cis-6-Amino-cyclohex-3-enecarboxylic+acid
Artikel-Nr:
(BOSSBS-7411R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7411R-A750
Lokale Artikelnummer::
BOSSBS-7411R-A750
Beschreibung:
The MARVEL domain is a 130 amino acid motif that contains four transmembrane helices, both of which have cytoplasmic N- and C-terminal regions. MARVEL domain-containing proteins are thought to participate in tight junction regulation, the biogenesis of vesicular transport carriers and in cholesterol-rich membrane apposition events. Pantophysin, also known as SYPL1 (synaptophysin-like protein 1) or H-SP1, is a 259 amino acid multi-pass membrane protein that localises to melanosomes and vesicles, as well as to the cytoplasm, and contains one MARVEL domain. Expressed as multiple alternatively spliced isoforms, pantophysin is present in tissues throughout the body where it may play a role in vesicle trafficking and protein transport. The gene encoding pantophysin maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localised to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9394R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9394R-CY3
Lokale Artikelnummer::
BOSSBS-9394R-CY3
Beschreibung:
WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WDR40A (WD-repeat-containing protein 40A), also known as DDB1- CUL4-associated factor 12, is a 453 amino acid cytoplasmic protein that contains four WD-repeats. WDR40A is highly expressed in some cancer cell lines, lung cancer tissues and normal testis. A probable substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex, WRD40A is suggested to interact with DDB1. WDR40A is encoded by a gene mapping to human chromosome 9p13.3. Human chromosome 9 houses over 900 genes and comprises nearly 4% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12315R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12315R-FITC
Lokale Artikelnummer::
BOSSBS-12315R-FITC
Beschreibung:
GUP1 is a 504 amino acid multipass membrane protein of the endoplasmic reticulum that functions as a membrane bound O-acyltransferase. With specific expression in heart, GUP1 negatively regulates amino-terminal palmitoylation of Shh by HHAT, a protein that is required for Shh signaling. Deletion of the gene encoding GUP1 results in higher sensibility to specific sphinogolipid biosynthesis inhibitors and resistance to ergosterol biosynthesis inhibitors, indicating that GUP1 is an essential component in lipid metabolism. Also, GUP1 also seems to be important for cell wall assembly and stability due to evidence in Saccharomyces cerevisiae GUP1 mutants, which exhibit altered plasma membrane lipid composition and membrane potential.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12676R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12676R-A680
Lokale Artikelnummer::
BOSSBS-12676R-A680
Beschreibung:
Complete remission of acute promyelocytic leukaemia can be achieved by treating patients with retinoic acid, and PML-RAR-a (promyelocytic leukaemia-retinoic acid receptor alpha fusion protein) plays a major role in mediating retinoic acid effects in leukaemia cells. The retinoic acid-induced gene, PRAM-1 (PML-RAR-a target gene encoding an adaptor molecule 1) encodes an adaptor protein which is expressed and modulated during normal human myelopoiesis. PRAM-1 expression is hindered by expression of PML-RAR-a. The 718 amino acid PRAM-1 protein contains eight N-terminal proline-rich repeats and several proline residues that are clustered as type I or type II SH3 recognition motifs. PRAM-1 demonstrates expression in hematopoietic tissues and lung.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12315R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12315R-A647
Lokale Artikelnummer::
BOSSBS-12315R-A647
Beschreibung:
GUP1 is a 504 amino acid multipass membrane protein of the endoplasmic reticulum that functions as a membrane bound O-acyltransferase. With specific expression in heart, GUP1 negatively regulates amino-terminal palmitoylation of Shh by HHAT, a protein that is required for Shh signaling. Deletion of the gene encoding GUP1 results in higher sensibility to specific sphinogolipid biosynthesis inhibitors and resistance to ergosterol biosynthesis inhibitors, indicating that GUP1 is an essential component in lipid metabolism. Also, GUP1 also seems to be important for cell wall assembly and stability due to evidence in Saccharomyces cerevisiae GUP1 mutants, which exhibit altered plasma membrane lipid composition and membrane potential.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12315R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12315R-A488
Lokale Artikelnummer::
