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[(tert-Butoxycarbonyl)aminooxy]acetic+acid


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Artikel-Nr: (COBBHC-3349-1G)

Lieferant:  COMBI-BLOCKS
Hersteller-Artikelnummer:: HC-3349-1G
Lokale Artikelnummer:: COBBHC-3349-1G
Beschreibung:   4-(1,3-Oxazol-2-yl)anilin Hydrochlorid
VE:  1 * 1 g
Market Source Item This is a MarketSource item. Additional charges may apply
Artikel-Nr: (BOSSBS-2734R-CY5)

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-2734R-CY5
Lokale Artikelnummer:: BOSSBS-2734R-CY5
Beschreibung:   Transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. Forms complexes with different corepressors and histone deacetylases to repress the transcriptional expression of different subsets of target genes. Represses its target genes by binding directly to the DNA sequence 5'-TTCCTAGAA-3' (BCL6-binding site) or indirectly by repressing the transcriptional activity of transcription factors. In GC B-cells, represses genes that function in differentiation, inflammation, apoptosis and cell cycle control, also autoregulates its transcriptional expression and up-regulates, indirectly, the expression of some genes important for GC reactions, such as AICDA, through the repression of microRNAs expression, like miR155. An important function is to allow GC B-cells to proliferate very rapidly in response to T-cell dependent antigens and tolerate the physiological DNA breaks required for immunglobulin class switch recombination and somatic hypermutation without inducing a p53/TP53-dependent apoptotic response. In follicular helper CD4(+) T-cells (T(FH) cells), promotes the expression of T(FH)-related genes but inhibits the differentiation of T(H)1, T(H)2 and T(H)17 cells. Also required for the establishment and maintenance of immunological memory for both T- and B-cells. Suppresses macrophage proliferation through competition with STAT5 for STAT-binding motifs binding on certain target genes, such as CCL2 and CCND2. In response to genotoxic stress, controls cell cycle arrest in GC B-cells in both p53/TP53-dependedent and -independent manners. Besides, also controls neurogenesis through the alteration of the composition of NOTCH-dependent transcriptional complexes at selective NOTCH targets, such as HES5, including the recruitment of the deacetylase SIRT1 and resulting in an epigenetic silencing leading to neuronal differentiation.
VE:  1 * 100 µl
Lieferant:  COMBI-BLOCKS
Beschreibung:   4-((Trifluormethyl)thio)benzoesäure
Lieferant:  Serva
Beschreibung:   Vancomycin Hydrochlorid

Lieferant:  COMBI-BLOCKS
Hersteller-Artikelnummer:: HC-6003-5G
Lokale Artikelnummer:: COBBHC-6003-5G
Beschreibung:   6-Chlorimidazo[1,2-b]pyridazin Hydrochlorid
VE:  1 * 5 g
Market Source Item This is a MarketSource item. Additional charges may apply
Lieferant:  COMBI-BLOCKS
Beschreibung:   5-Methylimidazo[1,2-a]pyridin Hydrochlorid
Lieferant:  COMBI-BLOCKS
Beschreibung:   6-Chlorimidazo[1,2-a]pyridin Hydrochlorid
Lieferant:  Thermo Scientific
Beschreibung:   4-Formylphenylboronsäure
Lieferant:  MENAI
Beschreibung:   1-(3,5-Bis(trifluormethyl)phenyl)thioharnstoff
Lieferant:  COMBI-BLOCKS
Beschreibung:   3,4-Dichlor-2-methylphenylboronsäure
Lieferant:  Sigma-Aldrich
Beschreibung:   Irreversible inhibitor of serine proteases with lysine or arginine substrate specificities.
Lieferant:  PanReac AppliChem
Beschreibung:   Vancomycin Hydrochlorid

Lieferant:  Molekula
Hersteller-Artikelnummer:: 16589050-1G
Lokale Artikelnummer:: MOLE16589050-1G
Beschreibung:   TCEP-HCl (Tris(2-carboxyethyl)phosphin Hydrochlorid)
VE:  1 * 1 g
Market Source Item This is a MarketSource item. Additional charges may apply

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 25-534
Lokale Artikelnummer:: PRSI25-534
Beschreibung:   HOXB8 is a member of the Antp homeobox family and is a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. HOXB8 functions as a sequence-specific transcription factor that is involved in development. Increased expression of this HOXB8 gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.
VE:  1 * 50 µG
Lieferant:  COMBI-BLOCKS
Beschreibung:   2-Brom-N-methyl-5-(trifluormethoxy)anilin Hydrochlorid
Lieferant:  COMBI-BLOCKS
Beschreibung:   5-(1-Chlor-2-methylpropan-2-yl)-3-(3-nitrophenyl)-1,2,4-oxadiazol
Preis auf Anfrage
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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