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BIOSS INC
Artikel-Nr:
(BOSSBS-1767R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1767R-A488
Lokale Artikelnummer::
BOSSBS-1767R-A488
Beschreibung:
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Fibroblast growth factor 13 (FGF13) is probably involved in nervous system development and function. Alternative splicing of this gene results in several transcript variants encoding different isoforms with different N-termini.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11759R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11759R-FITC
Lokale Artikelnummer::
BOSSBS-11759R-FITC
Beschreibung:
Atlastins are Golgi-localized, integral membrane proteins that function as GTPases. The Atlastin proteins, also designated SPG3A and guanylate-binding protein 3, comprise a Dynamin superfamily that plays a role in axonal maintenance. Hereditary spastic paraplegia (HSP) is an inherited neurodegenerative disorder that is characterized by retrograde axonal degeneration. HSP primarily affects long corticospinal neurons and causes spastic lower extremity weakness. Spastin, a microtubule (MT)-severing AAA ATPase, is a binding partner of Atlastin that is involved in membrane dynamics. This Spastin/Atlastin binding may be involved in the biochemical pathway that leads to HSP development. Mutations in the Atlastin gene (SPG3A) account for approximately 10% of all autosomal dominant HSPs, while mutations in the Spastin gene (SPG4) account for almost 40%.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3187R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3187R-A555
Lokale Artikelnummer::
BOSSBS-3187R-A555
Beschreibung:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3785R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3785R-A555
Lokale Artikelnummer::
BOSSBS-3785R-A555
Beschreibung:
Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase related apoptosis inducing protein kinases). DRAKs contain an N terminal kinase domain and a C terminal regulation domain. Overexpression of DRAK2 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7945R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7945R-HRP
Lokale Artikelnummer::
BOSSBS-7945R-HRP
Beschreibung:
ABHD14B has hydrolase activity towards p-nitrophenyl butyrate (in vitro). It may activate transcription. There are 2 isoforms produced by alternative splicing.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0442R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0442R-CY5.5
Lokale Artikelnummer::
BOSSBS-0442R-CY5.5
Beschreibung:
ACTH stimulates the adrenal glands to release cortisol. MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes. Beta-endorphin and Met-enkephalin are endogenous opiates.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4075R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4075R-A555
Lokale Artikelnummer::
BOSSBS-4075R-A555
Beschreibung:
Dystroglycan is a laminin binding component of the dystrophin-glycoprotein complex which provides a linkage between the subsarcolemmal cytoskeleton and the extracellular matrix. Dystroglycan 1 is a candidate gene for the site of the mutation in autosomal recessive muscular dystrophies. The dramatic reduction of dystroglycan 1 in Duchenne muscular dystrophy leads to a loss of linkage between the sarcolemma and extracellular matrix, rendering muscle fibers more susceptible to necrosis. Dystroglycan also functions as dual receptor for agrin and laminin-2 in the Schwann cell membrane. The muscle and nonmuscle isoforms of dystroglycan differ by carbohydrate moieties but not protein sequence. Alternative splicing results in multiple transcript variants all encoding the same protein.[provided by RefSeq, Apr 2010]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5182R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5182R-FITC
Lokale Artikelnummer::
BOSSBS-5182R-FITC
Beschreibung:
AKT, also known as protein kinase B (PKB), is a 57 kDa serine/threonine protein kinase. There are three mammalian isoforms of Akt: AKT1 (PKB alpha), AKT2 (PKB beta) and AKT3 (PKB gamma) with AKT2 and AKT3 being approximately 82% identical with the AKT1 isoform. Each isoform has a pleckstrin homology (PH)domain, a kinase domain and a carboxy terminal regulatory domain. AKT was originally cloned from the retrovirus AKT8, and is a key regulator of many signal transduction pathways. Its tight control over cell proliferation and cell viability are manifold; overexpression or inappropriate activation of AKT has been seen in many types of cancer. AKT mediates many of the downstream events of phosphatidylinositol 3 kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI3 kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1914R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1914R-CY3
Lokale Artikelnummer::
BOSSBS-1914R-CY3
Beschreibung:
Thrombin is the final protease in the blood coagulation cascade and serves both pro- and anticoagulant functions through the cleavage of several targets. The ability of thrombin to specifically recognize a wide range of substrates derives from interactions which occur outside of the active site of thrombin. Thrombin possesses two anion binding exosites which mediate many of its interactions with cofactors and substrates, and although many structures of thrombin have been solved, few such interactions have been described in molecular detail. Glycosaminoglycan binding to exosite II of thrombin plays a major role in switching off the procoagulant functions of thrombin by mediating its irreversible inhibition by circulating serpins and by its binding to the endothelial cell surface receptor thrombomodulin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1770R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1770R-A350
Lokale Artikelnummer::
BOSSBS-1770R-A350
Beschreibung:
ATP-dependent microtubule severing protein. Microtubule severing may promote reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Golgi and for completion of the abscission stage of cytokinesis. May also play a role in axon growth and the formation of axonal branches.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13480R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13480R
Lokale Artikelnummer::
BOSSBS-13480R
Beschreibung:
Anti-GOLGA3 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6164R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6164R-A488
Lokale Artikelnummer::
BOSSBS-6164R-A488
Beschreibung:
Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5497R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5497R-A350
Lokale Artikelnummer::
BOSSBS-5497R-A350
Beschreibung:
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15289R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15289R-A488
Lokale Artikelnummer::
BOSSBS-15289R-A488
Beschreibung:
C8orf4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15480R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15480R-HRP
Lokale Artikelnummer::
BOSSBS-15480R-HRP
Beschreibung:
Hho1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11051R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11051R-A750
Lokale Artikelnummer::
BOSSBS-11051R-A750
Beschreibung:
HAPLN2 is a 340 amino acid protein encoded by the human gene HAPLN2. HAPLN2 belongs to the HAPLN family and contains one immunoglobulin (Ig)-like, V-type domain and two link domains. HAPLN2 mediates a firm binding of versican V2 to hyaluronic acid. HAPLN2 is believed to play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS), which facilitates neuronal conduction and general structural stabilisation. HAPLN2 may also be involved in the formation of extracellular matrices, contributing to perineuronal nets and facilitating the understanding of a functional role of these extracellular matrices. HAPLN2 is found in several nuclei throughout the midbrain and hindbrain in a perineuronal net pattern.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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