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PROSCI


28 362  results were found

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Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 91-216
Lokale Artikelnummer:: PRSI91-216
Beschreibung:   L-Lactate Dehydrogenase B Chain (LDH-B) is a member of the lactate dehydrogenase family that consists of three members, LDH-A, LDH-B and LDH-C; members of this family function as powerful markers for germ cell tumors. LDH-B is an oxidoreductase that catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. It converts pyruvate to lactate when oxygen is absent or in short supply and it performs the reverse reaction during the Cori cycle in the liver. It is also called Hydroxybutyrate Dehydrogenase (HBD) due to its ability to catalyze the oxidation of hydroxybutyrate.
VE:  1 * 50 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 6081P
Lokale Artikelnummer:: PRSI6081P
Beschreibung:   ZIP1 peptide is used for blocking the activity of ZIP1 antibody.
VE:  1 * 50 µG
Artikel-Nr: (PRSI62-563)

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 62-563
Lokale Artikelnummer:: PRSI62-563
Beschreibung:   For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.
VE:  1 * 400 µl
New Product
Artikel-Nr: (PRSI92-609)

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 92-609
Lokale Artikelnummer:: PRSI92-609
Beschreibung:   Lipocalin-2, also known as Neutrophil Gelatinase-Associated Lipocalin (NGAL), is a secretory protein of the lipocalin superfamily. Lipocalin-2 contains a signal peptide that enables it to be secreted and form complexes with matrix metalloproteinase-9 (MMP-9) through disulphide bonds. Similar to other lipocalin family members, Lipocalin-2 is involved in diverse cellular processes, including the transport of small hydrophobic molecules, protection of MMP-9 from proteolytic degradation, and cell signalling. Furthermore, Lipocalin-2 can tightly bind to bacterial siderophore through a cell surface receptor, possibly serving as a potent bacteriostatic agent by sequestering iron, regulating innate immunity and protecting kidney epithelial cells from ischemia–reperfusion injury. This protein is mainly expressed in neutrophils and in lower levels in the kidney, prostate, and epithelia of the respiratory and alimentary tracts. Recent evidence also suggests its role as a biomarker for renal injury and inflammation.
VE:  1 * 50 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 4355P
Lokale Artikelnummer:: PRSI4355P
Beschreibung:   LGP2 peptide is used for blocking the activity of LGP2 antibody.
VE:  1 * 50 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 27-076
Lokale Artikelnummer:: PRSI27-076
Beschreibung:   TSPAN33 plays an important role in normal erythropoiesis. It has a role in the differentiation of erythroid progenitors.
VE:  1 * 50 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 30-841
Lokale Artikelnummer:: PRSI30-841
Beschreibung:   HUS1Bis most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. HUS1B can interact with the check point protein RAD1 but not with RAD9. Overexpression of HUS1B has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1.The protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1.
VE:  1 * 50 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: XP-5142BT
Lokale Artikelnummer:: PRSIXP-5142BT
Beschreibung:   Anti-Csf3 Rabbit Polyclonal Antibody (Biotin)
VE:  1 * 50 µG
Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 90-354
Lokale Artikelnummer:: PRSI90-354
Beschreibung:   Nuclear NMNAT isoform. Catalyses the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. It can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Interacts with PARP-1/ARTD1. Protects against axonal degeneration following mechanical or toxic insults. Widely expressed.
VE:  1 * 10 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 3499
Lokale Artikelnummer:: PRSI3499
Beschreibung:   Rheb Antibody: Rheb (Ras homolog enriched in brain) is an evolutionarily conserved member of the Ras family of small GTP-binding proteins originally found to be rapidly induced by synaptic activity in the hippocampus following seizure. While it is expressed at relatively high levels in the brain, Rheb is widely expressed in other tissues and may be induced by growth factor stimulation. Similar to other family members, Rheb triggers activation of the Raf-MEK-MAPK pathway. Biochemical and genetic studies demonstrate that Rheb has an important role in regulating the insulin/Target of rapamycin (TOR) signaling pathway. TOR is a serine/threonine protein kinase that acts as a sensor for ATP and amino acids, balancing the availability of nutrients with protein translation and cell growth. A dimeric protein complex termed TSC1/TSC2 indirectly inhibits TOR activity by inhibiting Rheb via the GAP activity of TSC2.
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 29-642
Lokale Artikelnummer:: PRSI29-642
Beschreibung:   Cytosolic and membrane-bound forms of glutathione S-transferase are two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. GSTM1 a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione.Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.
VE:  1 * 50 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 25-089
Lokale Artikelnummer:: PRSI25-089
Beschreibung:   Adaptor proteins are usually required for transcriptional activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter.TADA3L is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined.
VE:  1 * 50 µG
Artikel-Nr: (PRSI51-317)

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 51-317
Lokale Artikelnummer:: PRSI51-317
Beschreibung:   Anti-ETV4 Mouse Monoclonal Antibody
VE:  1 * 50 µl
Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 35-195
Lokale Artikelnummer:: PRSI35-195
Beschreibung:   Anti-Streptococcus Goat Polyclonal Antibody (HRP (Horseradish Peroxidase))
VE:  1 * 1 mL
Artikel-Nr: (PRSI42-230)

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 42-230
Lokale Artikelnummer:: PRSI42-230
Beschreibung:   Anti-TJP1 Goat Polyclonal Antibody
VE:  1 * 100 µG
Artikel-Nr: (PRSI46-721)

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 46-721
Lokale Artikelnummer:: PRSI46-721
Beschreibung:   Anti-TUSC3 Goat Polyclonal Antibody
VE:  1 * 100 µG
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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