trans-4-Aminotetrahydrofuran-3-ol+hydrochloride
Artikel-Nr:
(BOSSBS-5814R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5814R-A750
Lokale Artikelnummer::
BOSSBS-5814R-A750
Beschreibung:
Prominin 2 is a 112 kDa glycoporotein structurally related to Prominin 1 (CD133) although amino acid similarity is not more than 30%, but their genomic organisation is strikingly similar. Like Prominin 1, the prominin 2 exhibit similar membrane topology with 5 trans-membrane domains and two large glycosylated extracellular domains. Similar to Prominin1 localization, the Prominin 2 is also associated with membrane protrusions of the epithelial cells from adult kidney, and all along the digestive track and other epithelial tissues.Prominin 2 expression is down-regulated in aggressive prostate cancer cell lines and transient transfection of PROML2 expression vectors has been shown to induce apoptosis in cultured prostate cancer cells, suggesting a tumor suppressive role for Prominin 2. Prominin 2 expression is likely to be involved in growth suppression in the prostate, and down-regulation of Prominin 2 may disrupt normal prostatic homeostasis and lead to uncontrolled prostatic growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11241R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11241R-A750
Lokale Artikelnummer::
BOSSBS-11241R-A750
Beschreibung:
Adaptins are heterotetrameric subunits of adaptors, which are complexes involved in the formation of Clathrin-coated pits for vesicle-mediated endocytosis. Clathrin and its associated heterotetrameric protein complexes make up the main protein components of the coat surrounding the cytoplasmic face of coated vesicles. The Adaptin family, comprising a, b, and g classes, is also responsible for the transport of ligand-receptor complexes from plasma membranes and the trans-Golgi network to lysosomes. Two main types of adaptor proteins (APs), AP-1 and AP-2, are found in Clathrin-coated structures located at the Golgi complex and the plasma membrane of mammalian cells, respectively. Adaptor protein complex 2 (AP-2) is composed of two large Adaptins (a1A/AP2A1 and b1/AP2B1), a medium Adaptin (m2/AP-2m1) and a small Adaptin (s2 long/AP2S1). AP-2m1, a 435 amino acid protein, links Clathrin to receptors in coated vesicles.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9156R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9156R-CY3
Lokale Artikelnummer::
BOSSBS-9156R-CY3
Beschreibung:
SH3MD2 acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9). SH3MD2 may be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane. This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module. There are two named isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(CHMPFL13231.POR)
Lieferant:
CHEMPUR
Hersteller-Artikelnummer::
FL13231.POR
Lokale Artikelnummer::
CHMPFL13231.POR
Beschreibung:
3-Brom-5-fluorzimtsäure
VE:
1 * 1 ST
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
4-Fluorphenylhydraziniumchlorid 97%
Artikel-Nr:
(A1706.1000)
Lieferant:
PanReac AppliChem
Hersteller-Artikelnummer::
A1706.1000
Lokale Artikelnummer::
APLIA1706.1000
Beschreibung:
L(+)-Lysin Monohydrochlorid
VE:
1 * 1 kg
Artikel-Nr:
(1031569.)
Lieferant:
USP
Hersteller-Artikelnummer::
1031569
Lokale Artikelnummer::
USPH1031569
Beschreibung:
USP-Referenzstandards sind für die Durchführung offizieller USP-NF-Tests und -Analysen spezifiziert. USP stellt auch Referenzstandards bereit, die im Food Chemicals Codex spezifiziert sind, sowie authentische Substanzen – hochwertige chemische Proben – als Service für analytische, klinische, pharmazeutische und Forschungslabore. Um Genauigkeit und Reproduzierbarkeit zu bestätigen, werden USP-Referenzstandards von mehreren unabhängigen Laboren, darunter USP-, kommerzielle, behördliche und akademische Labore, streng getestet und bewertet. USP stellt auch öffentlich zugängliche, offizielle Dokumentstandards für pharmazeutische Inhaltsstoffe in der USP-NF bereit, die direkt mit unseren primären Referenzstandards verknüpft sind.
