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BIOSENSIS PTY
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BIOSENSIS PTY
Artikel-Nr:
(BSENR-112-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-112-100
Lokale Artikelnummer::
BSENR-112-100
Beschreibung:
FUNCTION: Required for autophagy. SUBUNIT: Conjugated to ATG5. SUBCELLULAR LOCATION: Cytoplasm. ALTERNATIVE PRODUCTS: 2 named isoforms produced by alternative splicing. TISSUE SPECIFICITY: Ubiquitous. SIMILARITY: Belongs to the ATG12 family.
VE:
1 * 100 µl
Artikel-Nr:
(BSENR-1313-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-1313-100
Lokale Artikelnummer::
BSENR-1313-100
Beschreibung:
Maltose binding protein (MBP) is encoded by the malE gene of E.coli. MBP is often used in protein expression studies because it creates a stable fusion product that does not appear to interfere with the bioactivity of the protein of interest. It also allows for its easy purification from bacterial extracts under mild conditions.
VE:
1 * 100 µG
Artikel-Nr:
(BSENR-1621-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-1621-100
Lokale Artikelnummer::
BSENR-1621-100
Beschreibung:
This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010]
VE:
1 * 100 µG
Artikel-Nr:
(BSENC-1801-50)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
C-1801-50
Lokale Artikelnummer::
BSENC-1801-50
Beschreibung:
Calretinin is a calcium-binding protein which is abundant in auditory neurons. Ref: uniprot.org. Antibody is specific for calretinin and does not recognize closely related proteins parvalbumin and calbindin as determined by Western Blotting.
VE:
1 * 50 µl
Artikel-Nr:
(BSENC-1812-50)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
C-1812-50
Lokale Artikelnummer::
BSENC-1812-50
Beschreibung:
Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells (By similarity). Ref: uniprot.org
VE:
1 * 50 µl
Lieferant:
Biosensis
Beschreibung:
Mouse NGF (2.5S) was isolated from mouse submaxillary glands by method of Mobley et al (1976) and is a form of beta-NGF that has identical biological properties. NGF is known to regulate the survival and development of certain sympathetic and sensory neurons. It is a dimer with 2 identical polypeptide chains and dimeric molecular weight of approximately 26,500 Da. Isolation and purification of NGF from mouse submaxillary glands yields preparations of NGF (2.5S) with identical biological activity but with cleavages at the amino terminus (with the loss of 8 amino acids) and/or at the carboxy-terminus (with the loss of arginine). These preparations are named 2.5 NGF.
Artikel-Nr:
(BSENM-1818-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
M-1818-100
Lokale Artikelnummer::
BSENM-1818-100
Beschreibung:
NGF receptor antibody clone 8J2 was developed specifically as a replacement for clone MLR2, which is no longer available anywhere for commercial use. Antibody reactivity for clone 8J2 has been validated for human, mouse and rat extracellular domain of p75NTR. Clone 8J2 has been demonstrated to perform equivalent to or better than MLR2 antibody in all testing.
VE:
1 * 100 µG
Artikel-Nr:
(BSENS-1754-500)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
S-1754-500
Lokale Artikelnummer::
BSENS-1754-500
Beschreibung:
Sheep serum from non-immunised animals was purified by protein G affinity chromatography. This sheep IgG fraction can be used as negative control antibody for various immunological techniques where sheep primary antibodies are used.
VE:
1 * 500 µG
Artikel-Nr:
(BSENM-1573-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
M-1573-100
Lokale Artikelnummer::
BSENM-1573-100
Beschreibung:
Protein DJ-1 has many roles including protecting cells against oxidative stress and cell death (Ref: SwissProt). Mutations in the DJ-1 gene have been associated with rare forms of autosomal recessive early-onset Parkinson's disease.
