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BIOSS INC
Artikel-Nr:
(BOSSBS-4726R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4726R-A555
Lokale Artikelnummer::
BOSSBS-4726R-A555
Beschreibung:
Gross cystic disease is a common premenopausal disorder in which gross cysts are the predominant pathologic lesion. It is characterized by production of a fluid secretion which accumulates in the breast cysts. Gross cystic disease fluid is a pathologic secretion from breast composed of several glycoproteins, including a unique 15 kDa monomer protein, GCDFP 15. The cells within the body that produce GCDFP 15 appear to be restricted primarily to those with apocrine function. Studies have found GCDFP 15 to be a highly specific and sensitive marker for breast cancer.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4984R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4984R-HRP
Lokale Artikelnummer::
BOSSBS-4984R-HRP
Beschreibung:
p130 is related both in structure and function to the retinoblastoma tumor suppressor protein and p107 (collectively known as pocket proteins) and is known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S phase of the cell cycle. Binding of p130 converts E2F transcription factors from transcriptional activators to transcriptional repressors.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5049R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5049R-A647
Lokale Artikelnummer::
BOSSBS-5049R-A647
Beschreibung:
Catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3-25-hydroxylase activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5051R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5051R-A647
Lokale Artikelnummer::
BOSSBS-5051R-A647
Beschreibung:
The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed exclusively in the brain, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, producing a product that is more soluble than cholesterol and able to be exported from the brain.Cyp46 is also known as 24S-cholesterol hydroxylase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5349R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5349R-A350
Lokale Artikelnummer::
BOSSBS-5349R-A350
Beschreibung:
PLM (FXYD1)is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. PLM may be phosphorylated by several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5511R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5511R-CY7
Lokale Artikelnummer::
BOSSBS-5511R-CY7
Beschreibung:
This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0782R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0782R
Lokale Artikelnummer::
BOSSBS-0782R
Beschreibung:
Anti-IL6 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2483R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2483R
Lokale Artikelnummer::
BOSSBS-2483R
Beschreibung:
Anti-CCL24 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7886R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7886R
Lokale Artikelnummer::
BOSSBS-7886R
Beschreibung:
May play a role in transcriptional regulation. Component of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor b (P-TEFb).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13519R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13519R
Lokale Artikelnummer::
BOSSBS-13519R
Beschreibung:
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR146 (G protein-coupled receptor 146), also known as PGR8, is a 333 amino acid multi-pass transmembrane protein that belongs to the G-protein coupled receptor 1 family. Characterized as an orphan receptor for which its endogenous ligand has yet to be identified, GPR146 is thought to play a role in signaling events throughout the cell.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1562R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1562R-CY3
Lokale Artikelnummer::
BOSSBS-1562R-CY3
Beschreibung:
Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0549R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0549R-CY5.5
Lokale Artikelnummer::
BOSSBS-0549R-CY5.5
Beschreibung:
Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of GPR56 in the developing brain and binding to GPR56 inhibits neuronal migration and activates the RhoA pathway by coupling GPR56 to GNA13 and possibly GNA12.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3730R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3730R-CY3
Lokale Artikelnummer::
BOSSBS-3730R-CY3
Beschreibung:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. There have been at least 12 different PKC isoforms identified in humans to date including alpha, beta I, beta II, gamma, delta, epsilon, zeta, eta, theta, iota, lambda, and mu. PKC gamma is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2075R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2075R-A488
Lokale Artikelnummer::
BOSSBS-2075R-A488
Beschreibung:
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2495R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2495R-CY7
Lokale Artikelnummer::
BOSSBS-2495R-CY7
Beschreibung:
Receptor for TNFSF8/CD3L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12259R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12259R-CY7
Lokale Artikelnummer::
BOSSBS-12259R-CY7
Beschreibung:
Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which are essential interfaces for biological recognition processes. Fucosyltransferases (FucTs) catalyze the covalent association of fucose to different positional linkages on sugar acceptor molecules. The carbohydrate moieties that are generated are covalently attached to cell surfaces and are necessary to ensure a surface contour that satisfies a variety of physiological roles. FucT-XI is a 492 amino acid single-pass type II membrane protein that belongs to the glycosyltransferase 10 family. Localizing to Golgi apparatus, FucT-XI may act as a fucosyltransferase and exists as two alternatively spliced isoforms. The gene encoding FucT-XI maps to mouse chromosome 14 A3.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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