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5-Bromothiophen-2-amine,+N-BOC+protected
Artikel-Nr:
(ICNA04808274)
Lieferant:
MP Biomedicals
Hersteller-Artikelnummer::
04808274
Lokale Artikelnummer::
ICNA04808274
Beschreibung:
Brilliant blue G is a useful dye for SDS gels as it readily stains proteins with minimal background color. Protein bands can be visualised during staining. It has been used in the Bradford dye-binding protein assay.
VE:
1 * 10 g
Artikel-Nr:
(786-497)
Lieferant:
G-Biosciences
Hersteller-Artikelnummer::
786-497
Lokale Artikelnummer::
GENO786-497
Beschreibung:
G-Biosciences' Coomassie Brilliant Blue (CBB) G-250 and R-250 Stain are based on a colloidal Coomassie stain. CBB G-250 and R-250 stain proteins with high band visibility. The staining of gels with CBB G-250 and R-250 allows the examination of protein bands even during the staining process.
VE:
1 * 1 L
Artikel-Nr:
(MANA701440.101)
Lieferant:
MACHEREY-NAGEL
Hersteller-Artikelnummer::
701440.101
Lokale Artikelnummer::
MANA701440.101
Beschreibung:
MBDSTFA is a silylation reagent that donates a tert-butyldimethylsilyl group (TBDMS) for derivatizing active hydrogen atoms in hydroxyl, carboxyl and thiol groups, primary and secondary amines as well as amino acids. Fast reactions (typically 5–20 min) with high yields (> 96 %). By-products are neutral and volatile.
VE:
1 * 1 KIT
Lieferant:
Thermo Scientific
Beschreibung:
Thermo Scientific Pierce coomassie brilliant blue dyes are composed of one of the most common forms of coomassie dye, which is a key component of various colorimetric protein gel stains. Coomassie R-250 and G-250 dyes are two chemical forms of a disulphonated triphenylmethane compound that is commonly used as the basis of stains for detection of proteins in gel electrophoresis and bradford-type assay reagents for protein quantitation. The R-250 (red-tinted) form lacks two methyl groups that are present in the G-250 (green-tinted) form, which is also called colloidal coomassie dye.
Artikel-Nr:
(HONE65709.2500)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
65709.2500
Lokale Artikelnummer::
HONE65709.2500
Beschreibung:
Acetonitril
VE:
1 * 2,5 L
Lieferant:
MP Biomedicals
Beschreibung:
Coomassie® Brilliant Blue R-250 is a fast acting, sensitive dye, which can be used on SDS gels, IEF gels, and standard gels.
Artikel-Nr:
(PRSIXPS-2020)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XPS-2020
Lokale Artikelnummer::
PRSIXPS-2020
Beschreibung:
The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s disease, epilepsy and ischemic neuronal cell death. Increased membrane surface expression of the NR1 subunit of the receptor has been associated with synaptic plasticity. There are a number of different splice variants of the NR1. Differential splicing of three exons in the NR1 subunit generates up to eight NR1 splice variants and 7 of these have been identified in cDNA libraries. These exons encode a 21 amino acid N-terminal domain (N1) and adjacent sequences in the C-terminus (C1 and C2). Splicing out the C2 cassette eliminates the first stop codon and produces a new reading frame that generates a new sequence of 22 amino acids (C2'). Considerable attention has been focused on the distribution and expression of these splice variants that may affect the functional properties and regulation of the NMDAR.
VE:
1 * 25 µG
Artikel-Nr:
(PRSIXPS-2021)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XPS-2021
Lokale Artikelnummer::
PRSIXPS-2021
Beschreibung:
The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s disease, epilepsy and ischemic neuronal cell death. Increased membrane surface expression of the NR1 subunit of the receptor has been associated with synaptic plasticity. There are a number of different splice variants of the NR1. Differential splicing of three exons in the NR1 subunit generates up to eight NR1 splice variants and 7 of these have been identified in cDNA libraries. These exons encode a 21 amino acid N-terminal domain (N1) and adjacent sequences in the C-terminus (C1 and C2). Splicing out the C2 cassette eliminates the first stop codon and produces a new reading frame that generates a new sequence of 22 amino acids (C2'). Considerable attention has been focused on the distribution and expression of these splice variants that may affect the functional properties and regulation of the NMDAR.
VE:
1 * 25 µG
Artikel-Nr:
(PRSIXPS-2022)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XPS-2022
Lokale Artikelnummer::
PRSIXPS-2022
Beschreibung:
The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s disease, epilepsy and ischemic neuronal cell death. Increased membrane surface expression of the NR1 subunit of the receptor has been associated with synaptic plasticity. There are a number of different splice variants of the NR1. Differential splicing of three exons in the NR1 subunit generates up to eight NR1 splice variants and 7 of these have been identified in cDNA libraries. These exons encode a 21 amino acid N-terminal domain (N1) and adjacent sequences in the C-terminus (C1 and C2). Splicing out the C2 cassette eliminates the first stop codon and produces a new reading frame that generates a new sequence of 22 amino acids (C2'). Considerable attention has been focused on the distribution and expression of these splice variants that may affect the functional properties and regulation of the NMDAR.