VE:
1 * 100 µG
Artikel-Nr:
(BSENR-1803-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-1803-100
Lokale Artikelnummer::
BSENR-1803-100
Beschreibung:
May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin. Ref: uniprot.org
VE:
1 * 100 µG
Artikel-Nr:
(BSENR-107-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-107-100
Lokale Artikelnummer::
BSENR-107-100
Beschreibung:
Myelin is a membrane characteristic of the nervous tissue and functions as an insulator to increase the velocity of the stimuli being transmitted between a nerve cell body and its target. Myelin isolated from human and bovine nervous tissue is composed of approximately 80% lipid and 20% protein, and 30% of the protein fraction constitutes myelin basic protein (MBP). MBP is an 'intrinsically unstructured' protein with a high proportion (approximately 75%) of random coil, but postulated to have core elements of beta-sheet and alpha-helix. MBP is a major protein in CNS myelin and is expressed specifically in the nervous system. A detailed immunochemical examination of monoclonal and polyclonal antibody responses to MBP and its peptides has revealed the existence of as many as 27 antigenic determinants, many of them conformational. Topological mapping of the potential antigenic determinants onto a model of MBP secondary structure places these determinants within 11 separate regions of the molecule, including those portions that have been found to be encephalitogenic. The message for myelin basic protein is selectively translocated to the ends of the cell processes. Immunization with myelin-associated antigens including MBP significantly promotes recovery after spinal cord contusion injury in the rat model. FUNCTION: Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity). SUBUNIT: Homodimer (By similarity). SUBCELLULAR LOCATION: Myelin membrane; peripheral membrane protein; cytoplasmic side. Cytoplasmic side of myelin. TISSUE SPECIFICITY: Found in both the central and the peripheral nervous system.
VE:
1 * 100 µl
Artikel-Nr:
(BSENR-959-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-959-100
Lokale Artikelnummer::
BSENR-959-100
Beschreibung:
The beta Amyloid peptide is derived from the cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. Beta amyloid peptides are the major constituents of the plaques and tangles that occur in Alzheimer's disease.
VE:
1 * 100 µl
Artikel-Nr:
(BSENR-053-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-053-100
Lokale Artikelnummer::
BSENR-053-100
Beschreibung:
TISSUE SPECIFICITY: Predominantly expressed in trigeminal and dorsal root sensory ganglia. Isoform 1 and isoform 3 are also expressed in brain and peripheral blood mononuclear cells.
VE:
1 * 100 µl
Artikel-Nr:
(BSENR-111-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-111-100
Lokale Artikelnummer::
BSENR-111-100
Beschreibung:
FUNCTION: Required for autophagy. Conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. FUNCTION: May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. SUBCELLULAR LOCATION: Cytoplasm. Colocalizes with nonmuscle actin. ALTERNATIVE PRODUCTS: 2 named isoforms produced by alternative splicing. TISSUE SPECIFICITY: Ubiquitous. The mRNA is present at similar levels in viable and apoptotic cells, whereas the protein is dramatically highly expressed in apoptotic cells. INDUCTION: By apoptotic stimuli. PTM: Conjugated to ATG12; which is essential for autophagy, but is not required for association with isolation membrane. SIMILARITY: Belongs to the ATG5 family.
VE:
1 * 100 µl
Artikel-Nr:
(BSENM-1376-250)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
M-1376-250
Lokale Artikelnummer::
BSENM-1376-250
Beschreibung:
Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH) is a metabolic enzyme responsible for catalyzing one step in the glycolytic pathway, the reversible oxidative phosphorylation of glyceraldehyde 3-phosphate. GAPDH may have other roles in the activation of transcription and in the regulation of apoptosis as well as Alzheimer's disease and Huntington's disease. The immunogen used to raise this particular antibody was extensively purified pig GAPDH. This antibody can be used as a loading control for western blotting experiments, allowing comparison between the level of this protein and others in a cell or tissue.
VE:
1 * 250 µl
Artikel-Nr:
(BSENR-1808-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-1808-100
Lokale Artikelnummer::
BSENR-1808-100
Beschreibung:
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organisation of cells into tissues during embryonic development by interacting with other extracellular matrix components. Ref: uniprot.org. This antibody recognizes laminin isotypes alpha-1 (440 kDa), beta-1 (220 kDa) and gamma-1 (220 kDa). It also binds laminin binding protein at 120 kDa which always co-expresses with laminin.
VE:
1 * 100 µG
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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