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PROSCI
Artikel-Nr:
(PRSI1115)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
1115
Lokale Artikelnummer::
PRSI1115
Beschreibung:
RAIDD Antibody: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain (DD)-containing receptors, TNFR1 and Fas. The death signals are transduced by a group of DD-containing adapter molecules. A novel cell death adapter was recently identified by two independent groups and designated RAIDD (RIP-associated ICH-1/CED-3-homologous protein with DD) and CRADD (caspase and RIP adapter with DD)1, RAIDD contains a DD and a CARD (for caspase recruitment domain) which interact with RIP and caspase, respectively, to transduce death signals1, 3. RAIDD is constitutively expressed in many tissues and mediates apoptosis caused by Fas and TNFR-1.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI76-907)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-907
Lokale Artikelnummer::
PRSI76-907
Beschreibung:
The A7R34 monoclonal antibody specifically reacts with the mouse CD127, the alpha subunit of the IL-7 receptor, expressed by immature B lymphocytes in the bone marrow, CD4-/CD8-, CD4+, and CD8+ thymocytes, and by mature T lymphocytes at low levels. Mature T cells express CD117 at low levels in the periphery.The A7R34 antibody prevents the interaction between IL-7 and its receptor and the binding of mAb SB/199, which also recognizes mouse CD127.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(PRSI61-093)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
61-093
Lokale Artikelnummer::
PRSI61-093
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI4977P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4977P
Lokale Artikelnummer::
PRSI4977P
Beschreibung:
EBI3 peptide is used for blocking the activity of EBI3 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI29-915)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-915
Lokale Artikelnummer::
PRSI29-915
Beschreibung:
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. SLC22A2 is one of the three similar cation transporters. SLC22A2 contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption.Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption. Two transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI42-019)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
42-019
Lokale Artikelnummer::
PRSI42-019
Beschreibung:
Anti-Tankyrase Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI28-831)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-831
Lokale Artikelnummer::
PRSI28-831
Beschreibung:
SUPT6H may be functionally analogous to SPT6 and emb-5 and may therefore regulate transcription through establishment or maintenance of chromatin structure. Spt6 may also participates in the regulation of transcription by RNA polymerase II (RNAPII). Human Spt6 (hSpt6) is a classic transcription elongation factor that enhances the rate of RNAPII elongation. HSpt6 is capable of stimulating transcription elongation both individually and in concert with DRB sensitivity-inducing factor (DSIF).
VE:
1 * 100 µG
Artikel-Nr:
(PRSI25-263)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-263
Lokale Artikelnummer::
PRSI25-263
Beschreibung:
This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product. Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI25-240)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-240
Lokale Artikelnummer::
PRSI25-240
Beschreibung:
Voltage-gated sodium channels are essential for the generation and propagation of action potentials in striated muscle and neuronal tissues. Biochemically, they consist of a large alpha subunit and 1 or 2 smaller beta subunits, such as SCN1B. The alpha subunit alone can exhibit all the functional attributes of a voltage-gated Na+ channel, but requires a beta-1 subunit for normal inactivation kinetics.Voltage-gated sodium channels are essential for the generation and propagation of action potentials in striated muscle and neuronal tissues. Biochemically, they consist of a large alpha subunit and 1 or 2 smaller beta subunits, such as SCN1B. The alpha subunit alone can exhibit all the functional attributes of a voltage-gated Na+ channel, but requires a beta-1 subunit for normal inactivation kinetics.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI27-201)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-201
Lokale Artikelnummer::
PRSI27-201
Beschreibung:
The specific function of LYPD4 is not yet known.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI22-393)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
22-393
Lokale Artikelnummer::
PRSI22-393
Beschreibung:
Anti-NFKB1 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI34-078)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
34-078
Lokale Artikelnummer::
PRSI34-078
Beschreibung:
Glypican-3 is a proteoglycan that bears heparan sulfate. Inhibits the dipeptidyl peptidase activity of DPP4. May be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs. May play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. May regulate growth and tumor predisposition. [UniProt].
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI25-083)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-083
Lokale Artikelnummer::
PRSI25-083
Beschreibung:
ZNF391 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 9 C2H2-type zinc fingers. ZNF391 may be involved in transcriptional regulation.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI76-954)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-954
Lokale Artikelnummer::
PRSI76-954
Beschreibung:
The TY25 antibody reacts with mouse B7-DC (PD-L2), a 42 kDa glycoprotein of the B7 family of the immunoglobulin superfamily. B7-DC is expressed by macrophages, monocytes, and sub-populations of dendritic cells. B7-DC has similarities with the rest of the B7 family, but it does not bind to CD28/CD152. The receptor for B7-DC is PD-1, which contains an Immunoreceptor Tyrosine-based Inhibitory Motif (ITIM), and is expressed on activated B and T cells. The interaction between B7-DC and its receptor seems to downregulate immune responses. However, B7-DC seems to be a costimulator of T lymphocytes, reacting with a receptor different than PD-1. B7-DC can bind and stimulate dendritic cells. It is also the first B-7 ligand involved in bidirectional communication. The TY25 monoclonal antibody blocks the binding of B7-DC to its receptor (PD-1) and can be used for studying the interaction between the antigen presenting cells and T lymphocytes.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(PRSI29-476)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-476
Lokale Artikelnummer::
PRSI29-476
Beschreibung:
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI61-559)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
61-559
Lokale Artikelnummer::
PRSI61-559
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.
VE:
1 * 400 µl
New Product
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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