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28 361 results were found
PROSCI
Artikel-Nr:
(PRSI27-808)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-808
Lokale Artikelnummer::
PRSI27-808
Beschreibung:
DMRTA2 is involved in gonadal differentiation. The gene is part of five novel human DM genes that map to three well-defined regions of chromosomes 1, 9, and 19 (one gene on chromosome 19 having an additional homolog on chromosome X).
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-273)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-273
Lokale Artikelnummer::
PRSI90-273
Beschreibung:
APRIL is a cytokine that belongs to the TNF superfamily and binds to TACI and BCMA. It is implicated in the regulation of tumour cell growth, is involved in monocyte/macrophage-mediated immunological processes and functions as an important survival factor for plasma blasts and bone marrow plasma cells. MultimericAPRIL™ is a high activity construct in which two trimeric APRIL ligands are artificially linked via the collagen domain of ACRP30. This construct very effectively stimulates proliferation B cell. A basic amino acid sequence (QKQKKQ) close to the N-terminus of APRIL is required for binding to negatively charged sulphated glycosaminoglycan side chains of proteoglycans. Proteoglycans mediate binding of APRIL to tumour cells as well as primary lymphoid cells.
VE:
1 * 10 µG
Artikel-Nr:
(PRSIXP-5218)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XP-5218
Lokale Artikelnummer::
PRSIXP-5218
Beschreibung:
Anti-CCL2 Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI76-756)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-756
Lokale Artikelnummer::
PRSI76-756
Beschreibung:
The 156-4H9 monoclonal antibody specifically reacts with human CD48, a GPI-linked glycoprotein in the Ig superfamily. CD48 was previously known as BCM1 in mice, Blast-1 in humans, and OX-45 in rats. Its ligands are CD2 and CD244 and it is expressed on leukocytes to the exclusion of non-hematopoietic cells and its expression increases in B cells upon activation.
VE:
1 * 0,05 mg
New Product
Artikel-Nr:
(PRSI31-103)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
31-103
Lokale Artikelnummer::
PRSI31-103
Beschreibung:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the gaba/benzodiazepine receptor and opening an integral chloride channel.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI92-646)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-646
Lokale Artikelnummer::
PRSI92-646
Beschreibung:
T cell immunoglobulin and mucin domain-3 (TIM3), also called hepatitis A virus cellular receptor 2 (HAVCR2), is a transmembrane glycoprotein of the TIM family of immune regulating molecules and plays an important role in the Th1-mediated immune response. TIM3 is expressed on the Th1 cells, CD8 T-cells, monocytes, and dendritic cells, but not on Th2 cells. TIM3 expressed by monocytes and dendritic cells facilitates phagocytosis of apoptotic cells and up-regulates cross-presentation of apoptotic cell-associated antigens through interaction with phosphatidylserine. Engagement of TIM3 by its ligand galectin-9 induces a range of immunosuppressive functions which enhance immune tolerance and inhibit anti-tumour immunity. Stimulation of TIM3 with an agonistic antibody promotes inflammation through the activation of innate immune cells. TIM3 is also regarded as a potential target molecule for immunotherapy. TIM3 and programmed cell death 1 (PD-1) as two important coinhibitory regulators of T cell responses, have been implicated with the T-cell dysfunction or exhaustion associated with chronic HBV infection including HBV-related HCC.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI23-915)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
23-915
Lokale Artikelnummer::
PRSI23-915
Beschreibung:
Anti-CTAG1B Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI26-414)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-414
Lokale Artikelnummer::
PRSI26-414
Beschreibung:
IL22 belongs to the IL-10 family. It is a cytokine that contributes to the inflammatory response in vivo.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI29-888)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-888
Lokale Artikelnummer::
PRSI29-888
Beschreibung:
ADH4, class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole.This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI45-487)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-487
Lokale Artikelnummer::
PRSI45-487
Beschreibung:
Anti-DLC1 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI92-580)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-580
Lokale Artikelnummer::
PRSI92-580
Beschreibung:
Kallikrein7, also named as stratum corneum chymotryptic enzyme (SCCE), is a secreted protein of the Kallikrein-related peptidase (KLK) family. This family contains fifteen homologous secreted serine endopeptidases and plays a significant role in various physiological processes, including skin desquamation, semen liquefaction, neural plasticity, and body fluid homeostasis. In skin KLK5, KLK 7 and KLK14 are able to degrade corneodesmosomes, which leads to desquamation of skin surface cells. KLK activation is believed to be mediated through highly organised proteolytic cascades, regulated through a series of feedback loops, inhibitors, auto-degradation and internal cleavages. Studies have shown that one potential physiological activator for KLK7 is KLK5. Along with KLK14, these three kallikreins form a proteolytic cascade in the stratum corneum. KLK7 is primarily expressed in the skin but is also detected at relatively high levels in oesophagus, heart, liver, central nervous system, kidney, pancreas, mammary and salivary glands.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI22-473)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
22-473
Lokale Artikelnummer::
PRSI22-473
Beschreibung:
Anti-TLK2 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI7391)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7391
Lokale Artikelnummer::
PRSI7391
Beschreibung:
AKT1S1 Antibody: The Akt signaling pathway contributes to the regulation of apoptosis after a variety of cell death signals. AKT1S1, also known as PRAS40, is a proline-rich substrate of the kinase AKT1 and is thought to play a role in neuroprotection mediated by nerve growth factor (NGF) after transient focal cerebral ischemia. AKT1S1 is also a substrate and potential regulator of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Treatment with the insulin-like growth factor-1 (IGF1) can indusce the phosphorylation of AKT1S1 via the PI3K/AKT signaling pathway in PC12 cells.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI25-160)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-160
Lokale Artikelnummer::
PRSI25-160
Beschreibung:
TIPARP is a poly [ADP-ribose] polymerase using NAD+ as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor; repeated rounds of ADP-ribosylation leads to the formation of poly (ADPribose) chains on the protein, thereby altering the function of the target protein. TIPARP may play a role in the adaptative response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI79-466)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-466
Lokale Artikelnummer::
PRSI79-466
Beschreibung:
Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI6663P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6663P
Lokale Artikelnummer::
PRSI6663P
Beschreibung:
CASKIN2 peptide is used for blocking the activity of CASKIN2 antibody.
VE:
1 * 50 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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