Supplier >
BIOSENSIS PTY
Drucken
Sie suchten nach:
410 results were found
BIOSENSIS PTY
Artikel-Nr:
(BSENR-1682-500)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-1682-500
Lokale Artikelnummer::
BSENR-1682-500
Beschreibung:
Autosomal recessive mutations in DJ-1 cause early-onset familial Parkinson's disease. DJ-1 is considered a redox-sensitive cytoplasmic protein found in brain as well as other cell types.
VE:
1 * 500 µG
Artikel-Nr:
(BSENR-1549-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-1549-100
Lokale Artikelnummer::
BSENR-1549-100
Beschreibung:
Histone H3 is a core component of nucleosome.
VE:
1 * 100 µl
Artikel-Nr:
(BSENR-1681-500)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-1681-500
Lokale Artikelnummer::
BSENR-1681-500
Beschreibung:
Autosomal dominant mutations in presenilin 2 are the second major cause of early-onset familial Alzheimer's disease. Presenilin 2 is a multi-transmembrane protein which undergoes endoprotelysis to form an N-terminal fragment of about 29 kDa and C-terminal fragment of about 22 kDa. Presenilin 2 forms the catalytic core of the gamma-secretase complex which cleaves type 1 transmembrane proteins including the amyloid precursor protein to generate the C-terminus of the amyloid beta peptide.
VE:
1 * 500 µG
Artikel-Nr:
(BSENM-1646-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
M-1646-100
Lokale Artikelnummer::
BSENM-1646-100
Beschreibung:
Anti-ACTA Mouse T4 Antibody [clone: 5J11]
VE:
1 * 100 µG
Artikel-Nr:
(BSENS-044-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
S-044-100
Lokale Artikelnummer::
BSENS-044-100
Beschreibung:
NULL
VE:
1 * 100 µG
Artikel-Nr:
(BSENR-1381-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-1381-100
Lokale Artikelnummer::
BSENR-1381-100
Beschreibung:
Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14. PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels. MMP2 isoform 2 mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, NFAT and IRF transcriptional pathways. Catalytic activity of MMP2 causes cleavage of gelatin type I and collagen types IV, V, VII, X. Cleaves the collagen-like sequence Pro-Gln-Gly-|-Ile-Ala-Gly-Gln. (Ref: uniprot.org).
VE:
1 * 100 µG
Lieferant:
Biosensis
Beschreibung:
The Biosensis Mature BDNF Rapid™ enzyme-linked immunosorbent assay (ELISA) kit is a sandwich ELISA that allows the quantification of BDNF in less than 3 hours in cell culture supernatants, serum, plasma (citrate and EDTA), cell lysates, human milk and brain extracts only if used as directed, with a simplified protocol and no loss of sensitivity or specificity.
Artikel-Nr:
(BSENTR-150-FJB)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
TR-150-FJB
Lokale Artikelnummer::
BSENTR-150-FJB
Beschreibung:
The causes and effects of neuronal degeneration are of major interest to a wide variety of neuroscientists. Paralleling this growing interest is an increasing number of methods applicable to the detection of neuronal degeneration. The fluorescent dye Fluoro-Jade® B (FJB), like its more purified brother Fluoro-Jade® C (FJC), is an anionic fluorescein derivative useful for the histological staining of neurons undergoing degeneration.
VE:
1 * 30 mg
Lieferant:
Biosensis
Beschreibung:
The Biosensis proBDNF Rapid™ enzyme-linked immunosorbent assay (ELISA) kit is a sandwich ELISA that allows the specific, fast and reliable quantification of proBDNF in less than 4 hours in cell culture supernatants, cell lysates, serum, citrate-plasma and tissue extracts only if used as directed.
Artikel-Nr:
(BSENR-184-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-184-100
Lokale Artikelnummer::
BSENR-184-100
Beschreibung:
FUNCTION: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. SUBCELLULAR LOCATION: Cytoplasm; cytosol. Cell membrane. Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components. ALTERNATIVE PRODUCTS: 8 named isoforms produced by alternative splicing. Additional isoforms seem to exist. Isoforms differ from each other by the presence or absence of up to 5 of the 15 exons. One of these optional exons contains the additional tau/MAP repeat. TISSUE SPECIFICITY: Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system. DEVELOPMENTAL STAGE: Four-repeat (type II) tau is expressed in an adult-specific manner and is not found in fetal brain, whereas three-repeat (type I) tau is found in both adult and fetal brain. DOMAIN: The tau/MAP repeat binds to tubulin. In Alzheimer disease, the neuronal cytoskeleton in the brain is progressively disrupted and replaced by tangles of paired helical filaments and straight filaments, mainly composed of hyperphosphorylated forms of Microtubule-associated protein Tau. Defects in Microtubule-associated protein Tau are a cause of frontotemporal dementia and parkinsonism linked to chromosome 17, as well as a number of other neurodegenerative diseases.
