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1-Bromo-3-(2,2-difluoropropyl)benzene
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1-Bromo-3-(2,2-difluoropropyl)benzene
Artikel-Nr:
(BOSSBS-9047R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9047R-A488
Lokale Artikelnummer::
BOSSBS-9047R-A488
Beschreibung:
Voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarization and plays a central role in taste transduction. Monovalent-specific, non-selective cation channel that mediates the transport of Na(+), K(+) and Cs(+) ions equally well. Activated directly by increases in intracellular Ca(2+), but is impermeable to it. Gating is voltage-dependent and displays rapid activation and deactivation kinetics upon channel stimulation even during sustained elevations in Ca(2+). Also activated by a fast intracellular Ca(2+) increase in response to inositol 1,4,5-triphosphate-producing receptor agonists. The channel is blocked by extracellular acidification. External acidification has 2 effects, a fast reversible block of the current and a slower irreversible enhancement of current inactivation. Is a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. Heat activation is due to a shift of the voltage-dependent activation curve to negative potentials. Activated by arachidonic acid in vitro. May be involved in perception of bitter, sweet and umami tastes. May also be involved in sensing semiochemicals.
VE:
1 * 100 µl
Lieferant:
HIRSCHMANN
Beschreibung:
DURAN®, Borosilikatglas 3.3, mit PE-Stopfen, konformitätsbescheinigt (DE-M gekennzeichnet).
Lieferant:
Restek
Beschreibung:
Recommended for use with Rtx®-5 Amine, Rtx®-35 Amine, Rtx®-Volatile Amine, and Stabilwax®-DB capillary columns.
Lieferant:
SciLabware
Beschreibung:
PYREX®, Borosilikatglass, Quickfit®-Schliffe, klar.
Artikel-Nr:
(JALC00ABI24/35)
Lieferant:
Jallatte
Hersteller-Artikelnummer::
00ABI24/35
Lokale Artikelnummer::
JALC00ABI24/35
Beschreibung:
Anti-static shoes made from water resistant microfiber upper. Washable in soap and water.
VE:
1 * 1 PAAR
Artikel-Nr:
(BOSSBS-9067R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-CY5
Lokale Artikelnummer::
BOSSBS-9067R-CY5
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9067R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-FITC
Lokale Artikelnummer::
BOSSBS-9067R-FITC
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9067R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-A350
Lokale Artikelnummer::
BOSSBS-9067R-A350
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
2,6-Dichlorphenol-indophenol Natriumsalz Hydrat ACS, Sigma-Aldrich®
Artikel-Nr:
(SIAL251062-25G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
251062-25G
Lokale Artikelnummer::
SIAL251062-25G
Beschreibung:
4-Methoxy-2,6-bis(2-methyl-2-propanyl)phenol, Sigma-Aldrich®
VE:
1 * 25 g
Artikel-Nr:
(SIAL306010-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
306010-5G
Lokale Artikelnummer::
SIAL306010-5G
Beschreibung:
1,3-Difluor-5-nitrobenzol, Sigma-Aldrich®
VE:
1 * 5 g
Artikel-Nr:
(GESTPZ35EB)
Lieferant:
GESTIGKEIT HARRY
Hersteller-Artikelnummer::
PZ35EB
Lokale Artikelnummer::
GESTPZ35EB
Beschreibung:
This precision hotplate is equipped with adjustable temperature sensors (100 to 350 °C). These sensors function as an emergency control which protects the appliance and the substance being heated from dangerous overheating.
VE:
1 * 1 ST
Artikel-Nr:
(DALL3301271)
Lieferant:
HONEYWELL SAFETY
Hersteller-Artikelnummer::
3301271
Lokale Artikelnummer::
DALL3301271
Beschreibung:
The Leight Source 500 dispenser provides a highly visible permanent hearing protection source.
VE:
1 * 500 PAAR
Lieferant:
COMBI-BLOCKS
Beschreibung:
3,4-Difluor-2-methoxyanilin
Artikel-Nr:
(114-4336)
Lieferant:
Jallatte
Hersteller-Artikelnummer::
JJD09/35
Lokale Artikelnummer::
JALCJJD09/35
Beschreibung:
Schnürschuhe aus Vollleder mit Nylonfutter und extradichter Sohle.
VE:
1 * 1 PAAR
Lieferant:
Restek
Beschreibung:
Use these liners for increased sensitivity. They are manufactured from borosilicate glass or metal.
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
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