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PROSCI
Artikel-Nr:
(PRSI51-414)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
51-414
Lokale Artikelnummer::
PRSI51-414
Beschreibung:
Anti-LDHA Mouse Monoclonal Antibody
VE:
1 * 50 µl
Artikel-Nr:
(PRSI29-688)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-688
Lokale Artikelnummer::
PRSI29-688
Beschreibung:
As a tumor suppressor, it blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI45-090)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-090
Lokale Artikelnummer::
PRSI45-090
Beschreibung:
Anti-MMP7 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI76-093)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-093
Lokale Artikelnummer::
PRSI76-093
Beschreibung:
The ICRF44 monoclonal antibody specifically reacts with the 165 kDa human adhesion glycoprotein CD11b, which forms, together with the 95 kDa CD18 (integrin beta 2) a complex known as Mac-1. CD11b is expressed on the surface of activated lymphocytes, a subset of natural killer cells, granulocytes, and monocytes. It functions as a receptor in cell-cell and cell-matrix interactions and as a receptor for iC3b, ICAM-1, ICAM-2, and ICAM-3 intercellular adhesion molecules.
VE:
1 * 25 Tests
New Product
Artikel-Nr:
(PRSI19-397)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
19-397
Lokale Artikelnummer::
PRSI19-397
Beschreibung:
Anti-PHB2 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI18-939)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
18-939
Lokale Artikelnummer::
PRSI18-939
Beschreibung:
Anti-TRAF7 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI22-005)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
22-005
Lokale Artikelnummer::
PRSI22-005
Beschreibung:
Anti-ELAVL3 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI63-927)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
63-927
Lokale Artikelnummer::
PRSI63-927
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:10~50. For IF starting dilution is: 1:10~50. For FACS starting dilution is: 1:10~50.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI79-423)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-423
Lokale Artikelnummer::
PRSI79-423
Beschreibung:
Kinase subunit of both mTORC1 and mTORC2, which regulate cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino-acids. Amino-acid-signaling to mTORC1 is mediated by Rag GTPases, which cause amino-acid-induced relocalization of mTOR within the endomembrane system. Growth factor-stimulated mTORC1 activation involves AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC1 phosphorylates and activates S6K1 at 'Thr-421', which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation. mTORC2 is also activated by growth factors, but seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'. mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657'.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI5145P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5145P
Lokale Artikelnummer::
PRSI5145P
Beschreibung:
TNFAIP3 peptide is used for blocking the activity of TNFAIP3 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-421)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-421
Lokale Artikelnummer::
PRSI90-421
Beschreibung:
CD200, also known as OX-2, is a 45 kDa transmembrane immunoregulatory protein that belongs to the immunoglobulin superfamily. CD200 is widely but not ubiquitously expressed. Its receptor (CD200R) is restricted primarily to mast cells, basophils, macrophages, and dendritic cells, which suggests myeloid cell regulation as the major function of CD200. CD200 knockout mice are characterised by increased macrophage number and activation and are predisposed to autoimmune disorders. In T cells, CD200 functions as a costimulatory molecule independent of the CD28 pathway. Several viruses encode CD200 homologs which are expressed on infected cells during the lytic phase. Like CD200 itself, viral CD200 homologs also suppress myeloid cell activity, enabling increased viral propagation.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI24-191)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-191
Lokale Artikelnummer::
PRSI24-191
Beschreibung:
Anti-CD2 Recombinant Antibody [Clone: YTH 655]
VE:
1 * 0,2 mg
New Product
Artikel-Nr:
(PRSI60-365)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
60-365
Lokale Artikelnummer::
PRSI60-365
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI23-172)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
23-172
Lokale Artikelnummer::
PRSI23-172
Beschreibung:
Anti-RRAGA Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI30-861)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-861
Lokale Artikelnummer::
PRSI30-861
Beschreibung:
KLC3 is a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria.This gene encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI30-194)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-194
Lokale Artikelnummer::
PRSI30-194
Beschreibung:
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. LMNB2 is one of the two B type proteins, B2.The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B2. This gene is in a head-to-tail orientation with the gene for the translocase of inner mitochondrial membrane 13 homolog gene.
VE:
1 * 50 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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