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TONBO BIOSCIENCE
Artikel-Nr:
(50-8036-U100)
Lieferant:
Tonbo Biosciences
Hersteller-Artikelnummer::
50-8036-U100
Lokale Artikelnummer::
TNBO50-8036-U100
Beschreibung:
Goat anti-Rabbit IgG, secondary antibody, conjugated toSureLight® R-Phycoerythrin
VE:
1 * 100 µG
Artikel-Nr:
(72-8085-M001)
Lieferant:
Tonbo Biosciences
Hersteller-Artikelnummer::
72-8085-M001
Lokale Artikelnummer::
TNBO72-8085-M001
Beschreibung:
Donkey anti-Sheep IgG (H&L) - Affinity Pure, HRP Conjugate, min x w/human, mouse, or rabbit IgG
VE:
1 * 1 mg
Artikel-Nr:
(72-8120-M001)
Lieferant:
Tonbo Biosciences
Hersteller-Artikelnummer::
72-8120-M001
Lokale Artikelnummer::
TNBO72-8120-M001
Beschreibung:
Goat anti-Human IgG Fc - Affinity Pure, HRP Conjugate
VE:
1 * 1 mg
Artikel-Nr:
(70-8078-M002)
Lieferant:
Tonbo Biosciences
Hersteller-Artikelnummer::
70-8078-M002
Lokale Artikelnummer::
TNBO70-8078-M002
Beschreibung:
Sheep anti-Rabbit IgG (H&L) - Affinity Pure
VE:
1 * 2 mg
Artikel-Nr:
(72-8074-U500)
Lieferant:
Tonbo Biosciences
Hersteller-Artikelnummer::
72-8074-U500
Lokale Artikelnummer::
TNBO72-8074-U500
Beschreibung:
Goat anti-Rabbit IgG (H&L), F(ab')2 Fragment - Affinity Pure, HRP Conjugate, min x w/ bovine, human, or mouse IgG or serum proteins
VE:
1 * 0,5 mg
Artikel-Nr:
(22-8042-M001)
Lieferant:
Tonbo Biosciences
Hersteller-Artikelnummer::
22-8042-M001
Lokale Artikelnummer::
TNBO22-8042-M001
Beschreibung:
Goat anti-Mouse IgG (H&L) - Affinity Pure, Alkaline Phosphatase Conjugate
VE:
1 * 1 mg
Lieferant:
Tonbo Biosciences
Beschreibung:
The A20 antibody reacts with mouse CD45.1, also known as Ly5.1, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors.
Lieferant:
Tonbo Biosciences
Beschreibung:
The 3G3 antibody reacts with mouse Foxp3, a 50-55 kDa transcription factor which is a central regulator of T cell activity and is critical for the development and function of regulatory T cells (Tregs). Foxp3 is expressed at constitutively high levels in Treg cells, which are further identified as being CD4+ CD25+. In resting conventional T cells (CD4+ CD25-) Foxp3 expression is restricted, and upon TCR activation is expressed only transiently and in a small proportion of cells. However, the growth factor TGF-beta has been shown to induce expression of Foxp3 in naïve T cells, driving their development into Foxp3+ Tregs, which are called “induced” or “adaptive” Tregs. These cells are phenotypically similar to so-called “natural” Tregs (CD4+ CD25high Foxp3+) which originate in the thymus and comprise the majority of Treg cells. Tregs are critical for maintaining peripheral tolerance and are implicated in the development of autoimmunity.
Lieferant:
Tonbo Biosciences
Beschreibung:
The 2.4G2 antibody is specific for a common epitope found in the extracellular regions of mouse Fc-receptors Fc-gamma II (CD32) and Fc-gamma III (CD16). These receptors are expressed by B cells, monocytes, macrophages, NK cells, dendritic cells, and neutrophils.