VE:
1 * 25 µG
Lieferant:
MP Biomedicals
Beschreibung:
Storage: -20 °C.
Adenosine 5'-triphosphate (ATP) and its phosphate bonds are the basic components of energy exchange in many biological systems. Adenosine 5'-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is used in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger cAMP. ATP provides the metabolic energy to drive metabolic pumps. ATP serves as a coenzyme in a wide array of enzymatic reactions. P2 purinergic agonist; increases activity of Ca2+-activated K+ channels; substrate for ATP-dependent enzyme systems.
Artikel-Nr:
(786-498)
Lieferant:
G-Biosciences
Hersteller-Artikelnummer::
786-498
Lokale Artikelnummer::
GENO786-498
Beschreibung:
G-Biosciences' Coomassie Brilliant Blue (CBB) G-250 and R-250 Stain are based on a colloidal Coomassie stain. CBB G-250 and R-250 stain proteins with high band visibility. The staining of gels with CBB G-250 and R-250 allows the examination of protein bands even during the staining process.
VE:
1 * 1 L
Lieferant:
MP Biomedicals
Beschreibung:
Methotrexate is a cell cycle arresting agent with varying effects. Methotrexate has been reported to arrest the cell cycle in late G1/S thus leading to the inhibition of the synthesis of DNA, RNA, thymidylates, and proteins. The main mechanism of action is reported to involve the inhibition of enzymes involved in purine metabolism which leads to the accumulation of adenosine or the suppression of intercellular adhesion molecule expression by T cells. Additionally, this compound has been observed to inhibit DHFR.
Methotrexate is used for chemotherapy either alone or in combination with other agents. It is effective for the treatment of a number of cancers including: breast, head and neck, leukemia, lymphoma, lung, osteosarcoma, bladder, and trophoblastic neoplasms. It is also used in treatment of autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It is used to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites. Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also shows immunosuppressive effects in, e.g., rheumatoid arthritis. Methotrexate is an allosteric inhibititor of dihydrofolate reductase (DHFR), the enzyme that catalyzes the conversion of dihydrofolate to tetrahydrofolate. Since tetrahydrolfolate is required for purine and pyrimidine synthesis, methotrexate treatment results in the inhibition of DNA and RNA synthesis.
Artikel-Nr:
(PRSI5437)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5437
Lokale Artikelnummer::
PRSI5437
Beschreibung:
GAS Antibody: Steroid receptor co-activators (SRCs) were initially described as nuclear receptor transcription co-activators, but they have recently been determined to co-regulate transcription initiated by other transcription factors. GAS is a recently identified glutamate-rich protein that interacts with SRC1, but not GRIP1 or AIB1, the other two members of the SRC family. GAS can also interact with the alpha subunit of the estrogen receptor (ERalpha), but not other receptors such as the retinoic acid receptor a, suggesting the interaction between GAS and ERalpha is relatively specific. Depletion of GAS by RNA interference in MCF7 cells led to a decrease in the mRNA and protein levels of ER target genes such as pS2, c-Myc and cyclin D1, indicating the role of GAS in the regulation of ER target genes. GAS has also been found to associate with an SET1-like methyltransferase complex specific for H3K4 methylation, suggesting that GAS has multiple roles in transcriptional regulation.
VE:
1 * 100 µG
Artikel-Nr:
(786-495)
Lieferant:
G-Biosciences
Hersteller-Artikelnummer::
786-495
Lokale Artikelnummer::
GENO786-495
Beschreibung:
G-Biosciences' Coomassie Brilliant Blue (CBB) G-250 and R-250 Stain are based on a colloidal Coomassie stain. CBB G-250 and R-250 stain proteins with high band visibility. The staining of gels with CBB G-250 and R-250 allows the examination of protein bands even during the staining process.
VE:
1 * 10 g
Artikel-Nr:
(121-0039)
Lieferant:
NPS
Hersteller-Artikelnummer::
570010
Lokale Artikelnummer::
NPSD570010
Beschreibung:
Simultanteststreifen zur Risikoabschätzung auf Säuren/Laugen, Fluoride, Petroleumprodukte/organische Lösungsmittel, Chlor/Brom/Iod und feuergefährliche Substanzen.
VE:
1 * 10 ST
Artikel-Nr:
(PIER22360)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
22360
Lokale Artikelnummer::
PIER22360
Beschreibung:
Thermo Scientific Pierce SMCC is a hetero-bifunctional crosslinker that contain N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at pH 7–9 to form amide bonds, while maleimides react with sulfhydryl groups at pH 6.5–7.5 to form stable thioether bonds. In aqueous solutions, NHS ester hydrolytic degradation is a competing reaction whose rate increases with pH. The maleimide group is more stable than the NHS-ester group, but will slowly hydrolyze and lose its reaction specificity for sulfhydryls at pH values > 7.5. For these reasons, conjugations with these crosslinkers are usually performed at pH 7.2–7.5, with the NHS ester (amine-targeted) reacted before or simultaneous with the maleimide (sulfhydryl-targeted) reaction.
VE:
1 * 50 mg
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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