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PROSCI
Artikel-Nr:
(PRSI46-579)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
46-579
Lokale Artikelnummer::
PRSI46-579
Beschreibung:
Anti-VPS26A Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI10-877)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
10-877
Lokale Artikelnummer::
PRSI10-877
Beschreibung:
Anti-RG7716 Recombinant Antibody
VE:
1 * 0,1 mg
Artikel-Nr:
(PRSI25-027)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-027
Lokale Artikelnummer::
PRSI25-027
Beschreibung:
SOX1 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. SOX1 may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development.This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5185)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5185
Lokale Artikelnummer::
PRSI5185
Beschreibung:
NPC1 Antibody: Mutations in the Niemann-Pick disease type C1 (NPC1) gene result in a fatal progressive neurodegenerative disorder characterized by an abnormal sequestration of lipids including cholesterol and glycosphingolipids. The NPC1 protein is a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. NPC1 transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. NPC1, in addition to FTO, MC4R, and PTER has recently been shown to be a new risk loci for early-onset and morbid adult obesity in European populations. This anti-NPC1 antibody will not cross-react to NPC2, another gene whose defects also result in Niemann-Pick type C disease.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI25-316)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-316
Lokale Artikelnummer::
PRSI25-316
Beschreibung:
HOXB8 belongs to the Antp homeobox family. It is a nuclear protein with a homeobox DNA-binding domain. This gene is included in a cluster of homeobox B genes located on chromosome 17. The protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-482)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-482
Lokale Artikelnummer::
PRSI92-482
Beschreibung:
Mouse Ca14,also known as Carbonic anhydrase 14,is a member of large family of zinc metalloenzymes. It could catalyse reversible hydration of carbon dioxide. The reaction is fundamental to many processes such as respiration, renal tubular acidification and bone resorption. Fifteen CA isoforms have been reported so far. They have different patterns of tissue-specific expression and physiologic roles. Some CAs may serve as markers for tumours and hypoxia. CA XIV is a polypeptide consisting of an extracellular N-terminal catalytic domain, a membrane-spanning segment and a short intracellular C- terminal segment with several potential phosphorylation sites. A subset of CAs lack CA activity due to point mutations but retain esterase function. CA14 is widely expressed in the central nervous system.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI61-338)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
61-338
Lokale Artikelnummer::
PRSI61-338
Beschreibung:
For WB starting dilution is: 1:2000.
VE:
1 * 200 µl
New Product
Artikel-Nr:
(PRSI19-483)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
19-483
Lokale Artikelnummer::
PRSI19-483
Beschreibung:
Anti-CDC37L1 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI23-652)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
23-652
Lokale Artikelnummer::
PRSI23-652
Beschreibung:
Anti-HOXA10 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI5721)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5721
Lokale Artikelnummer::
PRSI5721
Beschreibung:
APC2 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC2 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. Like APC11, APC2 contains cullin and RING finger domains that are thought to be important in regulating ubiquitination activity.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI25-989)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-989
Lokale Artikelnummer::
PRSI25-989
Beschreibung:
RP11-50D16.3 contains 4 NHL repeats. The function of the RP11-50D16.3 protein remains unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI79-518)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-518
Lokale Artikelnummer::
PRSI79-518
Beschreibung:
Tau is a heterogeneous microtubule-associated protein that promotes and stabilizes microtubule assembly, especially in axons. Six isoforms with different amino-terminal inserts and different numbers of tandem repeats near the carboxy-terminus have been identified, and tau is hyperphosphorylated at approximately 25 sites by ERK, GSK-3 and CDK5. Phosphorylation decreases the ability of tau to bind to microtubules. Neurofibrillary tangles are a major hallmark of Alzheimer's disease and these tangles are bundles of paired helical filaments composed of hyperphosphorylated tau. In particular, phosphorylation of Ser396 by GSK-3 or CDK5 destabilizes microtubules in Alzheimer's disease. Furthermore, inclusions of tau are found in a number of other neurodegenerative diseases, collectively known as tauopathies (1, 3).
VE:
1 * 100 µG
Artikel-Nr:
(PRSI28-014)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-014
Lokale Artikelnummer::
PRSI28-014
Beschreibung:
The protein encoded by the RFP2 gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies near the nucleus, but its function is unknown. The gene is located on chromosome 13 within the minimal deletion region for B-cell chronic lymphocytic leukemia.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI30-987)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-987
Lokale Artikelnummer::
PRSI30-987
Beschreibung:
PCDH17 contains six extracellular cadherin domains, a transmembrane domain, and a cytoplasmic tail differing from those of the classical cadherins.It may play a role in the establishment and function of specific cell-cell connections in the brain.This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein contains six extracellular cadherin domains, a transmembrane domain, and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein may play a role in the establishment and function of specific cell-cell connections in the brain.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI7445)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7445
Lokale Artikelnummer::
PRSI7445
Beschreibung:
Kallikreins (KLKs) belong to the serine protease family of proteolytic enzymes having diverse physiological functions. Kallikrein 4 (KLK4), also known as prostase or EMSP1 (enamel matrix serine protease 1), contains one peptidase S1 domain and the expression in prostate is regulated by hormone (1,2). Many kallikreins are implicated in carcinogenesis and have potential as novel cancer and other disease biomarkers. KLK4 may have additional roles such as functioning as one of the two major enamel proteases identified that process enamel matrix proteins. Defects in KLK4 are the cause of amelogenesis imperfecta hypomaturation type 2A1 (AI2A1).
VE:
1 * 100 µG
Artikel-Nr:
(PRSI7541)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7541
Lokale Artikelnummer::
PRSI7541
Beschreibung:
COMMD7 (COMM domain-containing protein 7) plays a role in the regulation NF-kappaB. It associates with the NF-kB complex and suppresses its transcriptional activity. COMMD7 contains 1 COMM domain and widely expressed with highest expression in lung. COMMD7 is a newly identified gene overexpressed in hepatocellular carcinoma (HCC). COMMD7 is associated with tumor invasion and poor prognosis by NF-kappaB signaling pathway.
VE:
1 * 100 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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