749 amino acid protein that putatively consists of an intracellular, transmembrane and extracellular domain. PHEX mutations have been observed in 60-80% of hypophosphatemic rickets patients. The PHEX protein, which is a single-pass membrane protein, is also designated HYP, X-linked hypophosphatemia protein or metalloendopeptidase homolog PEX. PHEX plays an active role in bone and dentin mineralization and renal phosphate re-absorption. X-linked hypophosphatemic rickets, also designated HYP, is an X-linked dominant disorder characterized by impaired phosphate uptake in the kidney, which is likely to be caused by abnormal regulation of sodium phosphate cotransport in the proximal tubules. Clinical manifestations include skeletal deformities, growth failure, craniosynostosis, paravertebral calcifications, pseudofractures in lower extremities, and muscular hypotonia with onset in early childhood.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11954R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11954R
Lokale Artikelnummer::
BOSSBS-11954R
Beschreibung:
Myo-inositol is involved in many important aspects of cellular regulation including membrane structure, signal transduction and osmoregulation. It is taken up into cells by the sodium/myo-inositol cotransporter (SMIT). SMIT activity maintains intracellular concentrations of myo-inositol; it is upregulated in response to hypertonic stress. The human SMIT protein is encoded by the SLC5A3 gene, which maps to chromosome 21q22.12. It is expressed in many human tissues, such as brain, kidney and placenta. Specifically, SMIT is abundantly expressed throughout the whole brain and spinal cord in fetal rat, but is downregulated in adult rat brain with the exception of the choroid plexus, where SMIT expression remains high. In kidney, SMIT localizes to the baso-lateral membranes of the thick ascending limb of Henle (TAL) and the inner medullary collecting duct (IMCD). Impaired SMIT activity is implicated in the pathogenesis of diabetes and Down syndrome.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
Chondroitin sulphate sodium salt
Artikel-Nr:
(HONE04267.9025)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
04267.9025
Lokale Artikelnummer::
HONE04267.9025
Beschreibung:
Sodium hexametaphosphate
VE:
1 * 25 kg
Artikel-Nr:
(ICNA0215196901)
Lieferant:
MP Biomedicals
Hersteller-Artikelnummer::
0215196901
Lokale Artikelnummer::
ICNA0215196901
Beschreibung:
PGI2 is synthesized primarily in vascular endothelial cells. It is a potent inhibitor of platelet aggregation, relaxes vascular smooth muscle, and also increases cyclic AMP concentration in human platelets.
VE:
1 * 1 mg
Lieferant:
Thermo Scientific
Beschreibung:
Sodium hexacyanoferrate(II) decahydrate
Artikel-Nr:
(USBI167509)
Lieferant:
US Biological
Hersteller-Artikelnummer::
167509
Lokale Artikelnummer::
USBI167509
Beschreibung:
Anti-SLC8A3 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-3348R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3348R-CY3
Lokale Artikelnummer::
BOSSBS-3348R-CY3
Beschreibung:
PSD 93 is believed to participate in the clustering of certain proteins, including N-methyl-D-aspartate (NMDA) receptors and shaker-type potassium channels at the synaptic membrane. There are two principal modes of interaction between PSD 93 and other proteins. NMDA receptors and shaker-type potassium channels both share C-terminal sequence homology consisting of a threonine/serine-X-valine-COOH (T/SXV) motif. Other neuronal proteins that share this motif (beta 1 adrenergic receptor, some serotonin receptors, some sodium channel subunits, and additional potassium channel subunits) may interact with PSD 93 by binding to its PDZ domains. Neuronal nitric oxide synthase (nNOS), which lacks the T/SXV motif but which has its own PDZ domain, has been shown to associate with PSD 93 in vitro through a pseudo-homotypic PDZ-PDZ interaction.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11954R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11954R-A555
Lokale Artikelnummer::
BOSSBS-11954R-A555
Beschreibung:
Myo-inositol is involved in many important aspects of cellular regulation including membrane structure, signal transduction and osmoregulation. It is taken up into cells by the sodium/myo-inositol cotransporter (SMIT). SMIT activity maintains intracellular concentrations of myo-inositol; it is upregulated in response to hypertonic stress. The human SMIT protein is encoded by the SLC5A3 gene, which maps to chromosome 21q22.12. It is expressed in many human tissues, such as brain, kidney and placenta. Specifically, SMIT is abundantly expressed throughout the whole brain and spinal cord in fetal rat, but is downregulated in adult rat brain with the exception of the choroid plexus, where SMIT expression remains high. In kidney, SMIT localizes to the baso-lateral membranes of the thick ascending limb of Henle (TAL) and the inner medullary collecting duct (IMCD). Impaired SMIT activity is implicated in the pathogenesis of diabetes and Down syndrome.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
Pantoprazole sodium salt hydrate
Artikel-Nr:
(BOSSBS-9045R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9045R-A750
Lokale Artikelnummer::
BOSSBS-9045R-A750
Beschreibung:
Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarisation, changes in temperature resulting in graded shifts of its voltage-dependent activation curves. The chemical agonists menthol functions as a gating modifier, shifting activation curves towards physiological membrane potentials. Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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