Artikel-Nr:
(35-8023-M001)
Lieferant:
Tonbo Biosciences
Hersteller-Artikelnummer::
35-8023-M001
Lokale Artikelnummer::
TNBO35-8023-M001
Beschreibung:
Goat anti-Human IgA (alpha chain) - Affinity Pure, FITC Conjugate, min x w/bovine, mouse, and rabbit serum proteins
VE:
1 * 1 mg
Lieferant:
Tonbo Biosciences
Beschreibung:
The RPA-2.10 antibody reacts with human CD2, an approximately 50 kDa glycoprotein, and a member of the Ig superfamily. CD2, also known as LFA-2, is a receptor for CD58 in the human and is expressed on the cell surface of 80-90% of human peripheral blood lymphocytes, a subset of NK cells, and all mature T cells. CD2 mediates lymphocyte adhesion and is involved in T cell activation.
Lieferant:
Tonbo Biosciences
Beschreibung:
The RPA-2.10 antibody reacts with human CD2, an approximately 50 kDa glycoprotein, and a member of the Ig superfamily. CD2, also known as LFA-2, is a receptor for CD58 in the human and is expressed on the cell surface of 80-90% of human peripheral blood lymphocytes, a subset of NK cells, and all mature T cells. CD2 mediates lymphocyte adhesion and is involved in T cell activation.
Artikel-Nr:
(67-4714-U100)
Lieferant:
Tonbo Biosciences
Hersteller-Artikelnummer::
67-4714-U100
Lokale Artikelnummer::
TNBO67-4714-U100
Beschreibung:
The MOPC-21 immunoglobulin is useful as an isotype-matched control. The MOPC-21 immunolglobulin has an unknown binding specificity and is used as an isotype control for mouse IgG1 antibodies.
VE:
1 * 100 µG
Lieferant:
Tonbo Biosciences
Beschreibung:
The RA3-6B2 antibody reacts with the human and mouse CD45 isoform known as CD45R, or B220, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns, all critical for leukocyte function. In mouse, the CD45R/B220 isoform is predominantly found on B cells, at varying levels on all stages from pro-B cells to activated B cells, and may also be detected on certain T cell and NK cell subsets. It is of note that B220 is not similarly expressed on human B cells, where it appears to be differentiation-specific and therefore expressed on only some B cell subsets. Other forms of CD45 with restricted cellular expression include CD45RA, CD45RB, CD45RO and several others. The RA3-6B2 antibody is one of the most consistently used leukocyte markers for B cells, T cell subsets and NK cell subsets in human and mouse. This antibody has also been reported as cross-reactive with feline CD45R/B220.
Lieferant:
Tonbo Biosciences
Beschreibung:
The H57-597 antibody is specific for the beta chain of the mouse T cell Receptor (TCR). This cell surface protein combines with a second protein chain (alpha chain) to form the alpha-beta TCR that is expressed by NK1.1+ thymocytes, NKT cells, and the majority of peripheral T cells. A small number of T cells may express an alternative heteromer of gamma/delta protein chains, known as the g/d TCR. These receptors participate in a complex with CD3, and with the co-receptors CD4 or CD8, to recognize and respond to antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death.</p><p>The H57-597 antibody is used as a phenotypic marker for T cells expressing the alpha-beta TCR. It is also widely used to cross-link surface TCR and thereby mimic TCR-mediated cell activation or induction of apoptosis. The antibody does not cross-react with cells expressing the g/d TCR.
Lieferant:
Tonbo Biosciences
Beschreibung:
The M5/114.15.2 antibody reacts with mouse MHC Class II alloantigens I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek, as well as being cross-reactive with mouse cells of H-2p and H-2r haplotype. MHC Class II is widely expressed by mouse immune cells bearing these alloantigens, including T and B cells, monocytes, macrophages, and dendritic cells. The antibody does not react with the following alloantigens: I-Af, I-Ak, I-As, or NOD H-2g7. The M5/114.15.2 antibody may be used for analysis of mouse cells expressing MHC Class II alloantigens as described. Please note that the M5/114.15.2 clone may also be referred to as M5/114 in the literature.
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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