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28 361 results were found
PROSCI
Artikel-Nr:
(PRSI27-478)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-478
Lokale Artikelnummer::
PRSI27-478
Beschreibung:
Smad7 acts to functionally inactivate RB and de-repress E2F without blocking the activation of TbetaRI and the nuclear translocation of Smad2/3, allowing TGF-beta1 to exert effects in a cancer cell that is resistant to TGF-beta1-mediated growth inhibition.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI71-186)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
71-186
Lokale Artikelnummer::
PRSI71-186
Beschreibung:
Anti-ERP44 Rabbit Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(PRSI79-329)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-329
Lokale Artikelnummer::
PRSI79-329
Beschreibung:
Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI79-146)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-146
Lokale Artikelnummer::
PRSI79-146
Beschreibung:
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI63-189)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
63-189
Lokale Artikelnummer::
PRSI63-189
Beschreibung:
For WB starting dilution is: 1:500. For IHC-P starting dilution is: 1:10~50. For IF starting dilution is: 1:10~50.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI63-452)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
63-452
Lokale Artikelnummer::
PRSI63-452
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI23-728)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
23-728
Lokale Artikelnummer::
PRSI23-728
Beschreibung:
Anti-ZFP36L1 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI24-219)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-219
Lokale Artikelnummer::
PRSI24-219
Beschreibung:
Anti-MOPC21 Recombinant Antibody [Clone: MOPC-21]
VE:
1 * 0,2 mg
New Product
Artikel-Nr:
(PRSI23-335)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
23-335
Lokale Artikelnummer::
PRSI23-335
Beschreibung:
Anti-TNS3 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI23-041)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
23-041
Lokale Artikelnummer::
PRSI23-041
Beschreibung:
Anti-WDR45 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI76-717)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-717
Lokale Artikelnummer::
PRSI76-717
Beschreibung:
The RPA-T8 monoclonal antibody specifically reacts with the human CD8a molecule, a 32 kDa cell surface receptor expressed either as a heterodimer (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha) on the majority of thymocytes, a subpopulation of mature T cells, and natural killer cells. CD8 interacts with the major histocompatibility complex class I (MHC class I) molecules on antigen-presenting cells or epithelial cells. The RPA-T8 antibody reacts with 13 to 48% of peripheral lymphocytes, 80% of thymocytes, and a subset of natural killer cells. RPA-T8, OKT8, and HIT8a antibodies do not compete with each other for binding to peripheral leukocytes, meaning that that they do not recognize the same epitope or block each other by steric hindrance.
VE:
1 * 25 Tests
New Product
Artikel-Nr:
(PRSI76-595)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-595
Lokale Artikelnummer::
PRSI76-595
Beschreibung:
The IT2.2 antibody reacts with human CD86, also known as B7-2, an 80 kDa cell surface protein which is a ligand for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 can also bind a second B7 ligand known as CD80 (B7-1). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction/co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.The IT2.2 antibody may be used as a marker for CD86 expression on B cells, macrophages, and dendritic cells. It is reported to be cross-reactive with Rhesus, Cynomolgus and Common marmoset CD86.
VE:
1 * 100 Tests
New Product
Artikel-Nr:
(PRSI77-156)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
77-156
Lokale Artikelnummer::
PRSI77-156
Beschreibung:
The PK136 monoclonal antibody is specific for the mouse NK1.1, a receptor from the killer cell lectin-like receptor (KLR) family. Nk1.1 is an antigen encoded by the Klrb1c/NKR-P1C gene expressed by the natural killer cells of some selected strains of mice (C57BL, FVB/N, NZB) and encoded by the Klrb1b/NKR-P1B gene expressed on Swiss NIH and SJL mice. Pk136 binds to an epitope common to NKR-P1B and NKR-P1C.The Klrb1 is a family of type II transmembrane C-type lectin receptors. Klrb1c activates the NK-cell cytotoxicity, while Klrb1b inhibits it. PK136 is useful in defining the NK cells and the rare population of NK-T lymphocytes and specific cultured monocytes.
VE:
1 * 0,025 mg
New Product
Artikel-Nr:
(PRSI24-398)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-398
Lokale Artikelnummer::
PRSI24-398
Beschreibung:
Anti-CD28 Recombinant Antibody [Clone: 1C6]
VE:
1 * 0,2 mg
New Product
Artikel-Nr:
(PRSI76-201)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-201
Lokale Artikelnummer::
PRSI76-201
Beschreibung:
The MEL-14 monoclonal antibody specifically reacts with L- selectin (CD62L), a receptor with lectin-like and Epidermal Growth Factor-like domains. The weight of the CD62L molecules depend on their origin, 74 kDa on lymphocytes or 95 kDa on neutrophils. In the mouse organism, CD62L can be expressed by most thymocytes, on subsets of B and T lymphocytes, monocytes, eosinophils, and neutrophils. The L-selectin binds sulfated, fucosylated, and glycosylated glycoproteins (MadCAM-1, GLYCAM-1, and CD 34). It mediates the migration of lymphocytes to the site of inflammation and their return to the peripheral lymphoid tissues and to the HEV (high endothelial venules). In vitro, L-selectin inhibits this binding and the lymphocyte extravasation into peripheral lymph nodes. After cell activation, it is quickly shed by neutrophils and lymphocytes.
VE:
1 * 0,025 mg
New Product
Artikel-Nr:
(PRSI77-001)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
77-001
Lokale Artikelnummer::
PRSI77-001
Beschreibung:
The HMN3-133 monoclonal antibody specifically reacts with mouse Notch3, a single-pass transmembrane protein. After binding with its ligand, Notch3 receptor undergoes cleavage resulting in a Notch intracellular domain (NICD) molecule that eventually activates transcription in the nucleus. It is expressed on Treg cells and adult smooth muscle arterial cells.
VE:
1 * 0,1 mg
New Product
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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