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PROSCI
Artikel-Nr:
(PRSI38-150)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
38-150
Lokale Artikelnummer::
PRSI38-150
Beschreibung:
A novel cytokine related to IL2 and IL15 was recently identified and designated IL21. IL21 has been found to be a powerful growth factor for naive B cells. The receptor for IL21 (IL21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL21 signaling. Both IL21R and the gc are necessary for the IL21 function. IL21 and its receptor activate JAKSTAT signaling pathway. IL21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL21 plays a role in the proliferation and maturation of NK, B and T cell populations.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4933)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4933
Lokale Artikelnummer::
PRSI4933
Beschreibung:
JPH4 Antibody: Junctional complexes between the plasma membrane (PM) and endoplasmic/sarcoplasmic reticulum (ER/SR) are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Junctophilins (JPs) are important components of the junctional complexes. JPs are composed of a carboxy-terminal hydrophobic segment spanning the ER/SR membrane and a remaining cytoplasmic domain that shows specific affinity for the PM. Four JPs have been identified as tissue-specific subtypes derived from different genes: JPH1 is expressed in skeletal muscle, JPH2 is detected throughout all muscle cell types, and JPH3 and JPH4 are predominantly expressed in the brain. In the CNS, both JPH3 and JPH4 are expressed throughout neural sites and contribute to the subsurface cistern formation in neurons. Mice lacking both JPH3 and JPH4 subtypes exhibit serious symptoms such as impaired learning and memory and are accompanied by abnormal nervous functions.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI24-354)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-354
Lokale Artikelnummer::
PRSI24-354
Beschreibung:
Anti-RTN4RL1 Recombinant Antibody [Clone: M5]
VE:
1 * 0,2 mg
New Product
Artikel-Nr:
(PRSI24-189)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-189
Lokale Artikelnummer::
PRSI24-189
Beschreibung:
Anti-Siglec1 Recombinant Antibody [Clone: 3D6.112 (recombinant version)]
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(PRSI91-270)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-270
Lokale Artikelnummer::
PRSI91-270
Beschreibung:
Human Histone Chaperone ASF1A (ASF1A) belongs to the H3/H4 family of histone chaperone proteins. ASF1A is ubiquitously expressed in many cells and tissues, interacting with histones H3 and H4. ASF1A cooperates with Chromatin Assembly Factor 1 to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. In addition, ASF1A is necessary for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI62-756)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
62-756
Lokale Artikelnummer::
PRSI62-756
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI32-222)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
32-222
Lokale Artikelnummer::
PRSI32-222
Beschreibung:
Baculoviral IAP repeat-containing 5 (survivin).This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI22-913)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
22-913
Lokale Artikelnummer::
PRSI22-913
Beschreibung:
Anti-DTX2 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI92-238)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-238
Lokale Artikelnummer::
PRSI92-238
Beschreibung:
Mouse interleukin 13 (mIL-13) is a pleiotropic cytokine produced by activated Th2 cells. IL-13 induces B cell proliferation and immunoglobin production. It contains a four helical bundle with two internal disulfide bonds. Mouse IL13 shares 58% sequence identity with human protein and exhibits cross-species activity. IL13 signals via receptor IL13R (type2, IL4R) and activates STAT-6. IL13 initially binds IL-13R alpha1 with low affinity and triggers association of IL4R alpha, generating a high affinity heterodimeric receptor IL13R and eliciting downstream signals. IL13 also binds IL-13R alpha2 with high affinity, which plays a role in a negative feedback system of IL13 signalling. IL13 is an important mediator of allergic inflammation and disease.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI18-744)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
18-744
Lokale Artikelnummer::
PRSI18-744
Beschreibung:
Anti-MAT1A Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI28-296)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-296
Lokale Artikelnummer::
PRSI28-296
Beschreibung:
This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI91-797)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-797
Lokale Artikelnummer::
PRSI91-797
Beschreibung:
Angiotensinogen is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Genetic variations in Angiotensinogen are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in the encoding gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-505)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-505
Lokale Artikelnummer::
PRSI92-505
Beschreibung:
Human delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase(ECH1) is a member of the hydratase/isomerase superfamily and contains a C-terminal peroxisomal targeting sequence and localises to peroxisomes. ECH1 shows high sequence similarity to enoyl-CoA hydratases of several species, particularly within a conserved domain characteristic of these proteins. The rat orthologlocalises to the matrix of both the peroxisome and mitochondria.It can isomerize 3-trans, 5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. ECH1 plays an important role in the auxiliary step of the fatty acid beta-oxidation pathway.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI6507P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6507P
Lokale Artikelnummer::
PRSI6507P
Beschreibung:
SDHAF2 peptide is used for blocking the activity of SDHAF2 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI25-042)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-042
Lokale Artikelnummer::
PRSI25-042
Beschreibung:
The homeodomain-containing transcription factor NKX3-1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3-1 protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.The homeodomain-containing transcription factor NKX3A is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3A protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5977P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5977P
Lokale Artikelnummer::
PRSI5977P
Beschreibung:
BANP peptide is used for blocking the activity of BANP antibody.
VE:
1 * 50 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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