6-Chloro-4-methoxypyridazin-3-amine
Artikel-Nr:
(BOSSBS-2173R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2173R-A488
Lokale Artikelnummer::
BOSSBS-2173R-A488
Beschreibung:
The Olfactomedin family comprises a diverse group of secreted glycoproteins, which includes OLFM1 (Noelin-1), OLFM2 (Noelin-2), OLFM3 (Noelin-3), OLFM4 (Noelin-4), tiarin, pancortin, gliomedin and mycocilin. These proteins are implicated in the development of the nervous system. Specifically, OLFM1 and OLFM2 expression is observed in the neural plate and neural crest, as well as in the cranial ganglia in mouse at E8-10, and later in brain tissue and in the zone of polarizing activity in the limb. Overexpression of OLFM1 causes an excess of neural crest emigrations and prolonged neural crest production. OLFM2 participates in the regulation of the development of the anterior nervous system. An Arg144Gln mutation in OLFM2 has been implicated as a possible cause for open-angle glaucoma (OAG).
VE:
1 * 100 µl
Lieferant:
Cytiva
Beschreibung:
Amersham ECL Plex™-Western Blotting Kombinationspackungen bieten ein komplettes System für einen Western Blot mit Fluoreszenz, mit verbesserter Zusammensetzung der Cy3-Konjugate für einen niedrigeren Hintergrund.
Artikel-Nr:
(PRSI25-940)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-940
Lokale Artikelnummer::
PRSI25-940
Beschreibung:
3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta (5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-8187R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8187R-A647
Lokale Artikelnummer::
BOSSBS-8187R-A647
Beschreibung:
The CUB and sushi domain-containing proteins, CSMD1-3, are membrane proteins that are involved in cell-cell adhesion and are weakly expressed in most tissues, with higher levels of expression observed in the cerebellum and hippocampus. CSMD1 is part of the complement system that defends against pathogens through either the classical pathway or the alternative pathway. Located primarily in nerve growth cones, CSMD1 blocks the classical pathway of the immune system and is thought to be involved in tumor suppression, as defects in the gene encoding CSMD1 are associated with squamous cell carcinomas. CSMD2 and CSMD3 are located primarily in the brain and are implicated in some forms of head and neck cancer. Additionally, the CSMD3 gene is a candidate for induction of epileptic seizures.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8187R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8187R-A555
Lokale Artikelnummer::
BOSSBS-8187R-A555
Beschreibung:
The CUB and sushi domain-containing proteins, CSMD1-3, are membrane proteins that are involved in cell-cell adhesion and are weakly expressed in most tissues, with higher levels of expression observed in the cerebellum and hippocampus. CSMD1 is part of the complement system that defends against pathogens through either the classical pathway or the alternative pathway. Located primarily in nerve growth cones, CSMD1 blocks the classical pathway of the immune system and is thought to be involved in tumor suppression, as defects in the gene encoding CSMD1 are associated with squamous cell carcinomas. CSMD2 and CSMD3 are located primarily in the brain and are implicated in some forms of head and neck cancer. Additionally, the CSMD3 gene is a candidate for induction of epileptic seizures.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11690R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11690R-HRP
Lokale Artikelnummer::
BOSSBS-11690R-HRP
Beschreibung:
FIG4 is a 907 amino acid protein that contains one SAC domain through which it is thought to function as a phosphoinositide phosphatase that may play an important role in signal transduction and vesicle trafficking. Defects in the gene encoding FIG4 are the cause of Charcot-Marie-Tooth disease type 4J (CMT4J) and amyotrophic lateral sclerosis type 11 (ALS11), both of which negatively affect the nervous system. CMT4J is a recessive demyelinating disorder of the peripheral nervous system and is characterized by reduced motor nerve conduction velocities and axonal degeneration. Unlike CMT4J, ALS11 is characterized by the degeneration of upper motor neurons in the brain and lower neurons in the spinal cord, causing paralysis and, ultimately, death.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6273R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6273R-HRP
Lokale Artikelnummer::
BOSSBS-6273R-HRP
Beschreibung:
Enolase 1 is a multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.MBP1 binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.Enolase 2 has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.Enolase 3 appears to have a function in striated muscle development and regeneration.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6349R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6349R-CY7
Lokale Artikelnummer::
BOSSBS-6349R-CY7
Beschreibung:
May be involved in the regulation of cell-cell interactions or in synatogenesis during the maturation of the nervous system. NERP peptides are involved in the control of body fluid homeostasis by regulating vasopressin release. Antimicrobial peptide VGF[554-577]: Has bactericidal activity against M. luteus, and antifungal activity against P. Pastoris.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2173R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2173R-CY5
Lokale Artikelnummer::
BOSSBS-2173R-CY5
Beschreibung:
The Olfactomedin family comprises a diverse group of secreted glycoproteins, which includes OLFM1 (Noelin-1), OLFM2 (Noelin-2), OLFM3 (Noelin-3), OLFM4 (Noelin-4), tiarin, pancortin, gliomedin and mycocilin. These proteins are implicated in the development of the nervous system. Specifically, OLFM1 and OLFM2 expression is observed in the neural plate and neural crest, as well as in the cranial ganglia in mouse at E8-10, and later in brain tissue and in the zone of polarizing activity in the limb. Overexpression of OLFM1 causes an excess of neural crest emigrations and prolonged neural crest production. OLFM2 participates in the regulation of the development of the anterior nervous system. An Arg144Gln mutation in OLFM2 has been implicated as a possible cause for open-angle glaucoma (OAG).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11690R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11690R-CY3
