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cis-1,2,3,6-Tetrahydrophthalimide


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Lieferant:  Honeywell Chemicals
Hersteller-Artikelnummer:: 32751-100G
Lokale Artikelnummer:: HONC32751-100G
Beschreibung:   Eriochromschwarz T Reag. Ph. Eur. Indikator für die Metalltitration, Fluka™
VE:  1 * 100 g

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 79-710
Lokale Artikelnummer:: PRSI79-710
Beschreibung:   Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3'. In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally discribed as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
VE:  1 * 100 µG
Lieferant:  MP Biomedicals
Beschreibung:   Storage: Store at Room Temperature (15-30 °C).
D-myo-Inositol is a component of membrane phospholipids, glycosylphophatidylinositol anchors that bind glycoproteins to cell membranes, and inositol phosphate second messengers. It is a growth factor for animals as well as microorganisms. Myo-Inositol is the most abundant form of polyols that serves as a structural element of secondary messengers in eukaryotic cells. Inositol or cyclohexane-1,2,3,4,5,6-hexol is a chemical compound, a sixfold alcohol (polyol) of cyclohexane. It exists in nine possible stereoisomers, of which the most prominent form, widely occurring in nature, is cis-1,2,3,5-trans-4,6-cyclohexanehexol, or myo-inositol (former name meso-inositol). Inositol is a carbohydrate, though not a classical sugar. It has a taste which has been assayed at half the sweetness of table sugar. Used as a lipotropic agent.
A component of membrane phospholipids, glycosyl­phosphatidyl­inositol anchors that bind glycoproteins to cell membranes, and inositol phosphate second messengers. In addition, inositol serves as an important component of the structural lipids phosphatidylinositol (PI) and its various phosphates, the phosphatidylinositol phosphate (PIP) lipids.
Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 33-371
Lokale Artikelnummer:: PRSI33-371
Beschreibung:   This mAb recognises a protein of 134 kDa, which binds fibroblast growth factor and E-selectin (cell-adhesion lectin on endothelial cells mediating the binding of neutrophils). Fucosylation is essential for binding to E-selectin. It contains sialic acid residues and 16 Cys-rich GLG1 repeats. This mAb can be used to stain the Golgi complex in cell or tissue preparations and can be used as a Golgi marker in subcellular fractions. It produces a diffuse staining pattern of the Golgi zone in normal and malignant cells. This mAb is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells. The Golgi apparatus is an organelle present in all eukaryotic cells that forms a part of the endomembrane system. The primary function of the Golgi apparatus is to process and package macromolecules synthesised by the cell for exocytosis or use within the cell. The Golgi is made up of a stack of flattened, membrane-bound sacs known as cisternae, with three functional regions: the cis face, medial region and trans face. Each region consists of various enzymes that selectively modify the macromolecules passing though them, depending on where they are destined to reside. Several spherical vesicles that have budded off of the Golgi are present surrounding the main cisternae. The Golgi tends to be more pronounced and numerous in cells that make and secrete many substances such as plasma B cells.
VE:  1 * 100 µG
Lieferant:  Abcam
Beschreibung:   Anti-GM130 Rabbit Monoclonal Antibody [clone: EP892Y] (Alexa Fluor® 750)
VE:  1 * 100 µl
New Product
Artikel-Nr: (EHERC11870000)

Lieferant:  EHRENSTORFER
Hersteller-Artikelnummer:: C11870000
Lokale Artikelnummer:: EHERC11870000
Beschreibung:   Cyhexatin
VE:  1 * 0,25 g
Lieferant:  Spectrum Chemical
Beschreibung:   Polysorbate 80, FCC is used as a wetting agent. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
Artikel-Nr: (PRSI92-485)