BOSSBS-12315R-A488
Beschreibung:
GUP1 is a 504 amino acid multipass membrane protein of the endoplasmic reticulum that functions as a membrane bound O-acyltransferase. With specific expression in heart, GUP1 negatively regulates amino-terminal palmitoylation of Shh by HHAT, a protein that is required for Shh signaling. Deletion of the gene encoding GUP1 results in higher sensibility to specific sphinogolipid biosynthesis inhibitors and resistance to ergosterol biosynthesis inhibitors, indicating that GUP1 is an essential component in lipid metabolism. Also, GUP1 also seems to be important for cell wall assembly and stability due to evidence in Saccharomyces cerevisiae GUP1 mutants, which exhibit altered plasma membrane lipid composition and membrane potential.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12315R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12315R-A350
Lokale Artikelnummer::
BOSSBS-12315R-A350
Beschreibung:
GUP1 is a 504 amino acid multipass membrane protein of the endoplasmic reticulum that functions as a membrane bound O-acyltransferase. With specific expression in heart, GUP1 negatively regulates amino-terminal palmitoylation of Shh by HHAT, a protein that is required for Shh signaling. Deletion of the gene encoding GUP1 results in higher sensibility to specific sphinogolipid biosynthesis inhibitors and resistance to ergosterol biosynthesis inhibitors, indicating that GUP1 is an essential component in lipid metabolism. Also, GUP1 also seems to be important for cell wall assembly and stability due to evidence in Saccharomyces cerevisiae GUP1 mutants, which exhibit altered plasma membrane lipid composition and membrane potential.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Fura-2, AM ester is a ratiometric fluorescent dye that binds to free intracellular calcium, and is the preferred dye for ratiometric imaging microscopy. Fura-2, AM ester is membrane-permeant and thus can be loaded into cells via incubation.
Artikel-Nr:
(BOSSBS-1603R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1603R-A647
Lokale Artikelnummer::
BOSSBS-1603R-A647
Beschreibung:
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1603R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1603R-A350
Lokale Artikelnummer::
BOSSBS-1603R-A350
Beschreibung:
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5813R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5813R-CY3
Lokale Artikelnummer::
BOSSBS-5813R-CY3
Beschreibung:
Proline oxidase catalyzes the conversion of proline to pyrroline-5-carboxylate, or P5C during the degradation of the amino acid Proline. Defects in PRODH are the cause of hyperprolinemia type 1, a disorder characterized by elevated serum proline levels. Defective PRODH may be involved in the psychiatric and behavioral phenotypes associated with the 22q11 velocardiofacial and DiGeorge syndrome and may be associated with susceptibility to schizophrenia 4 (SCZD4).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9616R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9616R-CY5.5
Lokale Artikelnummer::
BOSSBS-9616R-CY5.5
Beschreibung:
Ubr7 is a 425 amino acid protein that contains one UBR-type zinc finger and one PHD zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr7 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5813R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5813R-CY5.5
Lokale Artikelnummer::
BOSSBS-5813R-CY5.5
Beschreibung:
Proline oxidase catalyzes the conversion of proline to pyrroline-5-carboxylate, or P5C during the degradation of the amino acid Proline. Defects in PRODH are the cause of hyperprolinemia type 1, a disorder characterized by elevated serum proline levels. Defective PRODH may be involved in the psychiatric and behavioral phenotypes associated with the 22q11 velocardiofacial and DiGeorge syndrome and may be associated with susceptibility to schizophrenia 4 (SCZD4).
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
Solvent Blue 38 is commonly utilized in microscopy to detect demyelination in the central nervous system. It is used as a myelin-sheath stain.
Artikel-Nr:
(BOSSBS-2526R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2526R-CY3
Lokale Artikelnummer::
BOSSBS-2526R-CY3
Beschreibung:
CD160, a 27 kDa glycoprotein, was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine rich, glycosylphosphatidylinositol anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0136R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0136R-CY7
Lokale Artikelnummer::
BOSSBS-0136R-CY7
Beschreibung:
GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.
VE:
1 * 100 µl
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