VE:
1 * 100 µl
Artikel-Nr:
(BSENS-054-500)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
S-054-500
Lokale Artikelnummer::
BSENS-054-500
Beschreibung:
NT3 is a member of the neurotrophin family, that controls survival and differentiation of visceral and proprioceptive sensory neurons. NT3 is closely related to both NGF and BDNF. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NT3-deficient mice generated by gene targeting display sevvere movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. SUBCELLULAR LOCATION: Secreted protein. TISSUE SPECIFICITY: Brain and peripheral tissues. SIMILARITY: Belongs to the NGF-beta family.
VE:
1 * 500 µG
Artikel-Nr:
(BSENS-064-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
S-064-100
Lokale Artikelnummer::
BSENS-064-100
Beschreibung:
SUMO-1 binds to a wide range of target proteins as part of a post-translational modification system. Unlike ubiquitin, it does not seem to target protein for degradation, but is involved in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis, apoptosis, protein stability and signal transduction. SUBUNIT: Covalently attached to a number of proteins such as PML, RANGAP1, HIPK2, SP100, p53, p73alpha, MDM2, JUN and DNMT3B. Also interacts with HIF1A, HIPK2, HIPK3, CHD3, PIAS1, EXOSC9, TDG, RAD51 and RAD52. SUBCELLULAR LOCATION: Nucleus; nuclear membrane. Nucleus; nucleoplasm; nuclear speckle. Cytoplasm. SIMILARITY: Belongs to the ubiquitin family. SMT3 subfamily. SIMILARITY: Contains 1 ubiquitin-like domain. PTM: Cleavage of the last four amino acids of the carboxy-terminus of the precursor form by SENP1 or SENP2 is necessary for function. Several pseudogenes have been reported as well as a number of alternatively spliced isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BSENR-108-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-108-100
Lokale Artikelnummer::
BSENR-108-100
Beschreibung:
DBH is an oxireductase belonging to the copper type II ascorbate-dependent monooxygenase family. DBH exists as a homotetramer composed of two non-covalently bound disulfide-linked dimers. It is present in the synaptic vesicles of postganglionic sympathetic neurons and converts dopamine to norepinephrine. It binds 2 copper ions and 1 PQQ per subunit . Depending on the presence of a signal peptide, DBH can exist in both soluble and membrane-bound forms.
VE:
1 * 100 µl
Artikel-Nr:
(BSENR-1492-50)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-1492-50
Lokale Artikelnummer::
BSENR-1492-50
Beschreibung:
Human beta-endorphin is a 31 amino acid peptide cleaved from the precursor pro-opiomelanocortin (POMC). It is an endogenous opioid peptide neurotransmitter that interacts with opioid receptors.
VE:
1 * 50 µG
Artikel-Nr:
(BSENM-1317-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
M-1317-100
Lokale Artikelnummer::
BSENM-1317-100
Beschreibung:
The V5 epitope corresponds to a region from Simian Virus Type 5 (SV5).
VE:
1 * 100 µG
Artikel-Nr:
(BSENM-377-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
M-377-100
Lokale Artikelnummer::
BSENM-377-100
Beschreibung:
Fox3 is one of a family of mammalian homologues of Fox-1. The Fox proteins are about 46kDa in size, and each includes a central highly conserved RRM type RNA recognition motif. Much interest has focused on Fox3 as a result of the recent finding that this protein corresponds to NeuN, a neuronal nuclear antigen. NeuN/Fox-3 has a function in RNA splicing and is expressed heavily and specifically in neuronal nuclei and cytoplasm. Our antibody was raised against the N-terminal 100 amino acids of human Fox3 as expressed in and purified from E. coli. We did not use full length Fox3 as immunogen since the three mammalian Fox homologues, namely Fox1, Fox2 and Fox3, include virtually identical RRM motifs. The N-terminal region of the three molecules are much more variable in the three molecules so antibodies specific for each of the three molecules can therefore be generated.
VE:
1 * 100 µl
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||
Listenansicht
