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28 361 results were found
PROSCI
Artikel-Nr:
(PRSI92-397)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-397
Lokale Artikelnummer::
PRSI92-397
Beschreibung:
Tyrosine-protein kinase Mer (MERTK) is a single-pass type I membrane protein which belongs to the MER/AXL/TYRO3 receptor kinase family. MERTK include two fibronectin type-III domains, two Ig-like C2-type domains, and one tyrosine kinase domain. It can’t be expressed in normal B- and T-lymphocytes, but it is usually expressed in numerous neoplastic B- and T-cell lines. MERTK could regulate many physiological processes, such as cell survival, migration, differentiation. It was demonstrated that the MERTK plays critical role in the engulfment and efficient clearance of apoptotic cells, platelet aggregation, and cytoskeleton reorganisation. Not only these, it also plays an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signalling SOCS1 and SOCS3. In addition, MERTK could regulate rod outer segments fragments phagocytosis in the retinal pigment epithelium (RPE)， deficiency in MERTK are the cause of retinitis pigmentosa.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI6085P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6085P
Lokale Artikelnummer::
PRSI6085P
Beschreibung:
ZIP3 peptide is used for blocking the activity of ZIP3 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI62-265)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
62-265
Lokale Artikelnummer::
PRSI62-265
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI4513)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4513
Lokale Artikelnummer::
PRSI4513
Beschreibung:
LGI4 Antibody: The leucine-rich, glioma inactivated gene 4 (LGI4) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI4 have not been found to be associated with ADTLE. However, the LGI4 gene is located in a region linked to benign familial infantile convulsions. Further study revealed that a GC-to-AT polymorphism was correlated with childhood absence epilepsy. Other studies showed that decreasing LGI4 expression in cultured cells inhibits myelination, indicating that LGI4 may play a role in neural development.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI48-348)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
48-348
Lokale Artikelnummer::
PRSI48-348
Beschreibung:
Anti-DPP4 Rabbit Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(PRSI45-015)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-015
Lokale Artikelnummer::
PRSI45-015
Beschreibung:
Anti-BAG2 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI96-361)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-361
Lokale Artikelnummer::
PRSI96-361
Beschreibung:
Glycoprotein A33 (GPA33) is also known as Cell surface A33 antigen, is a single-pass type I membrane protein which is expressed in normal gastrointestinal epithelium and in 95% of colon cancers. GPA33 The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily, which contains. GPA33 may play a role in cell-cell recognition and signaling.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI28-386)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-386
Lokale Artikelnummer::
PRSI28-386
Beschreibung:
PHF20 is a possible transcription factor.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI27-755)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-755
Lokale Artikelnummer::
PRSI27-755
Beschreibung:
The ZNF537 gene is located on chromosome 19.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5685P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5685P
Lokale Artikelnummer::
PRSI5685P
Beschreibung:
TMEM184C peptide is used for blocking the activity of TMEM184C antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI48-404)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
48-404
Lokale Artikelnummer::
PRSI48-404
Beschreibung:
ITGA2 encodes integrin alpha chain 2. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing alpha integrin 2 combines with beta integrin 1 to form a collagen-binding integrin referred to as glycoprotein Ia/IIa when expressed on platelets, and very late (activation) antigen 2 ('VLA-2') when found on T-cells. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI70-440)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
70-440
Lokale Artikelnummer::
PRSI70-440
Beschreibung:
Anti-MARK2 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
Artikel-Nr:
(PRSI27-366)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-366
Lokale Artikelnummer::
PRSI27-366
Beschreibung:
ELL encodes an RNA polymerase II transcription factor that undergoes frequent translocation in acute myeloid leukemia (AML). In addition to its elongation activity, ELL contains a novel type of RNA polymerase II interaction domain that is capable of repressing polymerase activity in promoter-specific transcription. EAP30 is a subunit of the ELL complex. EAP30 can interact with ELL and derepress ELL's inhibitory activity in vitro.SNF8, VPS25 (MIM 610907), and VPS36 (MIM 610903) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8, VPS25, and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL; MIM 600284) (Slagsvold et al., 2005 [PubMed 15755741]; Kamura et al., 2001 [PubMed 11278625]).
VE:
1 * 50 µG
Artikel-Nr:
(PRSI25-702)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-702
Lokale Artikelnummer::
PRSI25-702
Beschreibung:
CKM is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. CKM is a member of the ATP: guanido phosphotransferase protein family.The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-300)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-300
Lokale Artikelnummer::
PRSI91-300
Beschreibung:
CD55 is a member of the RCA (regulators of complement activation) family. RCA proteins is characterized by the presence of four to 30 SCRs (short consensus repeats also called CCPs for control protein modules) in their plasmaexposed regions. CD55 containing four SCR modules is involved in the regulation of the complement cascade. CD55 is known to bind CD97 via the first SCR. It also binds physiologically generated C3 convertases with its second and third SCRs. Binding results in an accelerated “decay”, or dissociation of active C3 convertases, thus blocking the development of C’ attack complexes on nonforeign cells. It is known that viruses and bacteria also utilize multiple SCR sites for infection.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI42-849)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
42-849
Lokale Artikelnummer::
PRSI42-849
Beschreibung:
Anti-OXER1 Goat Polyclonal Antibody
VE:
1 * 100 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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