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5-Brom-2-fluor-4-nitrotoluol
Artikel-Nr:
(PRSI61-655)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
61-655
Lokale Artikelnummer::
PRSI61-655
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI27-838)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-838
Lokale Artikelnummer::
PRSI27-838
Beschreibung:
Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR4 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in fetal and adult brain and lung.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI28-837)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-837
Lokale Artikelnummer::
PRSI28-837
Beschreibung:
TEF (thyrotroph embryonic factor) is a member of the PAR bZip (proline and acidic amino acid-rich basic leucine zipper) transcription factor family. It accumulates with robust circadian rhythms in tissues with high amplitudes of clock gene expression.Thyrotroph embryonic factor (TEF), a transcription factor, is a member of the PAR (proline and acidic amino acid-rich) subfamily of basic region/leucine zipper (bZIP) transcription factors. It is expressed in a broad range of cells and tissues in adult animals, however, during embryonic development, TEF expression appears to be restricted to the developing anterior pituitary gland, coincident with the appearance of thyroid-stimulating hormone, beta (TSHB). Indeed, TEF can bind to, and transactivate the TSHB promoter. It shows homology (in the functional domains) with other members of the PAR-bZIP subfamily of transcription factors, which include albumin D box-binding protein (DBP), human hepatic leukemia factor (HLF) and chicken vitellogenin gene-binding protein (VBP); VBP is considered the chicken homologue of TEF. Different members of the subfamily can readily form heterodimers, and share DNA-binding, and transcriptional regulatory properties.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI35-437)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
35-437
Lokale Artikelnummer::
PRSI35-437
Beschreibung:
Anti-Respiratory Syncytial Virus Mouse Monoclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI27-589)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-589
Lokale Artikelnummer::
PRSI27-589
Beschreibung:
SIRT6 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by SIRT6 is included in class IV of the sirtuin family.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI26-984)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-984
Lokale Artikelnummer::
PRSI26-984
Beschreibung:
Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG4.Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG4 (Ungar et al., 2002 [PubMed 11980916]).
VE:
1 * 50 µG
Artikel-Nr:
(PRSI36-040)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
36-040
Lokale Artikelnummer::
PRSI36-040
Beschreibung:
ANGPTL4 mainly expressed in endothelial cells (hypoxia-induced). Regulates angiogenesis and modulates tumorgenesis and directly regulates lipid, glucose, and energy metabolism. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 is a protein consisting of an N-terminal coiled-coil domain and a C-terminal fibrinogen-like domain (FLD). Both domains have distinct biological functions. The coiled-coil domain is responsible for the inhibitory effects on lipoprotein lipase (LPL) converting the active form of LPL into an inactive form, and the FLD domain mediates its antiangiogenic functions. The coiled coil and the FLD domains are separated by a short linker that can be cleaved after secretion. ANGPTL4 appears on the cell surface as the full-length form, where it can be released by heparin treatment. ANGPTL4 protein is then proteolytically cleaved by proprotein convertases (PCs), including furin, PC5/6, paired basic amino acid-cleaving enzyme 4, and PC7.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI25-583)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-583
Lokale Artikelnummer::
PRSI25-583
Beschreibung:
JMJD3 is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It plays a central role in regulation of posterior development, by regulating HOX gene expression. It is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI25-865)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-865
Lokale Artikelnummer::
PRSI25-865
Beschreibung:
RNF182 is a multi-pass membrane protein. It contains 1 RING-type zinc finger. The function of RNF182 remains unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI28-018)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-018
Lokale Artikelnummer::
PRSI28-018
Beschreibung:
The protein encoded by SMARCB1 is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. SMARCB1 has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-225)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-225
Lokale Artikelnummer::
PRSI92-225
Beschreibung:
tumour necrosis factor ligand superfamily member 9, also known as 4-1BBL, is a member of the the tumour necrosis factor family. It is a 254 amino acids cytokine that is expressed in brain, placenta, lung, skeletal muscle and kidney. TNFSF9 has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells, and is thought to be involved in T cell-tumour cell interaction.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5993P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5993P
Lokale Artikelnummer::
PRSI5993P
Beschreibung:
KPNA7 peptide is used for blocking the activity of KPNA7 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-682)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-682
Lokale Artikelnummer::
PRSI92-682
Beschreibung:
Triggering receptor expressed on myeloid cells-2 (TREM-2) is a cell surface receptor primarily expressed on macrophages, osteoclasts, microglia and dendritic cells. TREM-2 is one member of the TREM family, inhibiting the releasing of inflammatory mediators, so it is an important in vivo anti-inflammatory receptor. TREM-2 consists of an 18 aa signal sequence, a 153 aa extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane (TM) domain, and a 35 aa cytoplasmic tail. A soluble form of TREM-2 (TREM-2b) created by alternate splicing diverges at aa 161. TREM-2 transduces intracellular signals through the adaptor DAP12. After binding of TREM-2 with ligand, the TREM-2/DAP12 (dead-cell-activated-receptor-associated protein)-mediated signal transduction pathway causes a series of intracellular protein tyrosine phosphorylation reactions and enzymatic reactions, which then activate the myeloid cells and participate T cell responses.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI79-603)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-603
Lokale Artikelnummer::
PRSI79-603
Beschreibung:
May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI24-497)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-497
Lokale Artikelnummer::
PRSI24-497
Beschreibung:
Anti-INSR Recombinant Antibody [Clone: Fab 83-7]
VE:
1 * 0,2 mg
New Product
Artikel-Nr:
(PRSI76-691)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-691
Lokale Artikelnummer::
PRSI76-691
Beschreibung:
Anti-Cd8a Rat Monoclonal Antibody [clone: 53-6.7] (PE (Phycoerythrin)-Cy5®)
VE:
1 * 0,025 mg
New Product
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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