VE:
1 * 15 mg
Lieferant:
Sigma-Aldrich
Beschreibung:
2-Methylbut-3-en-2-ol, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-11242R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11242R-A647
Lokale Artikelnummer::
BOSSBS-11242R-A647
Beschreibung:
Adaptins are heterotetrameric subunits of adaptors, which are complexes involved in the formation of Clathrin-coated pits for vesicle-mediated endocytosis. Clathrin and its associated heterotetrameric protein complexes make up the main protein components of the coat surrounding the cytoplasmic face of coated vesicles. The Adaptin family, comprising a, b, and g classes, is also responsible for the transport of ligand-receptor complexes from plasma membranes and the trans-Golgi network to lysosomes. Two main types of adaptor proteins (APs), AP-1 and AP-2, are found in Clathrin-coated structures located at the Golgi complex and the plasma membrane of mammalian cells, respectively. Adaptor protein complex 2 (AP-2) is composed of two large Adaptins (a1A/AP2A1 and b1/AP2B1), a medium Adaptin (m2/AP-2m1) and a small Adaptin (s2 long/AP2S1). AP-2m1, a 435 amino acid protein, links Clathrin to receptors in coated vesicles.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5814R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5814R-HRP
Lokale Artikelnummer::
BOSSBS-5814R-HRP
Beschreibung:
Prominin 2 is a 112 kDa glycoporotein structurally related to Prominin 1 (CD133) although amino acid similarity is not more than 30%, but their genomic organization is strikingly similar. Like Prominin 1, the prominin 2 exhibit similar membrane topology with 5 trans-membrane domains and two large glycosylated extracellular domains. Similar to Prominin1 localization, the Prominin 2 is also associated with membrane protrusions of the epithelial cells from adult kidney, and all along the digestive track and other epithelial tissues.Prominin 2 expression is down-regulated in aggressive prostate cancer cell lines and transient transfection of PROML2 expression vectors has been shown to induce apoptosis in cultured prostate cancer cells, suggesting a tumor suppressive role for Prominin 2. Prominin 2 expression is likely to be involved in growth suppression in the prostate, and down-regulation of Prominin 2 may disrupt normal prostatic homeostasis and lead to uncontrolled prostatic growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11333R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11333R-A488
Lokale Artikelnummer::
BOSSBS-11333R-A488
Beschreibung:
Clathrin-coated pits and vesicles are assembled for receptor-mediated endocytosis through interaction with Clathrin associated protein complexes. Vesicle transport is mediated from the trans-Golgi network by the adapter complex AP-1 and from the plasma membrane by the AP-2 complex. The AP-1 and AP-2 adapter protein complexes consist of Clathrin binding Adaptin proteins (g and b1 for AP-1, a and b2 for AP-2) and two smaller subunits known as AP50 and AP17. The a and b Adaptin chains have a similar two-domain organization with C-terminal domains that vary in both sequence and length. a-Adaptin splice variants A and C display variable relative expression levels and differential distribution in different tissues. AP-3 (also designated AP180 or F1-20) is a synapse-specific Clathrin assembly protein. The protein CALM (Clathrin assembly protein lymphoid myeloid leukemia) is highly homologous to AP180 and may also be involved in Clathrin assembly.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11333R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11333R-A647
Lokale Artikelnummer::
BOSSBS-11333R-A647
Beschreibung:
Clathrin-coated pits and vesicles are assembled for receptor-mediated endocytosis through interaction with Clathrin associated protein complexes. Vesicle transport is mediated from the trans-Golgi network by the adapter complex AP-1 and from the plasma membrane by the AP-2 complex. The AP-1 and AP-2 adapter protein complexes consist of Clathrin binding Adaptin proteins (g and b1 for AP-1, a and b2 for AP-2) and two smaller subunits known as AP50 and AP17. The a and b Adaptin chains have a similar two-domain organization with C-terminal domains that vary in both sequence and length. a-Adaptin splice variants A and C display variable relative expression levels and differential distribution in different tissues. AP-3 (also designated AP180 or F1-20) is a synapse-specific Clathrin assembly protein. The protein CALM (Clathrin assembly protein lymphoid myeloid leukemia) is highly homologous to AP180 and may also be involved in Clathrin assembly.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11333R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11333R-FITC
Lokale Artikelnummer::
BOSSBS-11333R-FITC
Beschreibung:
Clathrin-coated pits and vesicles are assembled for receptor-mediated endocytosis through interaction with Clathrin associated protein complexes. Vesicle transport is mediated from the trans-Golgi network by the adapter complex AP-1 and from the plasma membrane by the AP-2 complex. The AP-1 and AP-2 adapter protein complexes consist of Clathrin binding Adaptin proteins (g and b1 for AP-1, a and b2 for AP-2) and two smaller subunits known as AP50 and AP17. The a and b Adaptin chains have a similar two-domain organization with C-terminal domains that vary in both sequence and length. a-Adaptin splice variants A and C display variable relative expression levels and differential distribution in different tissues. AP-3 (also designated AP180 or F1-20) is a synapse-specific Clathrin assembly protein. The protein CALM (Clathrin assembly protein lymphoid myeloid leukemia) is highly homologous to AP180 and may also be involved in Clathrin assembly.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11333R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11333R-A350
Lokale Artikelnummer::
BOSSBS-11333R-A350
Beschreibung:
Clathrin-coated pits and vesicles are assembled for receptor-mediated endocytosis through interaction with Clathrin associated protein complexes. Vesicle transport is mediated from the trans-Golgi network by the adapter complex AP-1 and from the plasma membrane by the AP-2 complex. The AP-1 and AP-2 adapter protein complexes consist of Clathrin binding Adaptin proteins (g and b1 for AP-1, a and b2 for AP-2) and two smaller subunits known as AP50 and AP17. The a and b Adaptin chains have a similar two-domain organization with C-terminal domains that vary in both sequence and length. a-Adaptin splice variants A and C display variable relative expression levels and differential distribution in different tissues. AP-3 (also designated AP180 or F1-20) is a synapse-specific Clathrin assembly protein. The protein CALM (Clathrin assembly protein lymphoid myeloid leukemia) is highly homologous to AP180 and may also be involved in Clathrin assembly.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11333R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11333R-A555
Lokale Artikelnummer::
BOSSBS-11333R-A555
Beschreibung:
Clathrin-coated pits and vesicles are assembled for receptor-mediated endocytosis through interaction with Clathrin associated protein complexes. Vesicle transport is mediated from the trans-Golgi network by the adapter complex AP-1 and from the plasma membrane by the AP-2 complex. The AP-1 and AP-2 adapter protein complexes consist of Clathrin binding Adaptin proteins (g and b1 for AP-1, a and b2 for AP-2) and two smaller subunits known as AP50 and AP17. The a and b Adaptin chains have a similar two-domain organization with C-terminal domains that vary in both sequence and length. a-Adaptin splice variants A and C display variable relative expression levels and differential distribution in different tissues. AP-3 (also designated AP180 or F1-20) is a synapse-specific Clathrin assembly protein. The protein CALM (Clathrin assembly protein lymphoid myeloid leukemia) is highly homologous to AP180 and may also be involved in Clathrin assembly.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
2-Bromphenylhydraziniumchlorid 95%
Preis auf Anfrage
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