Drucken
Sie suchten nach:
432 010 results were found
Antikörper
Artikel-Nr:
(BOSSBS-12299R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12299R-FITC
Lokale Artikelnummer::
BOSSBS-12299R-FITC
Beschreibung:
RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis (By similarity). RNA-binding protein that seems to act as a coregulatory factor of ER-alpha.
VE:
1 * 100 µl
Artikel-Nr:
(USBI124610)
Lieferant:
US Biological
Hersteller-Artikelnummer::
124610
Lokale Artikelnummer::
USBI124610
Beschreibung:
Anti-FCGR2A Mouse Monoclonal Antibody [clone: 3E8]
VE:
1 * 100 µG
Lieferant:
Biotium
Beschreibung:
The epitope of this MAb maps in the C-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2 levels by dissolving the salts in bone and preventing their renal excretion.It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
Artikel-Nr:
(USBIL2048-03)
Lieferant:
US Biological
Hersteller-Artikelnummer::
L2048-03
Lokale Artikelnummer::
USBIL2048-03
Beschreibung:
Anti-Leumorphin Rabbit Polyclonal Antibody
VE:
1 * 400 µG
Artikel-Nr:
(BOSSBS-4100R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4100R-A488
Lokale Artikelnummer::
BOSSBS-4100R-A488
Beschreibung:
Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptosis during neural tube formation. Required for a normal rate of cytochrome c release and caspase activation during apoptosis; this requirement may depend upon the cell type and the physiological apoptotic cues. Also required for mitochondrial fission during mitosis. Required for formation of endocytic vesicles. Proposed to regulate synaptic vesicle membrane dynamics through association with BCL2L1 isoform Bcl-X(L) which stimulates its GTPase activity in synaptic vesicles; the function may require its recruitment by MFF to clathrin-containing vesicles. Required for programmed necrosis execution. Isoform 1 and isoform 4 inhibit peroxisomal division when overexpressed.
VE:
1 * 100 µl
Artikel-Nr:
(USBI041723-AP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
041723-AP
Lokale Artikelnummer::
USBI041723-AP
Beschreibung:
Anti-SHROOM2 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
VE:
1 * 200 µl
Artikel-Nr:
(USBI039678)
Lieferant:
US Biological
Hersteller-Artikelnummer::
039678
Lokale Artikelnummer::
USBI039678
Beschreibung:
Anti-PARP2 Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-8325R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8325R-FITC
Lokale Artikelnummer::
BOSSBS-8325R-FITC
Beschreibung:
Cell cycle progression is subject to arrest at G1 and G2 checkpoints in response to DNA damage, presumably to allow time for DNA repair prior to entry into S and M phase, respectively. The p53 tumor suppressor is required for one such G1 checkpoint and functions to upregulate expression of GADD 45 and the mitotic inhibitory protein p21. GADD 45 stimulates DNA excision repair in vitro and inhibits entry of cells into S phase, and it apparently acts in concert with GADD 153 in inducing growth arrest. A related DNA-damage inducible gene, GADD 34 synergizes with GADD 45 or GADD 153 in suppressing cell growth. PEG-3 (progression elevated gene-3) shares significant homology with GADD 34 and is inducible by DNA damage. An additional GADD related gene, PA26, is a possible target of p53. Three isoforms of PA26 have been identified as PA26-T1, PA26-T2 and PA26-T3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2675R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2675R-CY5.5
Lokale Artikelnummer::
BOSSBS-2675R-CY5.5
Beschreibung:
a-Fodrin is a universally expressed membrane associated cytoskeletal protein consisting of alpha and beta subunits. The protein is important for maintaining normal membrane structure and supporting cell surface protein function. Alpha Fodrin is one of the important targets cleaved by caspases during apoptosis. The full length 240 kDa protein can be cleaved at several sites within its sequence by activated caspases generating N terminal 150 kDa, C terminal 120 kDa, and 35 kDa major products. Cleavage of alpha Fodrin leads to membrane malfunction and cell shrinkage.
VE:
1 * 100 µl
Artikel-Nr:
(USBII7663-03M)
Lieferant:
US Biological
Hersteller-Artikelnummer::
I7663-03M
Lokale Artikelnummer::
USBII7663-03M
Beschreibung:
Anti-IL1A Mouse Monoclonal Antibody
VE:
1 * 50 µl
Artikel-Nr:
(BOSSBS-4270R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4270R-A680
Lokale Artikelnummer::
BOSSBS-4270R-A680
Beschreibung:
p18 INK4C is a specific inhibitor of cdk4 / cdk6 (it interacts strongly with CDK6 and weakly with CDK4), and is expressed during G1 to S transition in the eukaryotic cell division cycle. It is maximally induced as cells enter S phase. Highest expression levels are found in skeletal muscle, but it is also found in the pancreas and heart.
VE:
1 * 100 µl
Artikel-Nr:
(USBIL1227-60D)
Lieferant:
US Biological
Hersteller-Artikelnummer::
L1227-60D
Lokale Artikelnummer::
USBIL1227-60D
Beschreibung:
Anti-LAMA3 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(USBI042239-PE)
Lieferant:
US Biological
Hersteller-Artikelnummer::
042239-PE
Lokale Artikelnummer::
USBI042239-PE
Beschreibung:
Anti-SPIRE2 Rabbit Polyclonal Antibody (PE (Phycoerythrin))
VE:
1 * 200 µl
Artikel-Nr:
(USBIJ8009-04H)
Lieferant:
US Biological
Hersteller-Artikelnummer::
J8009-04H
Lokale Artikelnummer::
USBIJ8009-04H
Beschreibung:
Anti-Junctional Adhesion Molecule 1 Mouse Monoclonal Antibody [clone: M.Ab.F11]
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-0223R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0223R-HRP
Lokale Artikelnummer::
BOSSBS-0223R-HRP
Beschreibung:
Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11844R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11844R-FITC
Lokale Artikelnummer::
BOSSBS-11844R-FITC
Beschreibung:
GEFT is a 580 amino acid cytoplasmic protein that is highly expressed in excitable tissues such as brain, heart and muscle, and weakly expressed in small intestine, colon, liver, placenta and lung. GEFT may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. GEFT works as a guanine nucleotide exchange factor for the Rho family of small GTPases and links specifically to G alpha q/11-coupled receptors in Rho A activation. GEFT is an important regulator of processes involved in axon and dendrite formation. Involved in skeletal myogenesis, GEFT seems to be an exchange factor primarily for Rac 1 in neurons. Existing as two alternatively spliced variants, GEFT contains a DH (DBL-homology) domain and a PH domain.
VE:
1 * 100 µl
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||
Listenansicht
