PROSCI
Artikel-Nr:
(PRSI5069)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5069
Lokale Artikelnummer::
PRSI5069
Beschreibung:
LRFN3 Antibody: LRFN3 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI25-481)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-481
Lokale Artikelnummer::
PRSI25-481
Beschreibung:
This protein interacts with methyl-CpG-binding protein-2 (MBD2; MIM 603547), a component of the MeCP1 histone deacetylase (HDAC) complex, and plays a role in DNA methylation and transcription repressionMIZF interacts with methyl-CpG-binding protein-2 (MBD2; MIM 603547), a component of the MeCP1 histone deacetylase (HDAC) complex, and plays a role in DNA methylation and transcription repression.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI30-554)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-554
Lokale Artikelnummer::
PRSI30-554
Beschreibung:
BTNL8 is a single-pass type I membrane protein. It belongs to the immunoglobulin superfamily, BTN/MOG family. BTNL8 contains 1 B30.2/SPRY domain and 1 Ig-like V-type domain. The exact function of BTNL8 remains unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-660)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-660
Lokale Artikelnummer::
PRSI91-660
Beschreibung:
Galectin-3(LGALS3) is also known as Galactose-specific lectin 3, Mac-2 antigen, Carbohydrate-binding protein 35, Laminin-binding protein and Galactoside-binding protein. LGALS3 is highly expressed in early stages of papillary carcinoma, and lowly during tumor progression. LGALS3 is probably forms homo- or heterodimers and secreted by a non-classical secretory pathway and associates with the cell surface. LGALS3 plays an important role during the acquisition of vasculogenic mimicry and angiogenic properties. LGLAS3 takes part in an immune regulator to inhibit T-cell immune responses and promote tumor growth, as a result providing a new mechanism for tumor immune tolerance.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI35-361)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
35-361
Lokale Artikelnummer::
PRSI35-361
Beschreibung:
Anti-Saccharomyces cerevisiae Rabbit Polyclonal Antibody
VE:
1 * 1 mL
Artikel-Nr:
(PRSI26-942)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-942
Lokale Artikelnummer::
PRSI26-942
Beschreibung:
TTC33 contains 3 TPR repeats. The function of the TTC33 protein remains unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI98-571)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
98-571
Lokale Artikelnummer::
PRSI98-571
Beschreibung:
Anti-Cd3e Hamster Monoclonal Antibody [clone: 500-A2] (PE (Phycoerythrin)-Cy5®)
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(PRSI29-407)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-407
Lokale Artikelnummer::
PRSI29-407
Beschreibung:
HNRPH3 belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes. Multiple alternative transcript variants seem to be present for this gene and some appear to have intronic regions in the mRNA. Presently, only two transcript variants are fully described.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI29-070)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-070
Lokale Artikelnummer::
PRSI29-070
Beschreibung:
GRHL3 is a member of the grainyhead family of transcription factors. GRHL3 interacts with leader-binding protein 32 (LBP-32) and brother of mammalian grainyhead (BOM), and may function as a transcription factor during development. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene encodes a member of the grainyhead family of transcription factors. The encoded protein interacts with leader-binding protein 32 (LBP-32) and brother of mammalian grainyhead (BOM), and may function as a transcription factor during development. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional transcript variants have been described, but their biological nature has not been determined.This gene encodes a member of the grainyhead family of transcription factors. The encoded protein interacts with leader-binding protein 32 (LBP-32) and brother of mammalian grainyhead (BOM), and may function as a transcription factor during development. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional transcript variants have been described, but their biological nature has not been determined.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI79-391)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-391
Lokale Artikelnummer::
PRSI79-391
Beschreibung:
CREB1 is a transcription factor that is a member of the bZIP family of DNA binding proteins. It binds as a homodimer to the CRE (cAMP-Responsive Element), an octameric palindrome containing a conserved core sequence, 5-prime-TGACG-3-prime. It consists of two transcript variants encoding respective isoforms produced by alternate splicing. It is mapped to 2q32.3-q34. It is phosphorylated by several protein kinases and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. CREB1 is crucial for the consolidation of long-term conditioned fear memories, but not for encoding, storage, or retrieval of these memories. It is required for the stability of reactivated or retrieved conditioned fear memories.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI91-420)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-420
Lokale Artikelnummer::
PRSI91-420
Beschreibung:
Ephrins-A3 belongs the Ephrins ligand family which involved in a variety of biological processes, especially in the nervous system and in erythropoiesis. It is shown that Ephrin-A3 is expressed in brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes. Ephrin-A3 has a GPI anchor following the extracellular sequence and a signal sequence of 22 amino acids. Ephrin-A3 can bind EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, EphA8 and EphB1. Futhermore, it is associated with tumor growth and metastasis.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI24-794)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-794
Lokale Artikelnummer::
PRSI24-794
Beschreibung:
Anti-CXCR2 Recombinant Antibody [Clone: HC2]
VE:
1 * 0,2 mg
New Product
Artikel-Nr:
(PRSI27-055)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-055
Lokale Artikelnummer::
PRSI27-055
Beschreibung:
The exact functions of CCDC96 remain unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI46-686)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
46-686
Lokale Artikelnummer::
PRSI46-686
Beschreibung:
Anti-MARCH7 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI45-314)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-314
Lokale Artikelnummer::
PRSI45-314
Beschreibung:
Anti-ACTL6A, ACTL6B Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI79-199)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-199
Lokale Artikelnummer::
PRSI79-199
Beschreibung:
Involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. May represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage-gated potassium channel protein Kv1.2. Its activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity. Involved in osmotic stress-dependent SNCA 'Tyr-125' phosphorylation.
VE:
1 * 100 µG
Preis auf Anfrage
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