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5-Fluoro-4-iodopyridin-2-amine
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5-Fluoro-4-iodopyridin-2-amine
Artikel-Nr:
(BOSSBS-11773R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11773R-A750
Lokale Artikelnummer::
BOSSBS-11773R-A750
Beschreibung:
Terminally differentiating mammalian epidermal cells acquire an insoluble, 10 to 20 nm thick protein deposit on the intracellular surface of the plasma membrane, known as the cross-linked cell envelope (CE). The CE is a component of the epidermis that is generated through the formation of disulfide bonds and gamma-glutamyl-lysine isodipeptide bonds, which are formed by the action of transglutaminases (TGases). TGases are Ca2+-dependent enzymes, which catalyse the formation of isopeptide bonds by transferring an amine to a glutaminyl residue, thereby cross-linking glutamine residues and lysine residues in substrate proteins. TGases influence numerous biological processes, including blood coagulation, epidermal differentiation, seminal fluid coagulation, fertilisation, cell differentiation and apoptosis. TGase6 (transglutaminase 6), also known as TGM6, TGY or TGM3L, is a 706 amino acid protein that catalyses the cross-linking of proteins and the conjugation of proteins to polyamines. As a result of alternative splicing, two TGase6 isoforms exist.
VE:
1 * 100 µl
Artikel-Nr:
(MOLE85430679-5G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
85430679-5G
Lokale Artikelnummer::
MOLE85430679-5G
Beschreibung:
Adenin Hydrochlorid
VE:
1 * 5 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-4176R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4176R
Lokale Artikelnummer::
BOSSBS-4176R
Beschreibung:
Functions as a polyspecific organic cation transporter, efficiently transporting many organic cations such as monoamine neurotransmitters 1-methyl-4-phenylpyridinium and biogenic amines including serotonin, dopamine, norepinephrine and epinephrine. May play a role in regulating central nervous system homeostasis of monoamine neurotransmitters. May be involved in luminal transport of organic cations in the kidney and seems to use luminal proton gradient to drive organic cation reabsorption. Does not seem to transport nucleoside and nucleoside analogs such as uridine, cytidine, thymidine, adenosine, inosine, guanosine, and azidothymidine. In (PubMed:16873718) adenosine is efficiently transported but in a fashion highly sensitive to extracellular pH, with maximal activity in the pH range 5.5 to 6.5. Glu-206 is essential for the cation selectivity and may function as the charge sensor for cationic substrates. Transport is chloride and sodium-independent but appears to be sensitive to changes in membrane potential. Weakly inhibited by the classical inhibitors of equilibrative nucleoside transport, dipyridamole, dilazep, and nitrobenzylthioinosine. May play a role in the regulation of extracellular adenosine concentrations in cardiac tissues, in particular during ischemia.
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
N,N-Dimethyloctylamin, Sigma-Aldrich®
Lieferant:
Thermo Scientific
Beschreibung:
The methyl-PEG<sub>n</sub>-amine (MA[PEG]<sub>n</sub>) PEGylation reagents are methyl ether-terminated PEG amines that are used for modifying proteins or surfaces such as beads, nanoparticles and self-assembled monolayers. These PEGylation reagents are homogenous compounds of defined molecular weight and spacer length, providing precision in optimising modification applications.
Lieferant:
Spectrum Chemical
Beschreibung:
Adenine hydrochloride
Artikel-Nr:
(BOSSBS-4176R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4176R-HRP
Lokale Artikelnummer::
BOSSBS-4176R-HRP
Beschreibung:
Functions as a polyspecific organic cation transporter, efficiently transporting many organic cations such as monoamine neurotransmitters 1-methyl-4-phenylpyridinium and biogenic amines including serotonin, dopamine, norepinephrine and epinephrine. May play a role in regulating central nervous system homeostasis of monoamine neurotransmitters. May be involved in luminal transport of organic cations in the kidney and seems to use luminal proton gradient to drive organic cation reabsorption. Does not seem to transport nucleoside and nucleoside analogs such as uridine, cytidine, thymidine, adenosine, inosine, guanosine, and azidothymidine. In (PubMed:16873718) adenosine is efficiently transported but in a fashion highly sensitive to extracellular pH, with maximal activity in the pH range 5.5 to 6.5. Glu-206 is essential for the cation selectivity and may function as the charge sensor for cationic substrates. Transport is chloride and sodium-independent but appears to be sensitive to changes in membrane potential. Weakly inhibited by the classical inhibitors of equilibrative nucleoside transport, dipyridamole, dilazep, and nitrobenzylthioinosine. May play a role in the regulation of extracellular adenosine concentrations in cardiac tissues, in particular during ischemia.
VE:
1 * 100 µl
Artikel-Nr:
(ACRO156000250)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
156000250
Lokale Artikelnummer::
ACRO156000250
Beschreibung:
Appearance: Light yellow to light brown Crystalline powder
VE:
1 * 25 g
Lieferant:
Sigma-Aldrich
Beschreibung:
Adenin Hydrochlorid, Sigma-Aldrich®
Artikel-Nr:
(MOLE30459654-5G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
30459654-5G
Lokale Artikelnummer::
MOLE30459654-5G
Beschreibung:
(±)-1-Aminoindan
VE:
1 * 5 g
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-12460R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12460R
Lokale Artikelnummer::
BOSSBS-12460R
Beschreibung:
Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during the detoxification of alcohol-derived acetaldehyde; metabolism of corticosteroids, biogenic amines and neurotransmitters; and lipid peroxidation. ALDH1A1, also designated retinal dehydrogenase 1 (RalDH1 or RALDH1), aldehyde dehydrogenase family 1 member A1, aldehyde dehydrogenase cytosolic, ALDHII, ALDH-E1 or ALDH E1, is a retinal dehydrogenase that participates in the biosynthesis of retinoic acid (RA). There are two major liver isoforms of ALDH1 that can localize to cytosolic or mitochondrial space. The ALDH1A2 (RALDH2, RALDH2-T) gene produces three different transcripts and also catalyzes the synthesis of RA from retinaldehyde. ALDH1A3 (ALDH6, RALDH3, ALDH1A6) is a 37 kb gene that consists of 13 exons and produces a major transcript of approximately 3.5 kb most abundant in salivary gland, stomach and kidney. ALDH3A1 (stomach type, ALDH3, ALDHIII) forms a cytoplasmic homodimer that preferentially oxidizes aromatic aldehyde substrates. ALDH genes upregulate as a part of the oxidative stress response, and appear to be abundant in certain tumors that have an accelerated metabolism toward chemotherapy agents.
VE:
1 * 100 µl
Artikel-Nr:
(ABNOPAB16034)
Lieferant:
Abnova
Hersteller-Artikelnummer::
PAB16034
Lokale Artikelnummer::
ABNOPAB16034
Beschreibung:
Rabbit polyclonal antibody raised against synthetic peptide of biogenic amine (5HT) receptor.
VE:
1 * 100 µG
Artikel-Nr:
(USBI031934-BIOTIN)
Lieferant:
US Biological
Hersteller-Artikelnummer::
031934-BIOTIN
Lokale Artikelnummer::
USBI031934-BIOTIN
Beschreibung:
Anti-KDM1B Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 200 µl
Artikel-Nr:
(MOLEM86123311)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M86123311
Lokale Artikelnummer::
MOLEM86123311
Beschreibung:
N-Methylethylamin
VE:
1 * 25 g
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(USBI129234)
Lieferant:
US Biological
Hersteller-Artikelnummer::
129234
Lokale Artikelnummer::
USBI129234
Beschreibung:
Anti-KDM1A Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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