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BIOSS INC
Artikel-Nr:
(BOSSBS-5965R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5965R-A647
Lokale Artikelnummer::
BOSSBS-5965R-A647
Beschreibung:
The protein encoded by this gene belongs to the ETS family of transcription factors, which is a large group of evolutionarily conserved transcriptional regulators that play an important role in a variety of cellular processes throughout development and differentiation, and are involved in oncogenesis as well. This protein is predominantly expressed in hematopoietic tissues. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene (PMID:11108721).[provided by RefSeq, May 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5347R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5347R-A350
Lokale Artikelnummer::
BOSSBS-5347R-A350
Beschreibung:
The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq].eIF4G1 (eukaryotic translation Initiation Factor 4 Gamma 1) is a component of the protein complex eIF-4 which is involved in the recognition of the mRNA cap ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of mRNA to the ribosome. eIF4G plays a critical role in protein expression and is at the center of a complex regulatory network. Together with the cap-binding protein eIF4E, it recruits the small ribosomal subunit to the 5'-end of mRNA and promotes the assembly of a functional translation initiation complex which scans along the mRNA to the translation start codon. Human eIF4G contains three consecutive HEAT domains, as well as long unstructured regions involved in multiple protein-protein interactions. The interactions of eIF4G1 with other factors are largely unknown.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2420R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2420R-FITC
Lokale Artikelnummer::
BOSSBS-2420R-FITC
Beschreibung:
Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11648R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11648R
Lokale Artikelnummer::
BOSSBS-11648R
Beschreibung:
BSMAP is a 342 amino acid type-I membrane glycoprotein that localizes to organelle membranes and belongs to the TMEM59 family. Expressed at high levels in brain tissue, BSMAP is thought to play a role in brain function and central nervous system activity. The gene encoding BSMAP maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11721R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11721R
Lokale Artikelnummer::
BOSSBS-11721R
Beschreibung:
Transcriptional repressor which may play a role in development of the central nervous system (CNS).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0539R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0539R-A350
Lokale Artikelnummer::
BOSSBS-0539R-A350
Beschreibung:
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10409R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10409R
Lokale Artikelnummer::
BOSSBS-10409R
Beschreibung:
Eotaxin 3 is a recently discovered CC chemokine. It binds to the CCR3 receptor and is highly chemotactic for eosinophils and basophils.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8317R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8317R
Lokale Artikelnummer::
BOSSBS-8317R
Beschreibung:
HDHD2 (haloacid dehalogenase-like hydrolase domain containing 2) is also known as DKFZp564D1378 and is a 259 amino acid protein that is expressed as two isoforms produced by alternative splicing. HDHD2 belongs to the HAD-like hydrolase superfamily, which contains a group of hydrolase enzymes that differ from the å/∫
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1302R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1302R-CY5
Lokale Artikelnummer::
BOSSBS-1302R-CY5
Beschreibung:
Glutamic Acid Decarboxylase (GAD) catalyzes the conversion of L glutamate to g-aminobutyric acid (GABA), the principal inhibitory neurotransmitter in the brain, and a putative paracrine signal molecule in pancreatic islets. GAD has a restricted tissue distribution. It is highly expressed in the cytoplasm of GABAergic neurons in the central nervous system (CNS) and pancreatic beta cells. It is also present in other non-neuronal tissues such as testis, oviduct and ovary. GAD is also transiently expressed in non-GABAergic cells of the embryonic and adult nervous system, suggesting its involvement in development and plasticity. GAD exists as two isoforms, GAD65 and GAD67 (molecular masses of 65 and 67 kD, respectively) that are encoded by two different genes. GAD65 is an ampiphilic, membraneanchored protein, (585 amino acid residues) and is encoded on human chromosome 10. GAD67 is a cytoplasmic protein (594 amino acid residues) and is encoded on chromosome 2. There is 64% amino acid identity between the two isoforms, with the highest diversity located at the N terminus, which in GAD65 is required for targeting the enzyme to GABA-containing secretory vesicles. The two isoforms appear to have distinct intraneuronal distribution in the brain. GAD65 has been identified as an autoantigen in insulindependent diabetes mellitus (IDDM) and stiff-man syndrome (SMS), IDDM is an autoimmune disease that results from T cell mediated destruction of pancreatic insulin-secreting beta cells. Islet-reactive T cells and primarily to GAD65 (also named beta cell autoantigen) can be detected in peripheral blood of 80% of recent-onset IDD patients and in pre-diabetic high-risk subjects before onset of clinical symptoms. This suggests that GAD may be an important marker in the early stages of the disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1268R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1268R-CY7
Lokale Artikelnummer::
BOSSBS-1268R-CY7
Beschreibung:
Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5415R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5415R-HRP
Lokale Artikelnummer::
BOSSBS-5415R-HRP
Beschreibung:
Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7762R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7762R-CY7
Lokale Artikelnummer::
BOSSBS-7762R-CY7
Beschreibung:
Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3058R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3058R-A555
Lokale Artikelnummer::
BOSSBS-3058R-A555
Beschreibung:
Induces apoptosis and anoikis. The isoforms vary in cytotoxicity with isoform BimS being the most potent and isoform BimEL being the least potent.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3101R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3101R-A555
Lokale Artikelnummer::
BOSSBS-3101R-A555
Beschreibung:
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4642R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4642R-CY5
Lokale Artikelnummer::
BOSSBS-4642R-CY5
Beschreibung:
Kilham Rat Virus/KRV-VP1/KRV-VP2 (C-terminus)
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4643R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4643R-HRP
Lokale Artikelnummer::
BOSSBS-4643R-HRP
Beschreibung:
Kilham Rat Virus/KRV-VP1/KRV-VP2 (C-terminus)
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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