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(\\u00B1)-1,2-Pentandiol
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(\\u00B1)-1,2-Pentandiol
Artikel-Nr:
(BOSSBS-13140R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13140R-A647
Lokale Artikelnummer::
BOSSBS-13140R-A647
Beschreibung:
Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromsomal instability (1,2). The FA Group C complementation group gene encodes the protein FANCC, which is located in both cytoplasmic and nuclear compartments. FANCC is expressed in a cell cycle-dependent manner, with the lowest levels at the G1/S boundary and the highest levels in the M-phase. The FANCC protein interacts with other FA complementation group proteins as well as non-FA proteins (3). A human a spectrin II (designated aSpIIs) acts as a scaffold to enhance interactions between FANCC and FANCA to form a nuclear complex (4,5). Another binding partner of FANCC is the BTB/POZ domain containing protein FAZF, which is a transcriptional repressor (6). In hematopoietic cells expressing mutant FANCC, PKR is constitutively phosphorylated and has increased binding affinity for double-stranded RNA (7,8), which suggests that FANCC indirectly suppresses the activity of PKR. These cells are also apoptotic and are hypersensitive to IFNg and TNFa (8). In addition, FANCC protein is involved in the activation of STAT1 through receptors for at least three hematopoietic growth and survival factors (8).
VE:
1 * 100 µl
Artikel-Nr:
(METN30252669)
Lieferant:
Mettler - Toledo
Hersteller-Artikelnummer::
30252669
Lokale Artikelnummer::
METN30252669
Beschreibung:
<p>The G20S extends usability with the same space saving design as the Compact titrators. Supports 150 analysis methods with 12 method functions +12 shortcuts per user, plus LabX Express software. For multiple routine titrations and users.</p>
VE:
1 * 1 ST
Artikel-Nr:
(GRSG600407)
Lieferant:
Greisinger
Hersteller-Artikelnummer::
600407
Lokale Artikelnummer::
GRSG600407
Beschreibung:
This handheld meter with integrated absolute pressure sensor is suitable for measurements in air and non corrosive and non ionizing gases and liquids.
VE:
1 * 1 ST
Lieferant:
APPLICHEM
Beschreibung:
Isoparaffin G analytisches Reagens
Artikel-Nr:
(BOSSBS-9461R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9461R-A488
Lokale Artikelnummer::
BOSSBS-9461R-A488
Beschreibung:
The LIN-12/Notch family of transmembrane receptors plays a central role in development by regulating cell fate and establishing boundaries of gene expression. Notch signaling activates the Hairy/Enhancer of split (HES) genes, which encode basic helix-loop-helix (bHLH) transcriptional repressors that are critical for directing embryonic patterning and development. The Hairy-related transcription factors (HRTs) comprise a subclass of bHLH proteins that exhibit structural similarity with the HES proteins and include HRT1, HRT2 and HRT3. The HRT family (also designated Hesr, Hey, CHF and Gridlock) contain a bHLH domain, an Orange domain and a novel YRPW domain, which is absent in HRT3. The Hairy-related genes map to human chromosomes 8q21, 6q21 and 1p34.3 for HRT1, HRT2 and HRT3, respectively, and are downstream targets for Notch signaling. HRT1 is expressed in the somitic mesoderm, central nervous system, kidney, heart, nasal epithelium and limb buds in murine embryos as well as in adult tissues. It has altered expression in many breast, lung and kidney tumors. Like HRT1, HRT2 and HRT3 are also expressed in developing somites, heart and nervous system.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3730R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3730R
Lokale Artikelnummer::
BOSSBS-3730R
Beschreibung:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. There have been at least 12 different PKC isoforms identified in humans to date including alpha, beta I, beta II, gamma, delta, epsilon, zeta, eta, theta, iota, lambda, and mu. PKC gamma is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3730R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3730R-CY5
Lokale Artikelnummer::
BOSSBS-3730R-CY5
Beschreibung:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. There have been at least 12 different PKC isoforms identified in humans to date including alpha, beta I, beta II, gamma, delta, epsilon, zeta, eta, theta, iota, lambda, and mu. PKC gamma is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3626R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3626R
Lokale Artikelnummer::
BOSSBS-3626R
Beschreibung:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. There have been at least 12 different PKC isoforms identified in humans to date including alpha, beta I, beta II, gamma, delta, epsilon, zeta, eta, theta, iota, lambda, and mu. PKC gamma is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14).
VE:
1 * 100 µl
Lieferant:
VWR Chemicals
Beschreibung:
Abklatschplatten sind ideal zur Überprüfung der mikrobiologischen Kontamination von Oberflächen und Luft (unter Verwendung eines Luftkeimsammlers) in Reinräumen, Isolatoren, RABS (Restricted Access Barrier Systems), in der Lebensmittelindustrie und in Krankenhäusern. Die Dreifachverpackung sorgt dafür, dass die Packung selbst die Umgebung nicht verunreinigt, da die erste Verpackungslage erst direkt vor Betreten des Reinraums entfernt wird. Die Verpackung von Platten mit PCA ist nicht bestrahlt.
Artikel-Nr:
(SIAL33380-100G-F)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
33380-100G-F
Lokale Artikelnummer::
SIAL33380-100G-F
Beschreibung:
3,4-Diaminotoluol, Sigma-Aldrich®
VE:
1 * 100 g
Lieferant:
COMBI-BLOCKS
Beschreibung:
3-Fluorbrenzcatechin
Lieferant:
KOEHLER TECHNISCHE PRODUKTEN
Beschreibung:
Acryl
Lieferant:
BIOLEGEND INC
Beschreibung:
Anti-CD79b (Igbeta) Armenian hamster Monoclonal Antibody [clone: HM79-12] (APC (Allophycocyanin))
Lieferant:
Sigma-Aldrich
Beschreibung:
(R)-(-)-2,2-Dimethyl-1,3-dioxolan-4-ylmethanol, Sigma-Aldrich®
Lieferant:
Bernd Kraft
Beschreibung:
di-Natriumhydrogenphosphat Dodecahydrat, rein
Artikel-Nr:
(USBI125569)
Lieferant:
US Biological
Hersteller-Artikelnummer::
125569
Lokale Artikelnummer::
USBI125569
Beschreibung:
Anti-CYP27A1 Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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