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Dimethyl+2,5-dibromoterephthalate
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Dimethyl+2,5-dibromoterephthalate
Lieferant:
FLUOROCHEM
Beschreibung:
1,3-Dimethyl-1H-pyrazol-4-carbaldehyd
Lieferant:
Thermo Scientific
Beschreibung:
(Dimethylamino)acetaldehyddimethylacetal 97%
Artikel-Nr:
(BOSSBS-0301R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0301R-A350
Lokale Artikelnummer::
BOSSBS-0301R-A350
Beschreibung:
Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation. Seems to be involved in gene silencing (By similarity). In association with DNMT1 and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9. Isoforms 4 and 5 are probably not functional due to the deletion of two conserved methyltransferase motifs. Function as transcriptional corepressor by associating with ZHX1.
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
(±)-2,2-Dimethyl-1,3-dioxolan-4-ylmethanol, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-5285R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5285R-A647
Lokale Artikelnummer::
BOSSBS-5285R-A647
Beschreibung:
Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' and activates transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C.
VE:
1 * 100 µl
Artikel-Nr:
(MOLE21833767-500G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
21833767-500G
Lokale Artikelnummer::
MOLE21833767-500G
Beschreibung:
(±)-2,2-Dimethyl-1,3-dioxolan-4-ylmethanol
VE:
1 * 500 g
 This is a MarketSource item. Additional charges may apply
Lieferant:
Sigma-Aldrich
Beschreibung:
1,3-Dimethyl-2-thioharnstoff, Sigma-Aldrich®
Lieferant:
Thermo Scientific
Beschreibung:
3,5-Dimethyl-1H-pyrazol-1-carboxamid
Lieferant:
COMBI-BLOCKS
Beschreibung:
4-Brom-3,5-dimethyl-1-(2-tetrahydropyranyl)-1H-pyrazol
Lieferant:
FLUOROCHEM
Beschreibung:
1,5-Dimethyl-1H-pyrazol-3-carbonsäure
Artikel-Nr:
(BOSSBS-9784R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9784R-A680
Lokale Artikelnummer::
BOSSBS-9784R-A680
Beschreibung:
C1orf25, also known as TRM1L (TRMT1-like protein), MST070 or MSTP070, is a 733 amino acid protein that belongs to the TRM1 family of proteins. Expressed in a wide variety of tissues, C1orf25 contains one C2H2-type zinc finger and shares sequence similarity with TRMT1, a tRNA methyltransferase that dimethylates guanine at position 26 of tRNAs. As is suggested by observations of C1orf25-deficient mice, C1orf25 is believed to play a role in exploratory behavior and motor coordination. The gene encoding C1orf25 localizes to chromosome 1 and, due to alternative splicing events, C1orf25 exists as at least two isoforms.
VE:
1 * 100 µl
Lieferant:
COMBI-BLOCKS
Beschreibung:
4-Brom-3,5-dimethyl-1H-pyrazol
Lieferant:
FLUOROCHEM
Beschreibung:
6,6,7,7,8,8,8-Heptafluor-2,2-dimethyl-3,5-octandion
Artikel-Nr:
(BOSSBS-5962R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5962R-A350
Lokale Artikelnummer::
BOSSBS-5962R-A350
Beschreibung:
Testis-specific DNA binding protein responsible for insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. Plays a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2. This probably leads to recruit de novo DNA methyltransferases at these sites (By similarity). Seems to act as tumor suppressor. In association with DNMT1 and DNMT3B, involved in activation of BAG1 gene expression by binding to its promoter. Required for dimethylation of H3 lysine 4 (H3K4me2) of MYC and BRCA1 promoters.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0724R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0724R
Lokale Artikelnummer::
BOSSBS-0724R
Beschreibung:
Chromatin reader that specifically recognizes and binds histone H3 both trimethylated at 'Lys-4' and asymmetrically dimethylated at 'Arg-8' (H3K4me3 and H3R8me2a) and acts as an activator of Wnt signaling pathway dowstream of PRMT2. In case of cancer, promotes cell cancer proliferation via activation of the Wnt signaling pathway (PubMed:24589551). Overexpression induces metaphase arrest and chromosomal instability. Localizes to active rDNA loci and promotes the expression of rRNA genes (PubMed:21960006). May play a role in cell-cycle regulation during the transition from gamete to embryo. Involved in oocyte meiotic resumption, a process that takes place before ovulation to resume meiosis of oocytes blocked in prophase I: may act by regulating maternal transcripts to control meiotic resumption.
VE:
1 * 100 µl
Artikel-Nr:
(FLUO014578-1G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
014578-1G
Lokale Artikelnummer::
FLUO014578-1G
Beschreibung:
4-Brom-1,5-dimethyl-1H-pyrazol-3-carbonsäure
VE:
1 * 1 g
This is a MarketSource item. Additional charges may apply
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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