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3,5-Diiodsalicyls\\\\u00E4ure
Artikel-Nr:
(PRSI27-654)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-654
Lokale Artikelnummer::
PRSI27-654
Beschreibung:
HOXB9 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. HOXB9 is one of several homeobox HOXB genes located in a cluster on chromosome 17. The exact role of this gene has yet to be determined.
VE:
1 * 50 µG
Lieferant:
Sigma-Aldrich
Beschreibung:
2-Chlorethylammoniumchlorid, Sigma-Aldrich®
Artikel-Nr:
(SIAL176885-25G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
176885-25G
Lokale Artikelnummer::
SIAL176885-25G
Beschreibung:
Benzhydrylammoniumchlorid, Sigma-Aldrich®
VE:
1 * 25 g
Lieferant:
COMBI-BLOCKS
Beschreibung:
4-Bromphenylhydraziniumchlorid
Lieferant:
Spectrum Chemical
Beschreibung:
Form: Granular
Use: excipient, biochemistry.
Lieferant:
Thermo Scientific
Beschreibung:
Cysteaminiumchlorid
Artikel-Nr:
(BOSSBS-2734R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2734R-CY5.5
Lokale Artikelnummer::
BOSSBS-2734R-CY5.5
Beschreibung:
Transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. Forms complexes with different corepressors and histone deacetylases to repress the transcriptional expression of different subsets of target genes. Represses its target genes by binding directly to the DNA sequence 5'-TTCCTAGAA-3' (BCL6-binding site) or indirectly by repressing the transcriptional activity of transcription factors. In GC B-cells, represses genes that function in differentiation, inflammation, apoptosis and cell cycle control, also autoregulates its transcriptional expression and up-regulates, indirectly, the expression of some genes important for GC reactions, such as AICDA, through the repression of microRNAs expression, like miR155. An important function is to allow GC B-cells to proliferate very rapidly in response to T-cell dependent antigens and tolerate the physiological DNA breaks required for immunglobulin class switch recombination and somatic hypermutation without inducing a p53/TP53-dependent apoptotic response. In follicular helper CD4(+) T-cells (T(FH) cells), promotes the expression of T(FH)-related genes but inhibits the differentiation of T(H)1, T(H)2 and T(H)17 cells. Also required for the establishment and maintenance of immunological memory for both T- and B-cells. Suppresses macrophage proliferation through competition with STAT5 for STAT-binding motifs binding on certain target genes, such as CCL2 and CCND2. In response to genotoxic stress, controls cell cycle arrest in GC B-cells in both p53/TP53-dependedent and -independent manners. Besides, also controls neurogenesis through the alteration of the composition of NOTCH-dependent transcriptional complexes at selective NOTCH targets, such as HES5, including the recruitment of the deacetylase SIRT1 and resulting in an epigenetic silencing leading to neuronal differentiation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2734R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2734R-HRP
Lokale Artikelnummer::
BOSSBS-2734R-HRP
Beschreibung:
Transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. Forms complexes with different corepressors and histone deacetylases to repress the transcriptional expression of different subsets of target genes. Represses its target genes by binding directly to the DNA sequence 5'-TTCCTAGAA-3' (BCL6-binding site) or indirectly by repressing the transcriptional activity of transcription factors. In GC B-cells, represses genes that function in differentiation, inflammation, apoptosis and cell cycle control, also autoregulates its transcriptional expression and up-regulates, indirectly, the expression of some genes important for GC reactions, such as AICDA, through the repression of microRNAs expression, like miR155. An important function is to allow GC B-cells to proliferate very rapidly in response to T-cell dependent antigens and tolerate the physiological DNA breaks required for immunglobulin class switch recombination and somatic hypermutation without inducing a p53/TP53-dependent apoptotic response. In follicular helper CD4(+) T-cells (T(FH) cells), promotes the expression of T(FH)-related genes but inhibits the differentiation of T(H)1, T(H)2 and T(H)17 cells. Also required for the establishment and maintenance of immunological memory for both T- and B-cells. Suppresses macrophage proliferation through competition with STAT5 for STAT-binding motifs binding on certain target genes, such as CCL2 and CCND2. In response to genotoxic stress, controls cell cycle arrest in GC B-cells in both p53/TP53-dependedent and -independent manners. Besides, also controls neurogenesis through the alteration of the composition of NOTCH-dependent transcriptional complexes at selective NOTCH targets, such as HES5, including the recruitment of the deacetylase SIRT1 and resulting in an epigenetic silencing leading to neuronal differentiation.
