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5-Chloro-1,6-naphthyridine
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5-Chloro-1,6-naphthyridine
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 33-37 kDa, identified as CD20 (Workshop V; Code CD20.12). B9E9 recognizes extracellular domain of CD20. The epitope is similar to or identical to that recognized by other CD20 antibodies including Leu-16 and B1. This MAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood, B cell localization in tissues and B lymphocyte purification by immunosorbent methods. CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. Protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as a calcium channel involved in B-cell activation and cell cycle progression.
Artikel-Nr:
(BOSSBS-11771R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11771R
Lokale Artikelnummer::
BOSSBS-11771R
Beschreibung:
SCA11 is a 1,244 amino acid protein that belongs to the protein kinase superfamily and the CK1 Ser/Thr protein kinase family. The SCA11 gene, comprising of 16 exons, produces a 5.6-kb transcript in which the longest open reading frame is 3,732 nucleotides. Defects in the SCA11 protein are the cause of the disorder spinocerebellar ataxia type 11 (SCA11). Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. The SCA11 disorder is an autosomal dominant cerebellar ataxia (ADCA). It is a relatively benign, late-onset, slowly progressive neurologic disorder. The SCA11 protein has also been implicated in Alzheimer disease and in tangle formation. Existing as three alternatively spliced isoforms, the SCA11 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 15q15.2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13726R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13726R
Lokale Artikelnummer::
BOSSBS-13726R
Beschreibung:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB6 (Protocadherin beta-6) is a 794 amino acid single pass transmembrane protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB6) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. PCDHB6 is likely a calcium-dependent cell adhesion protein that is involved in the maintenance of neural connections in the brain. Unlike most protocadherin-beta proteins, PCDHB6 has not one but two PXXP motifs within its cytoplasmic domain, suggesting a role in signal transduction cascade events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13726R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13726R-CY3
Lokale Artikelnummer::
BOSSBS-13726R-CY3
Beschreibung:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB6 (Protocadherin beta-6) is a 794 amino acid single pass transmembrane protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB6) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. PCDHB6 is likely a calcium-dependent cell adhesion protein that is involved in the maintenance of neural connections in the brain. Unlike most protocadherin-beta proteins, PCDHB6 has not one but two PXXP motifs within its cytoplasmic domain, suggesting a role in signal transduction cascade events.
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR4217-250MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR4217-250MG
Lokale Artikelnummer::
APOSOR4217-250MG
Beschreibung:
3-Chlor-4-(dimethylcarbamoyl)phenylboronsäure 98%
VE:
1 * 250 mg
Artikel-Nr:
(APOSOR9971-5G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR9971-5G
Lokale Artikelnummer::
APOSOR9971-5G
Beschreibung:
3-Chlor-p-kresol 98%
VE:
1 * 5 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Ethyl-4-chlor-5,7-difluorchinolin-3-carboxylat
Lieferant:
Thermo Scientific
Beschreibung:
Chlor(dimethyl)phenylsilan 95%
Lieferant:
Alfa Aesar
Beschreibung:
4-Chlor-m-kresol ≥99%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
4-Chlor-N,N-diisopropylbenzamid
Lieferant:
Alfa Aesar
Beschreibung:
3-Chlor-p-toluidin ≥98%
Lieferant:
Alfa Aesar
Beschreibung:
4-Chlor-2,6-xylenol ≥98%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
3-Chlor-2-fluor-5-(trifluormethyl)benzamid
Lieferant:
GLASWARENFABRIK KARL HECHT
Beschreibung:
Glass plates with plain or frosted surface. Individually wrapped.
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2-Chlor-3,5-dinitro-α,α,α-trifluortoluol 99%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
5-Chlor-2-methoxy-nicotinsäure 98%
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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