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PROSCI
Artikel-Nr:
(PRSI76-175)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-175
Lokale Artikelnummer::
PRSI76-175
Beschreibung:
The VI-PL2 monoclonal antibody reacts with CD61, a type I integral transmembrane glycoprotein also known as integrin beta 3. CD61 forms a complex with CD41 (platelet gpIIb) and CD51 (integrin alphaV). It is expressed on osteoclasts, fibroblasts, platelets, macrophages, and megakaryocytes and appears to bind to fibronectin, vitronectin, thrombospondin, and fibrinogen and vWF. The VI-PL2 antibody is reported to be cross-reactive with baboon, rhesus, and cynomolgus.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(PRSI29-433)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-433
Lokale Artikelnummer::
PRSI29-433
Beschreibung:
The function remains unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI30-811)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-811
Lokale Artikelnummer::
PRSI30-811
Beschreibung:
ECT2 is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of ECT2 is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.The protein encoded by this gene is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI28-415)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-415
Lokale Artikelnummer::
PRSI28-415
Beschreibung:
ZNF665 is a new candidate transcription factor. Western blots using two different antibodies (ARP36042-T200 and ARP36043_T200) against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI28-078)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-078
Lokale Artikelnummer::
PRSI28-078
Beschreibung:
NSEP1 is a cell cycle stage-specific transcription factor important for cell proliferation. NSEP1 encodes a protein that correlates with P-glycoprotein expression in human breast carcinoma.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-098)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-098
Lokale Artikelnummer::
PRSI92-098
Beschreibung:
Pleckstrin Homology-Like Domain Family A Member 2 (PHLDA2) is a peripheral membrane protein that belongs to the PHLDA2 family. PHLDA2 is expressed in the placenta and adult prostate gland. In the placenta, it is present in all cells of the villous cytotrophoblast. PHLDA2 plays a role in regulating placenta growth. PHLDA2 may act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI22-484)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
22-484
Lokale Artikelnummer::
PRSI22-484
Beschreibung:
Anti-UQCRFS1 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI24-452)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-452
Lokale Artikelnummer::
PRSI24-452
Beschreibung:
Anti-GITR Recombinant Antibody [Clone: YGITR765]
VE:
1 * 0,2 mg
New Product
Artikel-Nr:
(PRSI91-936)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-936
Lokale Artikelnummer::
PRSI91-936
Beschreibung:
emaphorin-3A is a secreted protein which belongs to the semaphorin family. Semaphorins are a family of secreted and cell-bound signaling molecules defined by the presence of a common 500 aa Sema domain.This protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI62-692)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
62-692
Lokale Artikelnummer::
PRSI62-692
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI76-398)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-398
Lokale Artikelnummer::
PRSI76-398
Beschreibung:
The SN3 monoclonal antibody specifically reacts with human CD24, a 35 to 45 kDa molecule also known as the Heat Stable Antigen (HAS), Ly-52, Nectadrin. It can be used as a marker for distinguishing between lymphocyte developmental stages as its expression varies on T and B cells during differentiation. CD24 is also expressed on monocytes, dendritic cells, hematopoietic stem cells, epidermal Lagershans cells, and neurons.
VE:
1 * 100 Tests
New Product
Artikel-Nr:
(PRSI90-294)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-294
Lokale Artikelnummer::
PRSI90-294
Beschreibung:
BAFF is mainly produced by innate immune cells such as neutrophils, monocytes, macrophages, dendritic cells, follicular dendritic cells. T cells, activated B cells, some malignant B cells and also non-lymphoid cells like astrocytes, synoviocytes and epithelial cells can also produce BAFF. BAFF binds three distinct receptors (BAFF-R, TACI and BCMA) expressed predominantly on B cells, although activated T cells also express BAFF-R. BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. Besides its major role in B cell biology, BAFF co-stimulates activated T cells. Deregulated expression of BAFF leads to autoimmune disorders in mice. In humans, elevated levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases such as Sjoegren syndrome, Rheumatoid arthritis (RA), Multiple sclerosis (MS) and Systemic Lupus Erythematosus (SLE). BAFF has also increased levels in some lymphoid cancers. Processed human BAFF can either remain as a trimer, which is usual for TNF family ligands or assemble into 60-mer composed of 20 trimers. Mouse BAFF 60-mer has been identified in the serum of BAFF transgenic mice. Oligomerisation of BAFF 3-mer into 60-mer in human BAFF is prevented by mutation of His218, a residue critical for 3-mer-to-3-mer interactions, but not for receptor binding. Despite the predominant functional role of processed BAFF in vivo, membrane-bound BAFF might also play a role. Indeed, soluble BAFF (3-mer) can trigger BAFF-R but not TACI or BCMA, whereas oligomeric forms of BAFF (BAFF 60-mer), which mimic membrane-bound BAFF, activate all BAFF receptors.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI22-263)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
22-263
Lokale Artikelnummer::
PRSI22-263
Beschreibung:
Anti-CSNK1A1L Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI4081P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4081P
Lokale Artikelnummer::
PRSI4081P
Beschreibung:
BRSK1 peptide is used for blocking the activity of BRSK1 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI62-427)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
62-427
Lokale Artikelnummer::
PRSI62-427
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI29-516)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-516
Lokale Artikelnummer::
PRSI29-516
Beschreibung:
In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. DAZAP1 is a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL.In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. This gene encodes a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL. Two isoforms are encoded by transcript variants of this gene.
VE:
1 * 50 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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