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PROSCI
Artikel-Nr:
(PRSI24-766)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-766
Lokale Artikelnummer::
PRSI24-766
Beschreibung:
Anti-CD74 Recombinant Antibody [Clone: LN-2]
VE:
1 * 0,2 mg
New Product
Artikel-Nr:
(PRSI6667)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6667
Lokale Artikelnummer::
PRSI6667
Beschreibung:
SPINK2 Antibody: Human serine proteinase inhibitor Kazal-type 2 (SPINK2) is required for maintaining normal spermatogenesis and potentially regulates serine protease-mediated apoptosis in male germ cells. It contains a typical kazal domain composed by six cysteine residues forming three disulfide bridges. SPINK2 functions as a trypsin/acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged in fertility. SPINK2 plays a role in the pathogenesis of hereditary and chronic pancreatitis.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI79-387)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-387
Lokale Artikelnummer::
PRSI79-387
Beschreibung:
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation
VE:
1 * 100 µG
Artikel-Nr:
(PRSI33-208)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-208
Lokale Artikelnummer::
PRSI33-208
Beschreibung:
This antibody recognises a ~90-95 kDa protein which is identified as cell surface Transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa. The antibody is highly specific to transferrin receptor and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of transferrin receptor. Its ligand is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI76-297)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-297
Lokale Artikelnummer::
PRSI76-297
Beschreibung:
The UCHT1 monoclonal antibody specifically reacts with the epsilon chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains gamma, delta, and epsilon chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction. Unlike HIT3a, another specific antibody of CD3, the UCHT1 antibody can stain both the surface and intracellular CD3 epsilon. The immobilized UCHT1 can cross-link with the TCR complex, enhancing cellular activation and proliferation.
VE:
1 * 25 Tests
New Product
Artikel-Nr:
(PRSI28-965)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-965
Lokale Artikelnummer::
PRSI28-965
Beschreibung:
ZNF17 is a new candidate transcription factor.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI33-959)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-959
Lokale Artikelnummer::
PRSI33-959
Beschreibung:
Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI26-097)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-097
Lokale Artikelnummer::
PRSI26-097
Beschreibung:
SKAP1 Is a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI22-199)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
22-199
Lokale Artikelnummer::
PRSI22-199
Beschreibung:
Anti-SFRP4 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI49-660)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
49-660
Lokale Artikelnummer::
PRSI49-660
Beschreibung:
Anti-CLDN7 Rabbit Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(PRSI26-788)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-788
Lokale Artikelnummer::
PRSI26-788
Beschreibung:
The exact function of OLFML2A is not known.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI79-179)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-179
Lokale Artikelnummer::
PRSI79-179
Beschreibung:
Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI90-463)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-463
Lokale Artikelnummer::
PRSI90-463
Beschreibung:
IL-1beta is produced by activated macrophages. IL-1beta stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1beta belongs to the IL-1 family of proteins that are involved in the inflammatory response. IL-1beta in most situations requires the inflammasome complex to be cleaved and secreted.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI25-971)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-971
Lokale Artikelnummer::
PRSI25-971
Beschreibung:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-939 AC125816.8 75932-76870 c
VE:
1 * 50 µG
Artikel-Nr:
(PRSI79-131)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-131
Lokale Artikelnummer::
PRSI79-131
Beschreibung:
General protein kinase capable of phosphorylating several known proteins. Phosphorylates TBC1D4. Signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), insulin and insulin-like growth factor I (IGF-I). Plays a role in glucose transport by mediating insulin-induced translocation of the GLUT4 glucose transporter to the cell surface. Mediates the antiapoptotic effects of IGF-I. Mediates insulin-stimulated protein synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462', thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1. Promotes glycogen synthesis by mediating the insulin-induced activation of glycogen synthase.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI90-355)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-355
Lokale Artikelnummer::
PRSI90-355
Beschreibung:
Nuclear NMNAT isoform. Catalyses the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. It can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Interacts with PARP-1/ARTD1. Protects against axonal degeneration following mechanical or toxic insults. Widely expressed.
VE:
1 * 50 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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