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PROSCI
Artikel-Nr:
(PRSI7021)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7021
Lokale Artikelnummer::
PRSI7021
Beschreibung:
PHLPP2 Antibody: PHLPP2 is a member of the serine/threonine phosphatase family, which are important regulators of Akt serine-threonine kinases (AKT1, AKT2, AKT3) and conventional/novel protein kinase C (PKC) isoforms. PHLPP1 and PHLPP2 have a similar domain structure and have been shown to dephosphorylate and inactivate, distinct Akt isoforms, at one of the two critical phosphorylation sites required for activation: Serine473. PHLPP2 dephosphorylates AKT1 and AKT3, whereas PHLPP1 is specific for AKT2 and AKT3. PHLPP1 promotes apoptosis and may act as a tumor suppressor. PHLPP2 associates with and is inhibited by adenylyl cyclase type 6 (AC6), thereby allowing Akt activation.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI91-635)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-635
Lokale Artikelnummer::
PRSI91-635
Beschreibung:
Mouse beta -NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. beta -NGF is a potent neurotrophic factor that signals through its receptor beta -NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. beta -NGF also acts as a growth and differentiation factor for B lymphocytes, and enhances B-cell survival.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI19-643)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
19-643
Lokale Artikelnummer::
PRSI19-643
Beschreibung:
Anti-DLD Rabbit Polyclonal Antibody
VE:
1 * 50 µl
Artikel-Nr:
(PRSI76-253)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-253
Lokale Artikelnummer::
PRSI76-253
Beschreibung:
The OKT3 monoclonal antibody specifically reacts with the epsilon chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains gamma, delta, and epsilon chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.The OKT3 antibody is an immunosuppressive, which has proven to be an effective therapeutic agent in liver, heart, and renal allograft rejection.
VE:
1 * 100 Tests
New Product
Artikel-Nr:
(PRSI76-736)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-736
Lokale Artikelnummer::
PRSI76-736
Beschreibung:
The CD28.2 monoclonal antibody specifically binds with the human 44 kDa homodimeric trans-membrane glycoprotein CD28, expressed on the surface of most mature T lymphocytes, plasma cells, and thymocytes. CD28 is a ligand for B7-1 (CD80) and B7-2 (CD86), a co-stimulator of T lymphocytes, and enhances the interaction between T and B lymphocytes. It has been reported that the T lymphocytes stimulation to produce IL-2 depends on the monoclonal antibody involved, which suggests that the CD28 molecule presents some subregions with distinct functions. The CD28.2 antibody induces Ca2+ influx in Jurkat T lymphocytes. Other studies have shown that CD28 is involved in the signal transduction.
VE:
1 * 100 Tests
New Product
Artikel-Nr:
(PRSI5281P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5281P
Lokale Artikelnummer::
PRSI5281P
Beschreibung:
GALNT10 peptide is used for blocking the activity of GALNT10 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI24-019)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-019
Lokale Artikelnummer::
PRSI24-019
Beschreibung:
Anti-SLC2A13 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
Artikel-Nr:
(PRSI22-737)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
22-737
Lokale Artikelnummer::
PRSI22-737
Beschreibung:
Anti-IL22RA2 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
Artikel-Nr:
(PRSI28-858)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-858
Lokale Artikelnummer::
PRSI28-858
Beschreibung:
Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. SAP30 is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones.Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI28-981)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-981
Lokale Artikelnummer::
PRSI28-981
Beschreibung:
DUX5, an active gene of unusual structure, is present in chromosome regions characterized by large amounts of heterochromatic repetitive DNA.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI32-190)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
32-190
Lokale Artikelnummer::
PRSI32-190
Beschreibung:
Mitogen-activated protein kinase 11.The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI27-292)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-292
Lokale Artikelnummer::
PRSI27-292
Beschreibung:
TSC22D4 is a leucine zipper-containing protein that is highly conserved during evolution. It is transcriptionally up-regulated by many different stimuli, including anti-cancer drugs and growth inhibitors. TSC22D4 may play a suppressive role in tumorigenesis.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI25-630)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-630
Lokale Artikelnummer::
PRSI25-630
Beschreibung:
PIGK is a member of the cysteine protease family C13 that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. PIGK is a member of the multisubunit enzyme, GPI transamidase and is thought to be its enzymatic component. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. This gene encodes a member of the cysteine protease family C13 that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is a member of the multisubunit enzyme, GPI transamidase and is thought to be its enzymatic component. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4775)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4775
Lokale Artikelnummer::
PRSI4775
Beschreibung:
PRTFDC1 Antibody: Phosphoribosyl transferase domain containing 1 (PRTFDC1) is highly homologous to the hypoxanthine phosphoribosyltransferase (HPRT1) and may have arisen from a gene duplication event of a common ancestor gene. Recently, it was shown that CpG islands in the PRTFDC1 promoter could be hypermethylated in ovarian cancers and oral squamous-cell carcinomas (OSCC), leading to gene silencing. Restoration of PRTFDC1 expression in OSCC inhibited cell growth in colony-formation assays, while knockdown of PRTFDC1 expression in OSCC that expressed the gene promoted cell growth. These results suggest that PRTFDC1 can act as a tumor-suppressor gene. At least three isoforms of PRTFDC1 are known to exist.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI62-986)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
62-986
Lokale Artikelnummer::
PRSI62-986
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:10~50.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI31-122)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
31-122
Lokale Artikelnummer::
PRSI31-122
Beschreibung:
MCH may act as a neurotransmitter or neuromodulator in a broad array of neuronal functions directed toward the regulation of goal-directed behavior, such as food intake, and general arousal. May also have a role in spermatocyte differentiation.
VE:
1 * 100 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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