VE:
1 * 100 µl
Lieferant:
MP Biomedicals
Beschreibung:
Storage: Store at room temperature (15-30 °C)
L-Lysine monohydrochloride is widely used as nutritional supplements in food and beverage industries. It can also be used in animal feed as source of L-Lysine. L-Lysine Monohydrochloride can be used in a wide variety of industries including: food production, beverage, pharmaceutical, agriculture/animal feed, and various other industries. L-Lysine monohydrochloride is a key amino acid in calcium absorption.
Artikel-Nr:
(BOSSBS-1380R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1380R-A750
Lokale Artikelnummer::
BOSSBS-1380R-A750
Beschreibung:
G-protein coupled estrogen receptor that binds to 17-beta-estradiol (E2) with high affinity, leading to rapid and transient activation of numerous intracellular signaling pathways. Stimulates cAMP production, calcium mobilisation and tyrosine kinase Src inducing the release of heparin-bound epidermal growth factor (HB-EGF) and subsequent transactivation of the epidermal growth factor receptor (EGFR), activating downstream signaling pathways such as PI3K/Akt and ERK/MAPK. Mediates pleiotropic functions among others in the cardiovascular, endocrine, reproductive, immune and central nervous systems. Has a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a RAMP3-dependent manner. Regulates arterial blood pressure by stimulating vasodilation and reducing vascular smooth muscle and microvascular endothelial cell proliferation. Plays a role in blood glucose homeostasis contributing to the insulin secretion response by pancreatic beta cells. Triggers mitochondrial apoptosis during pachytene spermatocyte differentiation. Stimulates uterine epithelial cell proliferation. Enhances uterine contractility in response to oxytocin. Contributes to thymic atrophy by inducing apoptosis. Attenuates TNF-mediated endothelial expression of leukocyte adhesion molecules. Promotes neuritogenesis in developing hippocampal neurons. Plays a role in acute neuroprotection against NMDA-induced excitotoxic neuronal death. Increases firing activity and intracellular calcium oscillations in luteinizing hormone-releasing hormone (LHRH) neurons. Inhibits early osteoblast proliferation at growth plate during skeletal development. Inhibits mature adipocyte differentiation and lipid accumulation. Involved in the recruitment of beta-arrestin 2 ARRB2 at the plasma membrane in epithelial cells.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
3,4-Dimethylphenylhydraziniumchlorid
Artikel-Nr:
(UPCHA-702)
Lieferant:
UPCHURCH SCIENTIFIC
Hersteller-Artikelnummer::
A-702
Lokale Artikelnummer::
UPCHA-702
Beschreibung:
Außerordentlich einheitliche Porosität, die eine längere Filtration und konsistentes Hubvolumen von Fritte zu Fritte gewährleistet. Diese Fritten sind biokompatibel und inert gegenüber den meisten Lösungsmitteln, sodass sie sich gut für bioanalytische Anwendungen eignen. Die Scheibenringe aus PCTFE sind ein wenig dicker als die Frittenscheibe und bieten eine verbesserte Abdichtung und ausgezeichnete Chemikalienbeständigkeit.
VE:
1 * 1 ST
Artikel-Nr:
(MOLEM62132853)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M62132853
Lokale Artikelnummer::
MOLEM62132853
Beschreibung:
2-Fluorphenylhydraziniumchlorid
VE:
1 * 5 g
 This is a MarketSource item. Additional charges may apply
Lieferant:
Sigma-Aldrich
Beschreibung:
DL-Lysin Monohydrochlorid, Sigma-Aldrich®
Lieferant:
Thermo Scientific
Beschreibung:
2-Chlorphenylhydraziniumchlorid
Lieferant:
FLUOROCHEM
Beschreibung:
4-Fluorphenylhydraziniumchlorid
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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