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Essigs\\u00E4ure-[D1]
Artikel-Nr:
(BOSSBS-0193R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0193R-CY7
Lokale Artikelnummer::
BOSSBS-0193R-CY7
Beschreibung:
Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. However, NTF3 only supports axonal extension through NTRK1 but has no effect on neuron survival. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades driving cell survival and differentiation. Through SHC1 and FRS2 activates a GRB2-Ras-MAPK cascade that regulates cell differentiation and survival. Through PLCG1 controls NF-Kappa-B activation and the transcription of genes involved in cell survival. Through SHC1 and SH2B1 controls a Ras-PI3 kinase-AKT1 signaling cascade that is also regulating survival. In absence of ligand and activation, may promote cell death, making the survival of neurons dependent on trophic factors. Isoform TrkA-III is resistant to NGF, constitutively activates AKT1 and NF-kappa-B and is unable to activate the Ras-MAPK signaling cascade. Antagonizes the anti-proliferative NGF-NTRK1 signaling that promotes neuronal precursors differentiation. Isoform TrkA-III promotes angiogenesis and has oncogenic activity when overexpressed.
VE:
1 * 100 µl
Artikel-Nr:
(ABCRAB106364.0005)
Lieferant:
ABCR
Hersteller-Artikelnummer::
AB106364.0005
Lokale Artikelnummer::
ABCRAB106364.0005
Beschreibung:
Tris(2,2,6,6-tetramethyl-3,5-heptandionato-O,O')yttrium(III)
VE:
1 * 5 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-12262R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12262R-A750
Lokale Artikelnummer::
BOSSBS-12262R-A750
Beschreibung:
The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.
VE:
1 * 100 µl
Artikel-Nr:
(SIAL524514-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
524514-5G
Lokale Artikelnummer::
SIAL524514-5G
Beschreibung:
Tris[N,N-bis(trimethylsilyl)amid]yttrium(III), Sigma-Aldrich®
VE:
1 * 5 g
Artikel-Nr:
(BOSSBS-8498R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8498R-A488
Lokale Artikelnummer::
BOSSBS-8498R-A488
Beschreibung:
REG1 beta is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV based on the primary structures of the encoded proteins. REG1 beta highly similar to the REG1 alpha protein. The related REG1 alpha protein is associated with islet cell regeneration and diabetogenesis, and may be involved in pancreatic lithogenesis. Reg family members REG1 alpha, REGL, PAP and this gene are tandomly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9054R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9054R-A647
Lokale Artikelnummer::
BOSSBS-9054R-A647
Beschreibung:
DOM3Z, also known as NG6 or DOM3L, is a 396 amino acid ubiquitously expressed protein belonging to the Dom3Z family. The gene encoding DOM3Z maps to human chromosome 6 in the major histocompatibility complex (MHC) class III region. Chromosome 6 contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease and Stickler syndrome are all associated with genes that map to chromosome 6.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10127R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10127R-A750
Lokale Artikelnummer::
BOSSBS-10127R-A750
Beschreibung:
Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated Signalling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated Signalling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated Signalling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other Signalling molecules.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
CD309, also known as VEGF-R2, KDR3, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGF-R2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGF-R2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGF-R2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.
Artikel-Nr:
(BOSSBS-10451R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10451R-A647
Lokale Artikelnummer::
BOSSBS-10451R-A647
Beschreibung:
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7555R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7555R-A555
Lokale Artikelnummer::
BOSSBS-7555R-A555
Beschreibung:
EphA3 is a member of the Ephrin (Eph) family. The Ephrins and Eph-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the Ephrin A (EphA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the Ephrin B (EphB) class, which are transmembrane proteins. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9054R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9054R-HRP
Lokale Artikelnummer::
BOSSBS-9054R-HRP
Beschreibung:
DOM3Z, also known as NG6 or DOM3L, is a 396 amino acid ubiquitously expressed protein belonging to the Dom3Z family. The gene encoding DOM3Z maps to human chromosome 6 in the major histocompatibility complex (MHC) class III region. Chromosome 6 contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease and Stickler syndrome are all associated with genes that map to chromosome 6.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7974R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7974R-CY7
Lokale Artikelnummer::
BOSSBS-7974R-CY7
Beschreibung:
The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ATX2 belongs to the autosomal dominant cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, ophthalmoplegia, bulbar and extrapyramidal signs, peripheral neuropathy and dementia. ATX2 is caused by expansion of a CAG repeat in the coding region of ATX2. Longer expansions result in earlier onset of the disease. There are four named isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3953R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3953R-CY5
Lokale Artikelnummer::
BOSSBS-3953R-CY5
Beschreibung:
Cytochrome c oxidase subunit I (COI or MTCO1) is one of three mitochondrial DNA (mtDNA) encoded subunits (MTCO1, MTCO2, MTCO3) of respiratory Complex IV. Complex IV is located within the mitochondrial inner membrane and is the third and final enzyme of the electron transport chain of mitochondrial oxidative phosphorylation. Complex IV is composed of 13 polypeptides. Subunits I, II, and III (MTCO1, MTCO2, MTCO3) are encoded by mtDNA while subunits IV, Va, Vb, VIa, VIb, VIc, VIIa, VIIb, VIIc, and VIII are nuclear encoded. Mammalian MTCO1 has 12 membrane-spanning alpha-helices (I to XII).
VE:
1 * 100 µl
Artikel-Nr:
(HONE31235.9025)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
31235.9025
Lokale Artikelnummer::
HONE31235.9025
Beschreibung:
Eisen(III)sulfat
VE:
1 * 25 kg
Lieferant:
MP Biomedicals
Beschreibung:
Sudan III is used in Coloring oils, sprit, lacquers etc; also as stain for zoological, pathological and vegetable objects like wax, cutin, resin, contents of lactiferous ducts etc, which are colored red, while cellulose membranes remain uncolored. Approved by FDA for external use only.
Lieferant:
MP Biomedicals
Beschreibung:
Soluble in water, alcohol, ether, acetone; practically insoluble in ethyl acetate.
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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