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3,5-Difluor-4-methoxybenzonitril
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3,5-Difluor-4-methoxybenzonitril
Lieferant:
SciLabware
Beschreibung:
PYREX®, Borosilikatglas, klar.
Artikel-Nr:
(BOSSBS-9067R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-CY5
Lokale Artikelnummer::
BOSSBS-9067R-CY5
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9067R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-FITC
Lokale Artikelnummer::
BOSSBS-9067R-FITC
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9067R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-A350
Lokale Artikelnummer::
BOSSBS-9067R-A350
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(BIBBCX5/25/SC)
Lieferant:
SciLabware
Hersteller-Artikelnummer::
CX5/25/SC
Lokale Artikelnummer::
BIBBCX5/25/SC
Beschreibung:
PYREX®, borosilicate glass.
VE:
1 * 2 ST
Artikel-Nr:
(662-1665)
Lieferant:
Hanna
Hersteller-Artikelnummer::
HI12301
Lokale Artikelnummer::
HANNHI12301
Beschreibung:
Elektrode, pH, Edge™, HI12301, mit Temperaturfühler und Sensor Check™, pH: 0 - 13, Kunststoff, Membran: Einfach-Keramik, Elektrolyt: Gel, easyPlug 3,5 mm, Für: Mobile Anwendungen
VE:
1 * 1 ST
Lieferant:
SEMADENI
Beschreibung:
HDPE, translucent.
Lieferant:
Sigma-Aldrich
Beschreibung:
5,6,7,8-Tetrahydrochinoxalin, Sigma-Aldrich®
Artikel-Nr:
(FLUO008670-5G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
008670-5G
Lokale Artikelnummer::
FLUO008670-5G
Beschreibung:
1-Chlor-2,4-dibrom-6-fluorbenzol
VE:
1 * 5 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(LAMA101)
Lieferant:
LAMAPLAST
Hersteller-Artikelnummer::
101
Lokale Artikelnummer::
LAMA101
Beschreibung:
LDPE, translucent, narrow mouth
VE:
1 * 1 ST
Artikel-Nr:
(PRTWB0507WHR35)
Lieferant:
Portwest Clothing
Hersteller-Artikelnummer::
B0507WHR35
Lokale Artikelnummer::
PRTWB0507WHR35
Beschreibung:
Anti-static footwear.
VE:
1 * 1 PAAR
Lieferant:
Thermo Scientific
Beschreibung:
2-Brom-6-nitrotoluol
Lieferant:
CHEMPUR
Beschreibung:
4-Fluor-3-nitrobenzonitril
Artikel-Nr:
(REST33049)
Lieferant:
Restek
Hersteller-Artikelnummer::
33049
Lokale Artikelnummer::
REST33049
Beschreibung:
The standard consists of ethanethiol, 1-propanethiol, 1-butanethiol, 1-pentanethiol, 1-hexanethiol, 1-heptanethiol, 3,5-dimethylbenzenethiol, 1-octanethiol, 1-nonanethiol, 1-decanethiol, 1-pentadecanethiolol, 1-hexadecanethiol and 1-octadecanethiol.
VE:
1 * 1 mL
Artikel-Nr:
(BOSSBS-9047R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9047R-A680
Lokale Artikelnummer::
BOSSBS-9047R-A680
Beschreibung:
Voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarisation and plays a central role in taste transduction. Monovalent-specific, non-selective cation channel that mediates the transport of Na(+), K(+) and Cs(+) ions equally well. Activated directly by increases in intracellular Ca(2+), but is impermeable to it. Gating is voltage-dependent and displays rapid activation and deactivation kinetics upon channel stimulation even during sustained elevations in Ca(2+). Also activated by a fast intracellular Ca(2+) increase in response to inositol 1,4,5-triphosphate-producing receptor agonists. The channel is blocked by extracellular acidification. External acidification has 2 effects, a fast reversible block of the current and a slower irreversible enhancement of current inactivation. Is a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. Heat activation is due to a shift of the voltage-dependent activation curve to negative potentials. Activated by arachidonic acid <i>in vitro</i>. May be involved in perception of bitter, sweet and umami tastes. May also be involved in sensing semiochemicals.
VE:
1 * 100 µl
Artikel-Nr:
(FLUO004387-25G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
004387-25G
Lokale Artikelnummer::
FLUO004387-25G
Beschreibung:
1-Chlor-2,6-dibrom-4-fluorbenzol
VE:
1 * 25 g
This is a MarketSource item. Additional charges may apply
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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