Lokale Artikelnummer::
BOSSBS-11690R-CY3
Beschreibung:
FIG4 is a 907 amino acid protein that contains one SAC domain through which it is thought to function as a phosphoinositide phosphatase that may play an important role in signal transduction and vesicle trafficking. Defects in the gene encoding FIG4 are the cause of Charcot-Marie-Tooth disease type 4J (CMT4J) and amyotrophic lateral sclerosis type 11 (ALS11), both of which negatively affect the nervous system. CMT4J is a recessive demyelinating disorder of the peripheral nervous system and is characterized by reduced motor nerve conduction velocities and axonal degeneration. Unlike CMT4J, ALS11 is characterized by the degeneration of upper motor neurons in the brain and lower neurons in the spinal cord, causing paralysis and, ultimately, death.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2173R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2173R-CY5.5
Lokale Artikelnummer::
BOSSBS-2173R-CY5.5
Beschreibung:
The Olfactomedin family comprises a diverse group of secreted glycoproteins, which includes OLFM1 (Noelin-1), OLFM2 (Noelin-2), OLFM3 (Noelin-3), OLFM4 (Noelin-4), tiarin, pancortin, gliomedin and mycocilin. These proteins are implicated in the development of the nervous system. Specifically, OLFM1 and OLFM2 expression is observed in the neural plate and neural crest, as well as in the cranial ganglia in mouse at E8-10, and later in brain tissue and in the zone of polarizing activity in the limb. Overexpression of OLFM1 causes an excess of neural crest emigrations and prolonged neural crest production. OLFM2 participates in the regulation of the development of the anterior nervous system. An Arg144Gln mutation in OLFM2 has been implicated as a possible cause for open-angle glaucoma (OAG).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11807R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11807R-CY5
Lokale Artikelnummer::
BOSSBS-11807R-CY5
Beschreibung:
Aladin (Adracalin) belongs to a family of WD repeat-containing proteins. These proteins have a wide variety of functions, including signal transduction regulation, RNA processing and transcription. Aladin plays a role in peripheral and central nervous system development. It is widely expressed, with the highest expression seen in pituitary gland, corpus callosum, cerebellum, adrenal gland and gastrointestinal structures. Defects in Aladin cause the autosomal recessive disorder achalasia-addisonianism-alacrima (triple A) syndrome. Triple A syndrome is characterized by achalasia, alacrima and adrenocortico-tropin-resistant adrenal insufficiency. Robust expression in neural systems associated with cognitive, motor and sensory functions is consistent with the myriad of symptoms experienced by patients with triple A syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11807R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11807R-A350
Lokale Artikelnummer::
BOSSBS-11807R-A350
Beschreibung:
Aladin (Adracalin) belongs to a family of WD repeat-containing proteins. These proteins have a wide variety of functions, including signal transduction regulation, RNA processing and transcription. Aladin plays a role in peripheral and central nervous system development. It is widely expressed, with the highest expression seen in pituitary gland, corpus callosum, cerebellum, adrenal gland and gastrointestinal structures. Defects in Aladin cause the autosomal recessive disorder achalasia-addisonianism-alacrima (triple A) syndrome. Triple A syndrome is characterized by achalasia, alacrima and adrenocortico-tropin-resistant adrenal insufficiency. Robust expression in neural systems associated with cognitive, motor and sensory functions is consistent with the myriad of symptoms experienced by patients with triple A syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2173R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2173R-A680
Lokale Artikelnummer::
BOSSBS-2173R-A680
Beschreibung:
The Olfactomedin family comprises a diverse group of secreted glycoproteins, which includes OLFM1 (Noelin-1), OLFM2 (Noelin-2), OLFM3 (Noelin-3), OLFM4 (Noelin-4), tiarin, pancortin, gliomedin and mycocilin. These proteins are implicated in the development of the nervous system. Specifically, OLFM1 and OLFM2 expression is observed in the neural plate and neural crest, as well as in the cranial ganglia in mouse at E8-10, and later in brain tissue and in the zone of polarising activity in the limb. Overexpression of OLFM1 causes an excess of neural crest emigrations and prolonged neural crest production. OLFM2 participates in the regulation of the development of the anterior nervous system. An Arg144Gln mutation in OLFM2 has been implicated as a possible cause for open-angle glaucoma (OAG).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6273R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6273R-CY3
Lokale Artikelnummer::
BOSSBS-6273R-CY3
Beschreibung:
Enolase 1 is a multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.MBP1 binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.Enolase 2 has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.Enolase 3 appears to have a function in striated muscle development and regeneration.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI91-886)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-886
Lokale Artikelnummer::
PRSI91-886
Beschreibung:
Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases involved in the development of embryonic nervous and vascular systems. EPHB1 contains two fibronectin type-III domains, one protein kinase domain and one Sterile Alpha Motif (SAM)domain. EPHB1 is able to stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which is also correlated with its association with Grb7, an adaptor molecule implicated in the regulation of cell migration. It binds to Ephrin-B1, Ephrin-B2 and Ephrin-B3. EPHB1 plays an important roles in diverse biological processes including nervous system development, angiogenesis, and neural synapsis formation and maturation and may be involved in cell-cell interactions in the nervous system.
VE:
1 * 50 µG
Preis auf Anfrage
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