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 92-485
Lokale Artikelnummer:: PRSI92-485
Beschreibung:   Mouse ULBP1, also known as RAET1I and NKG2DL1, is a member of the ULBP/RAET1 gene family. ULBP1 plays an important role in immune responses, especially in cancer and infectious diseases, and is well-known to bind to NKG2D together with at least ULBP 2 and 3. These proteins are distantly related to major histocompatibility class I (MHC I) molecules, possessing the alpha 1 and alpha 2 Ig-like domains, but lacking the alpha 3 domain. Unlike MHC Class I, they have no capacity to bind peptide or interact with beta2-microglobulin. It can activate multiple signalling pathways in primary NK cells, gamma delta T cells, and CD8+ alpha beta T cells, resulting in the production of cytokines and chemokines.ULBP1 is expressed in wide range of tissues including heart, brain, lung, liver, bone marrow and some tumour cells, T-cells, B-cells, As an unconventional member of the MHC class I family, ULBP1 is able to interact with soluble CMV glycoprotein UL16 in CMV infected cells. The interaction with UL16 blocked the interaction with the NKG2D receptor, and thus might escape the immune surveillance. Furthermore, UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface. The ULBP1 regulation may have implications for development of new therapeutic strategies against cancer cells.
VE:  1 * 50 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 92-572
Lokale Artikelnummer:: PRSI92-572
Beschreibung:   ULBP1, also known as RAET1I and NKG2DL1, is a member of the ULBP/RAET1 gene family. ULBP1 plays an important role in immune responses, especially in cancer and infectious diseases, and is well-known to bind to NKG2D together with at least ULBP 2 and 3. These proteins are distantly related to major histocompatibility class I (MHC I) molecules, possessing the alpha 1 and alpha 2 Ig-like domains, but lacking the alpha 3 domain. Unlike MHC Class I, they have no capacity to bind peptide or interact with beta2-microglobulin. It can activate multiple signallling pathways in primary NK cells, gamma delta T cells, and CD8+ alpha beta T cells, resulting in the production of cytokines and chemokines.ULBP1 is expressed in wide range of tissues including heart, brain, lung, liver, bone marrow and some tumour cells, T-cells, B-cells, As an unconventional member of the MHC class I family, ULBP1 is able to interact with soluble CMV glycoprotein UL16 in CMV infected cells. The interaction with UL16 blocked the interaction with the NKG2D receptor, and thus might escape the immune surveillance. Furthermore, UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface. The ULBP1 regulation may have implications for development of new therapeutic strategies against cancer cells.
VE:  1 * 50 µG
Artikel-Nr: (APOSOR62181-500G)

Lieferant:  APOLLO SCIENTIFIC
Hersteller-Artikelnummer:: OR62181-500G
Lokale Artikelnummer:: APOSOR62181-500G
Beschreibung:   1,2,3,6-TETRAHYDROPHTHALIMIDE 1 * 500 g
VE:  1 * 500 g
Lieferant:  Sigma-Aldrich
Beschreibung:   Coomassie Brillantblau G 250, Sigma-Aldrich®
Lieferant:  Thermo Scientific
Beschreibung:   Coomassie Brillantblau G 250, rein
Lieferant:  Serva
Beschreibung:   Coomassie Brillantblau G 250
Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 92-588
Lokale Artikelnummer:: PRSI92-588
Beschreibung:   Interleukin-15 receptor subunit alpha, also known as Il15ra, is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells. Human Il15ra shares 45% amino acid sequence homology with the mouse form of the receptor. Eight isoforms of IL-15 R alpha mRNA have been identified, resulting from alternative splicing events involving different exons.Interleukin 15 (IL-15) is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 binds to the alpha subunit of the IL15 receptor (IL-15RA) with high affinity. IL-15 also binds to the beta and gamma chains of the IL-2 receptor, but not the alpha subunit of the IL2 receptor. IL-15 is structurally and functionally related to IL-2. Both cytokines share some subunits of receptors, allowing them to compete for and negatively regulate each other's activity. The number of CD8+ memory T cells is controlled by a balance between IL-15 and IL-2. Despite their many overlapping functional properties, IL-2 and IL-15 are, in fact, quite distinct players in the immune system. IL-15 is constitutively expressed by a wide variety of cell types and tissues, including monocytes, macrophages and DCs.
VE:  1 * 50 µG
Lieferant:  LABTECH
Beschreibung:   Nachfolgend sind Lampen für viele üblicherweise benutzten HPLC-UV-Detektoren sowie einige für UV-Spektrophotometer aufgeführt. Eine große Bandbreite von Lampen für andere Verfahren, einschließlich UV/VIS Spektrophotometer, Fluoreszenz- und Atomarabsorptionsspektrometer sind auf Anfrage erhältlich. Anwender sparen im Vergleich zu den OEM-Preisen erheblich. Nichts desto trotz darf er die gleichen Lampenqualität erwarten. Alle hier beschriebenen Lampen stammen von Herstellern, die eine bestimmte Qualität zugesichert haben, und sind, wie unten beschrieben, vorgetestet und garantiert.
Lieferant:  Cayman Chemical
Beschreibung:   Coomassie Brillantblau G 250
Preis auf Anfrage
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