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PROSCI


28 361  results were found

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Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 25-666
Lokale Artikelnummer:: PRSI25-666
Beschreibung:   UPF3B is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The protein is one of two functional homologs to yeast Upf3p. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X. Two splice variants encoding different isoforms have been found for this gene.
VE:  1 * 50 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 26-710
Lokale Artikelnummer:: PRSI26-710
Beschreibung:   The specific function of TC2N is not yet known.
VE:  1 * 50 µG
Artikel-Nr: (PRSI42-300)

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 42-300
Lokale Artikelnummer:: PRSI42-300
Beschreibung:   Anti-IKZF4 Goat Polyclonal Antibody
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 28-248
Lokale Artikelnummer:: PRSI28-248
Beschreibung:   Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member and the KCNA5 gene product assemble into a heteromultimeric A-type channel that inactivates completely and is significantly faster than other A-type Kv channels.
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 63-167
Lokale Artikelnummer:: PRSI63-167
Beschreibung:   For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.
VE:  1 * 400 µl
New Product

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 96-117
Lokale Artikelnummer:: PRSI96-117
Beschreibung:   Human recombinant CD55 (from HEK293 cells)
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 28-735
Lokale Artikelnummer:: PRSI28-735
Beschreibung:   MED21 belongs to the Mediator complex subunit 21 family. It is the component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
VE:  1 * 50 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 28-204
Lokale Artikelnummer:: PRSI28-204
Beschreibung:   PHF11 contains two PHD zinc fingers and probably regulates transcription. Distinctive splice variants were expressed in immune tissues and cells.
VE:  1 * 50 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 42-922
Lokale Artikelnummer:: PRSI42-922
Beschreibung:   Anti-Pard3b Goat Polyclonal Antibody
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 90-010
Lokale Artikelnummer:: PRSI90-010
Beschreibung:   Nicotinamide phosphoribosyltransferase (Nampt; pre-B cell colony-enhancing factor; PBEF; Visfatin) is an 52kDa adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
VE:  1 * 50 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 5801P
Lokale Artikelnummer:: PRSI5801P
Beschreibung:   ATG101 peptide is used for blocking the activity of ATG101 antibody.
VE:  1 * 50 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 6761P
Lokale Artikelnummer:: PRSI6761P
Beschreibung:   FOXRED2 peptide is used for blocking the activity of FOXRED2 antibody.
VE:  1 * 50 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 7009
Lokale Artikelnummer:: PRSI7009
Beschreibung:   EED Antibody: The EED protein (WAIT-1 or WD protein associated with integrin cytoplasmic tails-1), also called embryonic ectoderm development, is a member of the superfamily of WD-40 repeat proteins and widely conserved polycomb group (PcG) family of proteins. The polycomb group (PcG) is a large and evolutionarily conserved set of genes whose products act in multimeric complexes to modify histones, which are then thought to cause stable and heritable states of transcriptional repression. EED shuttles between the nucleus and the plasma membrane and can interact with the cytoplasmic tail of integrin beta 7 subunit. EED exerted an antiviral activity at the late stage of HIV-1 replication.
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 91-802
Lokale Artikelnummer:: PRSI91-802
Beschreibung:   The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain, one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. SEMA4B negatively regulates basophil-mediated Th2 and humoral memory responses.
VE:  1 * 50 µG
Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 35-313
Lokale Artikelnummer:: PRSI35-313
Beschreibung:   Anti-Mycobacterium tuberculosis Rabbit Polyclonal Antibody
VE:  1 * 1 mL

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 27-330
Lokale Artikelnummer:: PRSI27-330
Beschreibung:   HOXB6 belongs to the homeobox family. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17.
VE:  1 * 50 µG
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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