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Acetaldehyde+ammonia+trimer
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Acetaldehyde+ammonia+trimer
Artikel-Nr:
(BOSSBS-7647R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7647R-CY5.5
Lokale Artikelnummer::
BOSSBS-7647R-CY5.5
Beschreibung:
Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0276R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0276R-A350
Lokale Artikelnummer::
BOSSBS-0276R-A350
Beschreibung:
Lupus La protein (Sjogren syndrome type B antigen) (SS-B) (La ribonucleoprotein) (La autoantigen) plays a role in the transcription of RNA polymerase III. It is most probably a transcription termination factor. Binds to the 3' termini of virtually all nascent polymerase III transcripts. It is associated with precursor forms of RNA polymerase III transcripts including tRNA and 4.5S, 5S, 7S, and 7-2 RNAs. The phosphorylation sites are at the C-terminal part of the protein. Sera from patients with systemic lupus erythematosus(SLE) often contain that react with the normal cellular La protein as if this antigen was foreign.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5656R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5656R-A680
Lokale Artikelnummer::
BOSSBS-5656R-A680
Beschreibung:
This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Use of alternative polyA sites has been noted for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8870R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8870R-A350
Lokale Artikelnummer::
BOSSBS-8870R-A350
Beschreibung:
The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12477R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12477R-A750
Lokale Artikelnummer::
BOSSBS-12477R-A750
Beschreibung:
The annexin family of calcium-binding proteins is composed of at least ten mammalian genes. It is characterised by a conserved core domain, which binds to phospholipids in a Ca²⁺ dependent manner, and a unique amino terminal region, which may confer binding specificity. The annexin family has been implicated as regulators of such diverse processes as ion-flux, endocytosis and exocytosis, and cellular adhesion. Two forms of Annexin XI, designated A and B, have been identified. Transfection of COS-7 cells with Annexin XI-A, but not Annexin XI-B, causes formation of Annexin XI-associated vesicles.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0315R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0315R-A680
Lokale Artikelnummer::
BOSSBS-0315R-A680
Beschreibung:
FGL2 is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilised by interchain disulfide bonds. It may play a role in physiologic functions at mucosal sites. It is constitutively expressed in cytotoxic T-cells. Lack of expression in other lymphoid- and nonlymphoid-derived cell lines suggested that expression of FGL2 may be restricted to lymphocytes. FGL2 is induced via a mechanism involving IFNG and components of the IFNG signaling pathway, including STAT1 and IRF1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4291R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4291R-FITC
Lokale Artikelnummer::
BOSSBS-4291R-FITC
Beschreibung:
Probable E3 ubiquitin-protein ligase. The BRCA1-BARD1 heterodimer specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Plays a central role in the control of the cell cycle in response to DNA damage. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Also forms a heterodimer with CSTF1/CSTF-50 to modulate mRNA processing and RNAP II stability by inhibiting pre-mRNA 3' cleavage.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11740R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11740R-A750
Lokale Artikelnummer::
BOSSBS-11740R-A750
Beschreibung:
Early B-cell factor 2 is a 575 amino acid protein belonging to the COE family of proteins, whose members are all helix-loop-helix transcription factors. EBF2 is a transcription factor which, in synergy with the Wnt-responsive LEF1/CTNNB1 pathway, activates the decoy receptor for RANKL, OPG, in osteoblasts. OPG, in turn, regulates osteoclast differentiation. Lack of EBF2 has been found to cause a small defect in the terminal differentiation of osteoblasts, along with reduced bone mass and an increase in osteoclasts. localised to the nucleus, EBF2 forms a homodimer or a heterodimer with a related family member.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4527R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4527R-CY5.5
Lokale Artikelnummer::
BOSSBS-4527R-CY5.5
Beschreibung:
Classical swine fever(CSF) is a kind of acute and intense contagious disease in swine, it material damages swine industry. CSF could cause swine appearing disseminated hemorrhage in systemic organ and tissue, degeneration and necrosis in small vascular and capillary endothelial cells. Classical swine fever virus (CSFV) belongs to genera Pestivirus, family Flaviviridae, it’s genome total length is 12.3Kb,including a big ORF, encoding 11 structural and nonstructural proteins.Envelope glycoprotein E2 exists in the form of homodimer; this protein is cleaved from the polyprotein by a cellular signal peptidase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3062R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3062R-HRP
Lokale Artikelnummer::
BOSSBS-3062R-HRP
Beschreibung:
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP alpha, CEBP delta, and CEBP gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL1 response element in the IL6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11632R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11632R-HRP
Lokale Artikelnummer::
BOSSBS-11632R-HRP
Beschreibung:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5643R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5643R-A350
Lokale Artikelnummer::
BOSSBS-5643R-A350
Beschreibung:
This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Use of alternative polyA sites has been noted for this gene. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7647R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7647R-CY3
Lokale Artikelnummer::
BOSSBS-7647R-CY3
Beschreibung:
Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10157R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10157R-A647
Lokale Artikelnummer::
BOSSBS-10157R-A647
Beschreibung:
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11887R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11887R-FITC
Lokale Artikelnummer::
BOSSBS-11887R-FITC
Beschreibung:
Two highly conserved complexes are responsible for the assembly of tight junctions, the Crumbs-Pals1-Patj complex and the Cdc42-Par6-Par3-aPKC complex. Tight junctions assist in the formation of polarity in the epithelia by establishing a barrier to separate apical and basolateral membranes. Pals1, importantly, mediates interaction between the two complexes via interaction with Par6. Loss of Pals1 function results in delayed polarization, decreased transepithelial electrical resistance and an inability to form lumenal cysts. Because tumors exhibit perturbations in epithelial polarity, Pals1 presents a new potential target in the study of carcinogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13122R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13122R-A750
Lokale Artikelnummer::
BOSSBS-13122R-A750
Beschreibung:
The exosome is a multisubunit complex of 3? to 5? exoribonucleases. It is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich elements in their untranslated 3? region. EXOSC7 (exosome component 7), also known as p8, EAP1, RRP42 (Ribosomal RNA-processing protein 42), Rrp42p or hRrp42p, is a component of the exosome multienzyme ribonuclease complex. It belongs to the RNase PH family and localizes to the nucleolus. EXOSC7 is one of the six RNase-PH domain subunits of the exosome. Together, these six subunits form a PNPase-like ring. EXOSC7 is required for the processing of the 7S pre-RNA.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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